Raida Ben Rayana

CD40.HIVEnv, an antibody mediated vaccine, induces long-term and recall immunogenicity in non-HIV-1 infected volunteers

Yves Levy, Christiane Moog, Aurélie Wiedemann, Odile Launay et autres

The ANRS VRI06 trial investigated CD40.HIVRI.Env, an Antibody Mediated Vaccine composed by a CD40 monoclonal antibody fused with gp140 Env, designed to target antigen to dendritic cells. Initial results in 72 HIV-uninfected volunteers showed that administration of 0.3-3.0 mg of CD40.HIVRI.Env, given …

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Remodeling of immune system functions by extracellular vesicles

Déborah Neyrinck-Leglantier, Marie Tamagne, Raida Ben Rayana, Souganya Many et autres

Introduction: The treatment of chronic viral infections can often bring viral replication under control. However, chronic immune activation persists and can lead to the development of comorbid conditions, such as cardiovascular disease and cancer. This is particularly true for people living with …

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Immunoregulatory molecule expression on extracellular microvesicles in people living with HIV

Déborah Neyrinck-Leglantier, Marie Tamagne, Raida Ben Rayana, Souganya Many et autres

Introduction: People living with HIV (PLWH) now benefit from combined antiviral treatments that durably control viral replication. These antiretroviral treatments decrease mortality and improve quality of life in PLWH, but do not completely control the excessive non-specific activation of the immune system …

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“They Have to Make an Effort Too”: What Decliners Can Teach Us About HIV Cure/Remission-Related Clinical Trials? Results from a French Qualitative Study

Sarah Lefebvre, Jean‐Daniel Lelièvre, Véronique Rieux, Laurence M. Weiss et autres

Only one study to date has focused on people living with HIV (PLWH) who refused to participate in a HIV cure/remission-related clinical trial (HCCT)-"decliners" hereafter-that included analytical treatment interruption (ATI). Exploring why these persons refuse may provide valuable information to ensure more …

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Depressive symptoms after hepatitis C cure and socio-behavioral correlates in aging people living with HIV (ANRS CO13 HEPAVIH)

Fabienne Marcellin, Sylvie Brégigeon, Clémence Ramier, Camélia Protopopescu et autres

Background & Aims: A growing literature shows an improvement of chronic hepatitis C virus (HCV)-related depression after successful treatment with direct-acting antivirals. However, depression after HCV cure remains insufficiently documented in people living with HIV (PLWH) and HCV, a population with specific …

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HCV cure: an appropriate moment to reduce cannabis use in people living with HIV? (ANRS CO13 HEPAVIH data)

Tangui Barré, P. Mercié, Caroline Lions, Patrick Miailhes et autres

BACKGROUND: Thanks to direct-acting antivirals, hepatitis C virus (HCV) infection can be cured, with similar rates in HCV-infected and HIV-HCV co-infected patients. HCV cure is likely to foster behavioral changes in psychoactive substance use, which is highly prevalent in people living with …

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Cannabis Use and Plasma Human Immunodeficiency Virus (HIV) RNA Levels in Patients Coinfected With HIV and Hepatitis C Virus Receiving Antiretroviral Therapy: Data From the ANRS CO13 HEPAVIH Cohort

Fabienne Marcellin, Patrick Miailhes, Melina E. Santos, P. Mercié et autres

To the Editor—Chaillon et al [1] reported interesting results on the effect of cannabis use on the human immunodeficiency virus (HIV) reservoir during suppressive antiretroviral therapy (ART) among 48 men who have sex with men (MSM) with primary or recent HIV infection, …

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Patient-reported symptoms during direct-acting antiviral treatment: A real-life study in HIV-HCV coinfected patients (ANRS CO13 HEPAVIH)

Fabienne Marcellin, Vincent Di Beo, Hugues Aumaître, Marion Mora et autres

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