Accès ouvert
2026
article
OpenAlex
Karin M. Ekström, Nazia Riaz, Karolina Larsson, Afrodíté Németh et autres
BACKGROUND: Extracellular vesicles (EVs) are emerging as non-invasive biomarkers in cancer, but their role in monitoring the response to neoadjuvant systemic treatment (NST) in patients with breast cancer remains unclear. This study aimed to assess whether EV concentration and surface marker profiles …
se, hu
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Karin M. Ekström, Nazia Riaz, Karolina Larsson, Afrodíté Németh et autres
Supplementary Material 1
se, hu
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Karin Ekström, Nazia Riaz, Karolina Larsson, Afrodíté Németh et autres
Abstract Background Extracellular vesicles (EVs) are emerging as non-invasive biomarkers in cancer, but their role in monitoring the response to neoadjuvant systemic treatment (NST) in patients with breast cancer remains unclear. This study aimed to assess whether EV concentration and surface marker …
se, hu
(code pays fourni par la source)
Accès ouvert
2026
other
OpenAlex
Karin Ekström, Nazia Riaz, Karolina Larsson, Afrodíté Németh et autres
Abstract Background Extracellular vesicles (EVs) are emerging as non-invasive biomarkers in cancer, but their role in monitoring the response to neoadjuvant systemic treatment (NST) in patients with breast cancer remains unclear. This study aimed to assess whether EV concentration and surface marker …
se, hu
(code pays fourni par la source)
Accès ouvert
2026
article
OpenAlex
Karin M. Ekström, Nazia Riaz, Karolina Larsson, Afrodíté Németh et autres
Supplementary Material 1
se, hu
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Emilia Marta Marchelek, Afrodíté Németh, Sidhesh Mohak, Kamilla Varga et autres
Dendritic cells (DCs) are a heterogeneous population known for antigen presentation and immune modulation, playing a key role in priming a T cell response against pathogens and tumor cells. Despite their putative therapeutic value, their scarcity in peripheral blood limited their direct …
gb, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Afrodíté Németh, Gréta L. Bányai, Mátyás Andrészek, Nikolett Kitti Dobos et autres
Cell migration plays a central role in tumor progression and metastasis, making it a critical parameter in both cancer biology and therapeutic evaluation. A range of in vitro migration assays are commonly used to assess treatment-induced effects on motility, each with distinct …
hu
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Dorottya Kocsis, Dániel Sztankovics, Liza Józsa, Afrodíté Németh et autres
In recent times, with the need for a reduction, refinement, and replacement of in vivo animal testing, there has been an increasing demand for the use of relevant in vitro human cell systems in drug development. There is also a great demand …
hu
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Dorottya Kocsis, Dániel Sztankovics, Liza Józsa, Afrodíté Németh et autres
In recent times, with the decline of in vivo animal experiments, there has been an increasing demand for the use of relevant in vitro human cell systems in the development of new drugs. Furthermore, the production of artificial tissues and tissue engineering …
hu
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Afrodíté Németh, Gréta L. Bányai, Nikolett Kitti Dobos, Tamás Kós et autres
Extracellular vesicles (EVs) constitute a vital component of intercellular communication, exerting significant influence on metastasis formation and drug resistance mechanisms. Malignant melanoma (MM) is one of the deadliest forms of skin cancers, because of its high metastatic potential and often acquired resistance …
hu
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Afrodíté Németh, Gréta L. Bányai, Nikolett Kitti Dobos, Tamás Kós et autres
Abstract Extracellular vesicles (EVs) were found to be one group of the determining factors in intercellular communication and have been shown to have a crucial role in metastasis formation and drug resistance. Malignant melanoma (MM) is one of the deadliest forms of …
hu
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Éva Wisniewski, Domonkos Czárán, Fanni Kovács, Enikő Bahurek et autres
ARHGAP25, a RAC-specific GTPase activating protein (GAP), is an essential regulator of phagocyte effector functions such as phagocytosis, superoxide production, and transendothelial migration. Furthermore, its complex role in tumor behavior has recently been recognized. We previously demonstrated that phosphorylation of serine 363 …
hu
(code pays fourni par la source)