Ying Lu

Identification and Validation of Reference Genes for Quantitative Real-Time PCR in Corydalis saxicola Under Various Abiotic Stresses

Liang Kang, Zhaodi Wen, Han Liu, Ying Lu et autres

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Mitotic Exit Control in Budding Yeast: Regulators and Dynamics

Ying Lu

In budding yeast, the phosphatase Cdc14 is released from nucleolus to promote mitotic exit (ME). Cdc14 release and ME is controlled by mitotic cyclin-Cdk oscillation, the FEAR network including a non-proteolytic function of separase (Esp1), and the Mitotic Exit Network (MEN) indirectly …

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Episodic transport of protein aggregates achieves a positive size selectivity in aggresome formation

Rui Fang, Luolan Bai, Bert M. Verheijen, Boyan Li et autres

Eukaryotic cells direct toxic misfolded proteins to various quality control pathways based on their chemical properties and aggregation status. Aggregated proteins are targeted to selective autophagy or specifically sequestered into the "aggresome", a perinuclear inclusion at the microtubule-organizing center (MTOC). However, the …

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A fake news detection model using the integration of multimodal attention mechanism and residual convolutional network

Ying Lu

To improve the accuracy and efficiency of fake news detection, this study proposes a deep learning model that integrates residual networks with attention mechanisms. Building on traditional convolutional neural networks, the model incorporates multi-head attention mechanisms to enhance the extraction of key …

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Genome-Wide Characterization of the ANN Gene Family in Corydalis saxicola Bunting and the Role of CsANN1 in Dehydrocavidine Biosynthesis

Han Liu, Jing Wang, Mei Qin, Ying Lu et autres

Annexins (ANNs) are a family of calcium (Ca2+)-dependent and phospholipid-binding proteins, which are implicated in the regulation of plant growth and development as well as protection from biotic and abiotic stresses. Corydalis saxicola Bunting, an endangered benzylisoquinoline alkaloid (BIA)-rich herbaceous plant, widely …

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Genome-Wide Characterization of the ANN Gene Family in Corydalis saxicola and the Role of CsANN1 in Dehydrocavidine Biosynthesis

Mei Qin, Ying Lu, Lirong Huang, Xia-lian Ou et autres

Annexins (ANNs), which are calcium (Ca2+)-dependent and phospholipid-binding protein families, are implicated in the regulation of plant growth and development as well as protection from various stresses. However, little is known about ANNs in Corydalis Saxicola, an endangered benzylisoquinoline alkaloid (BIA)-riched herbaceous …

Geodesic distance on Sierpinski-like carpet

Ying Lu, Qingcheng Zeng, Jiajun Xu, Lifeng Xi

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The grain size and domain structure synergistic effect on BNT based lead-free ceramics with high energy storage properties

Ying Lu, Xiaochun Wang, Peng Li, Juan Du et autres

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The Grain Size and Domain Structure Synergistic Effect on Bnt Based Lead-Free Ceramics with High Energy Storage Properties

Ying Lu, Xiaochun Wang, Peng Li, Juan Du et autres

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Simulating the conformational dynamics of the ATPase complex on proteasome using its free-energy landscape

Rui Fang, Ying Lu

The AAA+ ATPase complex on proteasome powers its functions through a series of intricate conformational transitions. Here, we describe a procedure to simulate the conformational dynamics of the proteasomal ATPase complex. We first empirically determined the free-energy landscape (FEL) of proteasome and …

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Trends in Single-Molecule Total Internal Reflection Fluorescence Imaging and Their Biological Applications with Lab-on-a-Chip Technology

Louis Colson, Youngeun Kwon, Soobin Nam, Avinashi Bhandari et autres

Single-molecule imaging technologies, especially those based on fluorescence, have been developed to probe both the equilibrium and dynamic properties of biomolecules at the single-molecular and quantitative levels. In this review, we provide an overview of the state-of-the-art advancements in single-molecule fluorescence imaging …

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Molecular mechanism for activation of the 26S proteasome by ZFAND5

Dong Hoon Lee, Yanan Zhu, Louis Colson, Xiaorong Wang et autres

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