Shota Yamashita

Dynamic Tumor Volume Changes after Debulking Surgery of Optic Hypothalamus Pilocytic Astrocytoma

Masayuki Kanamori, Yoshiteru Shimoda, Yohei Morishita, Hidetaka Niizuma et autres

Debulking surgery is a treatment option for optic hypothalamic pilocytic astrocytoma. This study aimed to clarify the changes in magnetic resonance imaging following debulking surgery. We retrospectively reviewed the clinical and magnetic resonance imaging data of patients with optic hypothalamic pilocytic astrocytoma …

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Consolidation reduced-dose whole-brain radiation therapy with response-adapted boost in older patients with newly diagnosed primary central nervous system lymphoma

Shota Yamashita, Masayuki Kanamori, Masaki Kubozono, Yoshiteru Shimoda et autres

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Long-term intelligence after high-dose radiotherapy to the primary site versus chemotherapy and whole-ventricle radiotherapy in patients with germinoma

Masayuki Kanamori, Yumi Sugawara, Yoshiteru Shimoda, Osamu Iizuka et autres

BACKGROUND: Until 1995, patients with newly diagnosed germinoma received 40-60 Gy of radiation to the primary site with or without chemotherapy (regimen A). After 2000, treatment shifted to chemotherapy followed by 24 Gy of whole-ventricle radiation therapy (WVRT) (regimen B). This study …

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A Ruptured Distal Posterior Inferior Cerebellar Artery Aneurysm Treated with Open Surgery: A Case Report

Takeyoshi Honta, Kunihiko Umezawa, Shota Yamashita, Atsushi Nakayashiki et autres

非典型的な血腫分布を呈する後頭蓋窩出血性病変では，出血源検索および治療戦略に難渋することがある．今回われわれは，開頭術により確定診断，出血源処置，頭蓋内圧管理を一期的に施行し得たdistal posterior inferior cerebellar artery（PICA）動脈瘤破裂の1例を報告する．

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LncRNA CCDC152 coordinates a tumor-associated selenoprotein P cycle that sustains selenium-dependent redox homeostasis in glioblastoma

Stephanie Siu, Hiroki Taguchi, Xi Zheng, Hikari Sugiura et autres

Early Postoperative Venous Thromboembolism After Tumor Resection for Diffuse Gliomas: Diagnosis and Implications for Preventing Symptomatic Venous Thromboembolism

Yoshinari Osada, Masayuki Kanamori, Shota Yamashita, Yoshiteru Shimoda et autres

OBJECTIVE: Patients undergoing glioma resection are at high risk for venous thromboembolism (VTE), making early diagnosis and prevention critical. This retrospective single-institutional cohort analysis investigated the incidence of VTE on postoperative day (POD) 1 after diffuse glioma resection, screening effectiveness of plasma …

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Preoperative assessment of perforating arteries around amygdala glioblastoma using intra-arterial CT angiography with ultra-high-resolution CT and MR tractography: a case report

Gaku Inoue, Masayuki Kanamori, Shin-ichiro Osawa, Yoshiteru Shimoda et autres

Preservation of the perforating arteries (PAs) supplying the pyramidal tract (PT-PAs) is essential during glioblastoma resection. A 60-year-old man presented with sensory aphasia caused by a left medial temporal glioblastoma. To determine the surgical indication and strategy, we assessed the tumor's location …

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A Novel Method for Optimal Woven EndoBridge Device Sizing by Inscribing a Rectangle in Aneurysm Projections on 2-Dimensional Angiograms

Shota Yamashita, Yasuo Nishijima, Naoto Kimura, Hidenori Endo

The Woven EndoBridge device is used for endovascular treatment of wide-neck bifurcation cerebral aneurysms. Conventional sizing methods often result in oversizing and require subsequent resizing. Although recent studies demonstrated the accuracy of volumetric methods for sizing, they are often complex. We aimed …

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ALKBH1 drives codon-biased, pro-oncogenic translation and tumor microenvironment remodeling in glioma via tRNA wobble oxidation

Atsushi Nakayashiki, Arata Nagai, Yuko Iwasaki, Abdulrahman Mousa et autres

Abstract Gliomas rely on translational plasticity to sustain heterogeneity, stemness, and immune evasion. Here we identify the tRNA dioxygenase ALKBH1 as a central regulator of codon-biased translation and tumor microenvironment remodeling. LC-MS/MS profiling of patient tumors revealed enrichment of ALKBH1-mediated wobble cytidine …

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High-throughput FLIM flow cytometry with a continuous-wave laser

Hiroshi Kanno, Kotaro Hiramatsu, Hideharu Mikami, Atsushi Nakayashiki et autres

Publisher Correction: High-throughput fluorescence lifetime imaging flow cytometry

Hiroshi Kanno, Kotaro Hiramatsu, Hideharu Mikami, Atsushi Nakayashiki et autres

The original version of this Article contained an error in Fig. 1b, in which key dashed lines were missing in the phase delay plot, and an error in Fig. 1c, where the symbol π was incorrectly denoted. The correct version of Fig. …

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Residual Pattern of the Hyperintense Area on T2-Weighted Magnetic Resonance Imaging After Initial Treatment Predicts the Pattern and Location of Recurrence in Patients with Newly Diagnosed Glioblastoma

Yoshiteru Shimoda, Masayuki Kanamori, Shota Yamashita, Ichiyo Shibahara et autres

OBJECTIVE: This study examined the clinical significance of residual hyperintense area on T2-weighted magnetic resonance imaging (T2R) without gadolinium-enhanced lesions at the end of initial treatment (debulking surgery, concomitant radiotherapy, and temozolomide) in patients with glioblastoma. METHODS: Among 150 glioblastoma cases, 77 …

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