Kenji Ishii

Retraction notice to “Generation of a gene-corrected human isogenic iPSC line from an Alzheimer’s disease iPSC line carrying the PSEN1 H163R mutation” [Stem Cell Res. 79 (2024) 103495]

Damián Hernández, Stephanie Morgan Schlicht, Jordan Clarke, Maciej Daniszewski et autres

au, us (code pays fourni par la source)

Quantitative validation of data-driven motion correction for brain PET using phantom with motion generator system

Yuto Kamitaka, Muneyuki Sakata, Keiichi Oda, Akie Katsuki et autres

BACKGROUND: Head motion during brain positron emission tomography (PET) degrades image quality and quantitative accuracy. Therefore, a data-driven motion correction (MC) method utilizing ultrafast list-mode reconstruction technology has been proposed and shown to considerably improve image quality. However, reproducing accurate actual motions …

jp, es (code pays fourni par la source)

Measuring piping erosion rate in bentonite using spectrophotometry and X-ray computed tomography

Norihisa Osawa, Tomoko Ishii, Kenji Ishii, Yuichi Niibori

jp (code pays fourni par la source)

18F-MK-6240 uptake in cortical tau and hemorrhagic lesions in a case of Alzheimer’s disease with possible crossed aphasia

Masaki Ikeda, Kenji Ishibashi, Masakuni Amari, Masaru Matsumura et autres

We report neuroimaging findings from a 74-year-old right-handed male with Alzheimer’s disease (AD) and lesions of cerebral amyloid angiopathy (CAA), utilizing 11 C-PiB-PET, 18 F-THK5351-PET, and 18 F-MK-6240-PET. 11 C-PiB-PET showed positive findings consistent with AD. 18 F-THK5351 accumulated in regions of …

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Potential of Hybrid PSF Correction to Suppress Gibbs Artifacts in PET Imaging

Tsubasa Hirakawa, Kei Wagatsuma, Muneyuki Sakata, Yuto Kamitaka et autres

Point-spread-function (PSF) correction is used to compensate for the degradation of spatial resolution in positron emission tomography (PET) imaging. PSF correction improves image contrast and reduces image noise. However, it also causes Gibbs artifacts, which appear as signal overshoot along object edges, …

jp, es (code pays fourni par la source)

Lower Firmicutes abundance in gut microbiota associated with amyloid-β positivity in older adults in Japan as assessed by positron emission tomography

Narumi Kojima, Yosuke Osuka, Hiroyuki Sasai, Shoji Shinkai et autres

BACKGROUND: Alzheimer's disease, marked by amyloid-β accumulation, is a leading cause of dementia. Gut microbiota may influence its development by affecting inflammation or amyloid-β metabolism. However, this association is not well studied in older adults in Japan, whose characteristic diet may uniquely …

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Immediate reactions to amyloid PET disclosure in Japanese older adults without dementia

Kenichiro Sato, Yoshiki Niimi, Ryoko Ihara, Takeshi Ikeuchi et autres

INTRODUCTION: Amyloid positron emission tomography (PET) has become increasingly important for detection of early Alzheimer's disease (AD) and eligibility for emerging disease-modifying therapies. While North American and European studies report limited short-term psychological harm following disclosure of amyloid status in asymptomatic individuals, …

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[Donanemab, an Amyloid β-targeting Antibody for Early Symptomatic Alzheimer's Disease: Summary of Clinical Study Results].

Shoichiro Sato, Atsushi Iwata, Kenji Ishii, Eriko Kamiki et autres

Alzheimer's disease is an age-related neurodegenerative disorder, and is considered to contribute to dementia in 60%-70% of individuals with dementia. In recent years, a series of amyloid β protein (Aβ)-targeting antibodies that act directly on Aβ aggregates in the brain, one of …

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18 F-FDG PET for the differential diagnosis of Alzheimer's disease and frontotemporal lobar degeneration: A multicenter prospective study in Japan

Kengo Ito, Yukihiko Washimi, Takashi Kato, Keisuke Suzuki et autres

Background 18 F-fluoro-2-deoxy-2-D-glucose positron emission tomography ( 18 F-FDG PET) is a biomarker of neuronal injury, according to the revised National Institute on Aging-Alzheimer's Association criteria. Objective This multicenter prospective cohort study aimed to evaluate the value of 18 F-FDG PET for …

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Effect of Silica Fillers on the Curing Reaction of Epoxy-imidazole Thermoset Resin

Kensuke Naka, Yoshitomo Furushima, Takashi Hirano, Yoshihiko Taguchi et autres

Epoxy-imidazole thermosetting resins undergo a complex reaction mechanism when heated, involving two simultaneous processes: exothermic addition polymerization and endothermic reactions, during which the catalyst, imidazole, is regenerated. Consequently, the relationship between conversion and glass transition temperature ($T_{\mathrm{g}}$) varies depending on the curing …

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Diagnostic Challenge in Frontal Variant Alzheimer's Disease With Low Amyloid‐β PET Retention

Ryosuke Shimasaki, Masanori Kurihara, Kenji Ishibashi, Aya M. Tokumaru et autres

Diagnosing frontal variant Alzheimer's disease (fvAD) is difficult and could be even more difficult when amyloid-beta (Aβ) PET retention is low. A 63-year-old woman presenting with a 3-year history of apathy and memory impairment showed executive dysfunction, memory impairment, and severe bilateral …

jp (code pays fourni par la source)

P367 – Impact of fluorescence cystoscopy using oral 5-aminolevulinic acid on risk evaluation and patient prognosis in transurethral resection for primary non-muscle invasive bladder cancer

Y. Ishikawa, Haruka Tanaka, Satoshi Matsuoka, Kenji Ishii et autres