Marko Vuković

Nectin-4 Expression in Muscle-Invasive Bladder Cancer Is Associated with Growth-Related and Inflammatory Signaling Pathways

Sebastian Jersinovic, Marko Vuković, Jörg Hennenlotter, Thomas Lütfrenk et autres

Nectin-4 has emerged as a clinically relevant target in muscle-invasive bladder cancer (MIBC), primarily because of its role in antibody–drug conjugate-based therapies. However, the broader biological context of Nectin-4 expression and its association with tumor-promoting signaling pathways in MIBC remain insufficiently characterized. …

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Prostate Cancer Mortality Trend in Montenegro 1990-2018

Mirjana Nedović Vuković, Milos Bojic, Marina Jakšić, Mileta Golubović et autres

Background: Prostate cancer is the fifth leading cause of cancer-related death among men worldwide, with an estimated 375,304 deaths in 2020 and a mortality rate of 7.7 deaths per 100,000. It stands as the leading cause of cancer mortality in 48 countries. …

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Medlar (Mespilus germanica L.) fruit morphology depending on fruit size

Damir Drvodelić, Ela Španjol, Marko Vuković, Tomislav Jemrić

The present study aims to investigate the effects of fruit size of medlar (Mespilus germanica L.) on fruit and seed morphology. Medlar fruits were harvested from the crowns of ten trees near Đulovac, Croatia, in autumn 2022 and 2023 at commercial maturity. …

Bladder Cancer Mortality Trend in Montenegro: 1990-2021

Zoran Terzić, Mileta Golubović, Marko Vuković

Background: Bladder cancer accounts for more than 200,000 deaths annually on a global level, with an age-standardized mortality rate of 2.9 per 100,000 individuals. Despite declining global rates, it remains a substantial public health burden. We aimed to analyze the mortality trend …

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Unfavorable low-risk factors predict pathologic upstaging and upgrading following radical prostatectomy: Evidence for further subclassification of low-risk prostate cancer?

Aleksandar Magdelinic, Aleksandar Spasic, Marko Vuković

Introduction/Objective. We aimed to validate the stratification of low-risk prostate cancer (PCa) into ?favorable? and ?unfavorable? subgroups of patients undergoing radical prostatectomy (RP), based on the correlation of various biopsy features with high-risk characteristics at final pathology. Methods. The research involved 173 …

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Total penectomy as treatment option for solitary penile metastasis in hormone sensitive metastatic prostate cancer (mHSPC): Case report with surgical technique

Marko Vuković, Marko Albijanic, Niko Radović

We present a case of a 66-year-old man with a three-year history of Gleason 10 prostate cancer (PCa), who presented with penile pain, erythema, and induration of the penile shaft. His cancer was treated with androgen deprivation therapy (ADT), radiotherapy, and apalutamide, …

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Wild pear (Pyrus pyraster (L.) Burgsd.) fruit and seed morphology depending on fruit size

Damir Drvodelić, Milan Oršanić, Marko Vuković, Tomislav Jemrić

The current study aims to evaluate the effects of fruit size of wild pear (Pyrus pyraster (L.) Burgsd.) on morphological fruit and seed traits. Wild pear fruit was collected from 10 trees in the area of Žumberačko gorje in the fall of …

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Interleukin-1β/Interleukin (IL)-1-Receptor-Antagonist (IL1-RA) Axis in Invasive Bladder Cancer—An Exploratory Analysis of Clinical and Tumor Biological Significance

Marko Vuković, Jorge M. Chamlati, Jörg Hennenlotter, Tilman Todenhöfer et autres

Previous data indicate a role of IL-1 and IL-1RA imbalance in bladder carcinoma (BC); the inhibition of IL-1 signaling might be considered a treatment option. Objective: To assess expression patterns and the prognostic role of IL-1β and IL-1RA in invasive BC and …

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Sociodemographic Characteristics and the Influence of Religion on the Knowledge of Doctors, Nurses, and the General Population in Montenegro About Transplant and Organ Donation.

Damir Peličić, Tanja Vojinović, Marko Vuković, Dalibor Bokan et autres

OBJECTIVES: The goal of our research was to determine the level of knowledge of healthcare workers and the general population about transplantation and organ donation through sociodemographic and religious aspects. MATERIALS AND METHODS: We conducted a cross-sectional study to provide insight on …

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How to treat jatrogenic ureteral injury after posterior spinal surgery? Case report and review of literature

Petar Kavarić, Aleksandar Magdelinic, Almir Rebronja, Marko Albijanic et autres

Introduction: Entry into the retroperitoneal space during open posterior spinal surgery introduces the rare possibility of iatrogenic ureteral injury. Case presentation: We describe a case of ureteral injury after spinal surgery in a 49-year-old female with persistent lumbar pain and high fever …

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Mapping European Association of Urology Guideline Practice Across Europe: An Audit of Androgen Deprivation Therapy Use Before Prostate Cancer Surgery in 6598 Cases in 187 Hospitals Across 31 European Countries

Steven J. MacLennan, Nuno Pereira‐Azevedo, Eilidh Duncan, Jennifer Dunsmore et autres

BACKGROUND: Evidence-practice gaps exist in urology. We previously surveyed European Association of Urology (EAU) guidelines for strong recommendations underpinned by high-certainty evidence that impact patient experience for which practice variations were suspected. The recommendation "Do not offer neoadjuvant androgen deprivation therapy (ADT) …

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Mini-laparotomy radical cystectomy with limited bowel externalization during ileal conduit urinary diversion reduces the rate of postoperative complications: a match-paired, single centered analysis

Dejan Djordjević, Svetomir Dragićević, Marko Vuković

Objective To assess the feasibility and functional outcomes of mini-laparotomy radical cystectomy (RC) in association with limited bowel externalization during ileal conduit urinary diversion.Methods Between January 2018 and March 2020, 53 patients underwent RC plus pelvic lymph node dissection (PLND) for invasive …

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