James R. Middleton

Triboelectric Charging Properties of the Functional Groups of Common Pharmaceutical Materials Using Density Functional Theory Calculations

James R. Middleton, Mojtaba Ghadiri, Andrew J. Scott

Triboelectrification is a ubiquitous and poorly understood phenomenon in powder processing, particularly for pharmaceutical powders. Charged particles can adhere to vessel walls, causing sheeting; they can also cause agglomeration, threatening the stability of powder formulations, and in extreme cases electrostatic discharges, which …

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Prediction of the Effective Work Function of Aspirin and Paracetamol Crystals by Density Functional Theory─A First-Principles Study

James R. Middleton, Andrew J. Scott, Richard A. Storey, Mariagrazia Marucci et autres

Crystals of active pharmaceutical ingredients (API) are prone to triboelectric charging due to their dielectric nature. This characteristic, coupled with their typically low density and often large aspect ratio, poses significant challenges in the manufacturing process. The pharmaceutical industry frequently encounters issues …

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Experimental parameter investigation for development of a control system for assessment of cardiovascular response to stress in student airline pilots

A. Avolio, Lingzhong Kong, James R. Middleton, A. Quasem et autres

Fault detection and diagnosis in gas control systems

James R. Middleton

Gas is transported via a large network of pipes which are operated over a wide range of pressures Within these networks are many elements which ensure that all the necessary working conditions are met. An important role is played by valves which …

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Unmanned Evaluation of the U.S. Navy MK 16 First Article Closed-Circuit UBA (Underwater Breathing Apparatus)

James R. Middleton

Abstract : The Navy Experimental Diving Unit (NEDU) conducted unmanned performance testing on two first production article MK 16 underwater breathing apparatus (UBA) in October 1982. Breathing resistance/breathing work and oxygen (O2) set-point control studies were conducted in the NEDU Experimental Diving …

Unmanned Evaluation of the U.S. Navy MK 15 Closed-Circuit UBA (underwater Breathing Apparatus).

James R. Middleton

The purpose of the unmanned testing on the U.S. Navy MK-15 closed- circuit (C/C) underwater breathing apparatus (UBA) using a hyperbaric breathing simulator was twofold: (1) to evaluate breathing resistance/breathing work characteristics of the MK-15 UBA using a variety of mouthpiece/hose and …

Evaluation of DIVEX AGA Commercial Mask

James R. Middleton, W. A. B. EVANS, M. G. Jantzen, R. C. Maulbeck

Abstract : An open circuit demand full-face mask (FFM) was evaluated in both manned and unmanned modes on air in accordance with NAVSEA Task No. 81-3. The mask, designed for use with open circuit (O/C) SCUBA, is produced by AGA SPIRO of …

Unmanned Evaluation of Six Closed-Circuit Oxygen Rebreathers.

James R. Middleton

Six closed-circuit (C/C) pure oxygen rebreathers were evaluated in the unmanned mode by the Navy Experimental Diving Unit in accordance with Naval Sea Systems Command Task Number 81-16. The purpose of the task was to provide performance data on existing rebreathers to …

Evaluation of Commercially Available, Wrist-Worn Depth Gauges.

James R. Middleton, Jonathan F. Tobias, Billy E. Webb

Abstract : Twenty-eight models of commercially available, diver, wrist-worn depth gauges were evaluated by the Navy Department Diving Unit. All gauges were tested to determine accuracy, repeatability, watertight integrity, thermal stability, durability, readability and luminescence capability. The depth gauges tested represented a …

Evaluation of the EFCOM SC-100M/120M/125M Wireless Underwater Communicator.

James R. Middleton

Abstract : In June 1981, the EFCOM SC-100M/120M/125M wireless communications system was evaluated in conjunction with the AGA DIVATOR 324 Full-Face Mask by the Navy Experimental Diving Unit. The purpose was to determine the systems suitability for U.S. Navy use with open-circuit …

Standardized NEDU Unmanned UBA Test Procedures and Performance Goals

James R. Middleton, Edward D. Thalmann

This report represents the most recent developments in a continuing effort by NEDU to accurately simulate the physiology of a working diver during unmanned UBA performance testing. The unmanned test procedures outlined in this document simulate the physiology of a diver performing …

Unmanned Evaluation of U.S. Navy MK 11 Semi-Closed Circuit Mixed Gas UBA

James R. Middleton

NEDU performed unmanned tests on the MK 11 UBA incorporating Field Change Number 979A (modified canister configuration containing a heated central core and Koegel check valves in the M-11 mask). Breathing resistance and canister duration were evaluated at depths ranging from 250 …