Yang‐Ching Chen

The Additive Value of Training Evaluations for Predicting Early-Career Doctor Retention: A Real-World Evidence (Preprint)

Yu-Hsiang Liu, Enoch Kang, Che‐Wei Lin, Yang‐Ching Chen

BACKGROUND The global shortage of physicians poses a significant threat to healthcare systems and health outcomes. While training and evaluations are identified as potential factors influencing physician retention, few studies have explored their predictive role. OBJECTIVE This study aims to investigate how …

Combined Associations of Lead and Arsenic Species with Liver Dysfunction and Hepatic Fibrosis Among Young Adults in Taiwan

Kai-Wei Liao, Chih‐Wen Wang, Wei-Lun Hung, Yuehua Chen et autres

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Transitions in stress, depression, and self-esteem across pubertal onset in children with central precocious puberty

Wei-Chen Chiang, Yu-Wen Huang, Chia-Min Kuo, Wei-Ying Chien et autres

PURPOSE: To compare psychological well-being of individuals with and without central precocious puberty (CPP) before and after pubertal onset METHODS: Perceived stress, depressive symptoms, and self-esteem were assessed in girls aged 6-14 years (n = 1699) and boys aged 9-17 years (n …

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Supplementary Materials for: Milk-Based Sugar-Sweetened Beverages, Timing, and Gene–Diet Interactions in Central Precocious Puberty

Sung‐En Lin, Yu-Hsiang Liu, Zheying Liu, Chien-Ming Lin et autres

This record contains supplementary tables and figures supporting the manuscript: "Milk-Based Sugar-Sweetened Beverages, Timing, and Gene–Diet Interactions in Central Precocious Puberty." The supplementary materials include detailed statistical analyses, hormone profiles, and genome-wide interaction study (GWIS) results. These data provide additional methodological details …

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Supplementary Materials for: Milk-Based Sugar-Sweetened Beverages, Timing, and Gene–Diet Interactions in Central Precocious Puberty

Sung‐En Lin, Yu-Hsiang Liu, Zheying Liu, Chien-Ming Lin et autres

This record contains supplementary tables and figures supporting the manuscript: "Milk-Based Sugar-Sweetened Beverages, Timing, and Gene–Diet Interactions in Central Precocious Puberty." The supplementary materials include detailed statistical analyses, hormone profiles, and genome-wide interaction study (GWIS) results. These data provide additional methodological details …

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Global prevalences of erythropoiesis-associated micronutrient deficiencies (iron, folate, and vitamin B 12 ) among pregnant women: a systematic review and meta-analysis

Nhi Thi Hong Nguyen, Yang‐Ching Chen, Nguyen Thanh Nhu, Bui Bao Hoang et autres

BACKGROUND: Deficiencies of iron, folate, and vitamin B12 micronutrients are considered a global public health issue. These deficiencies not only lead to anemia but are also linked to numerous short- and long-term health risks for both mothers and children. This study aimed …

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Comparative Efficacy of GnRHa Monotherapy vs Combination Therapy for Central Precocious Puberty

Hsien‐Yu Fan, Meng‐Che Tsai, Hsin-Yuan Chang, Chien‐Ming Lin et autres

CONTEXT: Central precocious puberty (CPP) can reduce adult height. Studies comparing the efficacy of gonadotropin-releasing hormone analogue (GnRHa) monotherapy with combination therapies show inconsistency. OBJECTIVE: This work aims to synthesize evidence comparing the effects of GnRHa monotherapy and combination therapies on height-related …

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Depression and anxiety in inflammatory bowel disease: mechanisms and emerging therapeutics targeting the microbiota-gut-brain axis

Yan Qian, Yang‐Ching Chen, Linquan Liu, Ting Wu et autres

Inflammatory bowel disease (IBD), encompassing ulcerative colitis (UC) and Crohn's disease (CD), represents a group of chronic, relapsing intestinal inflammatory disorders with incompletely understood etiology. Depression and anxiety, as prevalent psychiatric conditions, exhibit rising incidence rates; notably, IBD patients demonstrate heightened susceptibility …

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Response to Letter to the Editor for “Effect of Intraoperative Image-Guided Spinal Navigation Technologies on Endoscopic Lumbar Spine Surgery: A Systematic Review and Meta-Analysis”

Ying-Fong Su, Garcia de Oliveira Rafael, Abhinav K. Sharma, Yang‐Ching Chen et autres

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Maternal Fish Oil Intake and Early Childhood Allergic Rhinitis: cohort associations supported by a mouse model

Chung‐Hsiung Huang, Jia-Shan Liu, Yao‐Hsu Yang, Shih‐Yuan Hsu et autres

Maternal fish oil (FO) intake during pregnancy may reduce the risk of allergic rhinitis (AR) in offspring. This study integrated a human birth cohort ( n = 804) and a mouse model to explore this relationship and underlying mechanisms. Maternal FO intake …

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Choosing sweeteners wisely—nutrigenetic study on childhood obesity

D. Qiu, Shih‐Yuan Hsu, Emily Chia‐Yu Su, San‐Yuan Wang et autres

BACKGROUND: This study investigated the association of specific sweet-taste and obesity-related genes with sweetener consumption patterns among children and the interaction between these genetic factors and sweetener intake on the risk of childhood obesity. By leveraging data from the Taiwanese Pubertal Longitudinal …

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SUN-181 Sweeteners and Puberty: Investigating Genetic and Dietary Influences on Central Precocious Puberty

Yang‐Ching Chen

Abstract Disclosure: Y. Chen: None. Introduction: Central Precocious Puberty (CPP), marked by early secondary sexual characteristics due to premature hypothalamic-pituitary-gonadal axis activation, is increasingly prevalent. Understanding genetic and dietary factors, particularly sweeteners, is crucial for mitigating CPP's health impacts. Our prior research, …

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