Sara Martínez‐Castro

Persistent tissue hypoperfusion improves risk stratification beyond vasopressor dose in refractory septic shock: a secondary analysis of the ANDROMEDA-SHOCK-2 trial

Eduardo Kattan, Gustavo A. Ospina-Tascón, Nicolas Orozco, J C Teboul et autres

cl, ru, fr, co, ch, at, de, mx, us, it, in, es, pl, br, be, nl (code pays fourni par la source)

Personalized Hemodynamic Resuscitation Targeting Capillary Refill Time in Early Septic Shock

Fernando Pálizas, Bernardo Lattanzio, Natalia Durandal, María Eugenia Alonso et autres

Importance: The optimal strategy for hemodynamic resuscitation in early septic shock remains uncertain. Objective: To determine the effect of a personalized hemodynamic resuscitation protocol targeting capillary refill time (CRT-PHR) on a hierarchical composite outcome of mortality, duration of vital support, and length …

es, ar, cl (code pays fourni par la source)

Publisher Correction: Early corticosteroids are associated with lower mortality in critically ill patients with COVID‑19: a cohort study

Pablo Monedero, Ángel M. Candela-Toha, María L. Hernández-Sanz, Egoitz Arruti et autres

es, ca (code pays fourni par la source)

Are all ventilators for NIV performing the same? A bench analysis

Sara Martínez‐Castro, Francisco Javier Belda Nacher, Jaume Puig Bernabeu, Marina B Soro Domingo et autres

Global pandemic due to COVID-19 has increased the interest for ventilators´ use worldwide. New devices have been developed and older ones have undergone a renewed interest, but we lack robust evidence about performance of each ventilator to match appropriate device to a …

es (code pays fourni par la source)

Sedation with Sevoflurane versus Propofol in COVID-19 Patients with Acute Respiratory Distress Syndrome: Results from a Randomized Clinical Trial

Sara Martínez‐Castro, Berta Monleón, Jaume Puig, C. Ferrer Gómez et autres

BACKGROUND: Acute respiratory distress syndrome (ARDS) related to COVID-19 (coronavirus disease 2019) led to intensive care units (ICUs) collapse. Amalgams of sedative agents (including volatile anesthetics) were used due to the clinical shortage of intravenous drugs (mainly propofol and midazolam). METHODS: A …

es (code pays fourni par la source)

Evaluation of functional warm ischemia time during controlled donation after circulatory determination of death using normothermic regional perfusion ( ECMO‐TT ): A prospective multicenter cohort study

Sara Martínez‐Castro, Rosalía Navarro, María Luisa García‐Pérez, José Manuel Segura et autres

BACKGROUND: Controlled donation after circulatory determination of death (cDCD) seems an effective way to mitigate the critical shortage of available organs for transplant worldwide. As a recently developed procedure for organ retrieval, some questions remain unsolved such as the uncertainty regarding the …

es (code pays fourni par la source)

Early corticosteroids are associated with lower mortality in critically ill patients with COVID-19: a cohort study

Alfredo Gea, Ángel M. Candela-Toha, María L. Hernández-Sanz, Egoitz Arruti et autres

BACKGROUND: Critically ill patients with coronavirus disease 19 (COVID-19) have a high fatality rate likely due to a dysregulated immune response. Corticosteroids could attenuate this inappropriate response, although there are still some concerns regarding its use, timing, and dose. METHODS: This is …

es, ca (code pays fourni par la source)

Awake prone positioning does not reduce the risk of intubation in COVID-19 treated with high-flow nasal oxygen therapy: a multicenter, adjusted cohort study

Carlos Ferrando, Ricard Mellado Artigas, Alfredo Gea, Egoitz Arruti et autres

BACKGROUND: Awake prone positioning (awake-PP) in non-intubated coronavirus disease 2019 (COVID-19) patients could avoid endotracheal intubation, reduce the use of critical care resources, and improve survival. We aimed to examine whether the combination of high-flow nasal oxygen therapy (HFNO) with awake-PP prevents …

es, us (code pays fourni par la source)

Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS

Carlos Ferrando, Fernando Suárez-Sipmann, Ricard Mellado Artigas, María Hernández et autres

es, se, us, ca (code pays fourni par la source)

Optimizing ceftolozane-tazobactam dosage during continuous renal replacement therapy: some nuances

Gerardo Aguilar, Rafael Ferriols, Sara Martínez‐Castro, Carlos Ezquer et autres

es (code pays fourni par la source)

Optimizing ceftolozane-tazobactam dosage in critically ill patients during continuous venovenous hemodiafiltration

Gerardo Aguilar, Rafael Ferriols, Sara Martínez‐Castro, Carlos Ezquer et autres

Ceftolozane-tazobactam (C/T), the combination of a new cephalosporin with a classic β-lactamase inhibitor, is currently considered the most active betalactam antibiotic against P. aeruginosa [1].Despite several case reports on C/T pharmacokinetics in critically ill patients during continuous renal replacement therapy (CRRT) [2-4], …

es (code pays fourni par la source)