Sandra V. Kik

PET–CT benchmarked detection and 5-year progression of asymptomatic tuberculosis: a longitudinal, prospective cohort study

Hanif Esmail, Friedrich Thienemann, Bianca Sossen, Sandra Mukasa et autres

BACKGROUND: F]-fluorodeoxyglucose PET-CT) and compared with chest x-ray computer-aided detection (CAD). METHODS: We enrolled a prospective longitudinal cohort in Khayelitsha, Cape Town, South Africa, of asymptomatic, HIV-uninfected contacts aged 18-65 years of patients with rifampicin-resistant tuberculosis, a tuberculosis high-risk group not eligible …

Afrique du Sud, gb, au, us, de, ch, dk (code pays fourni par la source)

A multi-country head-to-head accuracy comparison of automated chest X-ray algorithms for tuberculosis

William Worodria, Rafaela Serra de Castro, Sandra V. Kik, Victoria Dalay et autres

RATIONALE: Computer-aided detection algorithms for automated chest X-ray reading have been endorsed by the World Health Organization for tuberculosis triage, but independent, multi-country assessment of current products is needed to guide implementation. OBJECTIVES: We included chest X-rays from adults who presented to …

Ouganda, us, ch, ph, Afrique du Sud, Tanzanie, vn, Madagascar, in, de, ca (code pays fourni par la source)

Validation of several TB-CAD chest-X-ray applications in individuals with presumptive TB visiting peripheral health institutes in Delhi State

Sandra V. Kik, Shruti Goel, Vindhya Vatsyayan, Sam Linsen et autres

ch, us, in (code pays fourni par la source)

Computer-aided reading of chest radiographs for paediatric tuberculosis: current status and future directions

M. G. Dupont, Robert Castro, Sandra V. Kik, Megan Palmer et autres

Computer-aided detection (CAD) systems for automated reading of chest x-rays (CXRs) have been developed and approved for tuberculosis triage in adults but not in children. However, CXR is frequently the only adjunctive tool for clinical assessment in the evaluation of paediatric tuberculosis …

us, ch, Afrique du Sud (code pays fourni par la source)

Novel and optimized diagnostics for pediatric TB in endemic countries: NOD-pedFEND study protocol

Rinn Song, Else M. Bijker, Grace P. Kisitu, Emily Douglass et autres

BACKGROUND: Pediatric tuberculosis is a major global public health challenge, with reliable diagnosis being a main obstacle to identifying and treating affected children. New and improved diagnostics, ideally on non-sputum samples, are urgently required, especially in the most vulnerable group of children …

gb, nl, Ouganda, us, ch, ca, pe (code pays fourni par la source)

Policies, practices, opportunities and challenges for tuberculosis screening: a global survey of national tuberculosis programmes

Liana Macpherson, Cecily Miller, Yohhei Hamada, Lele Rangaka et autres

INTRODUCTION: There are limited published data on how countries carry out screening for tuberculosis (TB) disease and what the perceived challenges are for implementing screening from a country perspective. Understanding these factors are important to enable better planning and support for the …

gb, ch, ca, dk (code pays fourni par la source)

Detection of other pathologies when utilising computer-assisted digital solutions for TB screening

J. Sebastián, Ioana D. Olaru, Athanasios Giannakis, Matthew Arentz et autres

BACKGROUND: Computer-aided detection (CAD) tools for TB detection have the potential to enable screening programmes and reduce the diagnostic gap in settings where access to radiologists is limited. However, there are concerns that other common chest X-ray (CXR) abnormalities not due to …

de, gb, gr, ch, Namibie (code pays fourni par la source)

Diagnostic Accuracy of Chest X-ray Computer-Aided Detection Software for Detection of Prevalent and Incident Tuberculosis in Household Contacts

Liana Macpherson, Sandra V. Kik, Matteo Quartagno, Francisco Lakay et autres

BACKGROUND: World Health Organization (WHO) tuberculosis (TB) screening guidelines recommend computer-aided detection (CAD) software for chest radiograph (CXR) interpretation. However, studies evaluating their diagnostic and prognostic accuracy are limited. METHODS: We conducted a prospective cohort study of household contacts of rifampicin-resistant TB …

gb, ch, Afrique du Sud, us, au (code pays fourni par la source)

Diagnostic Accuracy of Tuberculosis Screening Tests in a Prospective Multinational Cohort: Chest Radiography With Computer-Aided Detection, Xpert Tuberculosis Host Response, and C-Reactive Protein

Rebecca Crowder, Balamugesh Thangakunam, Alfred Andama, Devasahayam Jesudas Christopher et autres

BACKGROUND: Accessible, accurate screening tests are necessary to advance tuberculosis case finding and early detection in high-burden countries. METHODS: We prospectively screened adults with ≥2 weeks of cough at primary health centers in the Philippines, Vietnam, South Africa, Uganda, and India. Participants …

us, in, Ouganda, ph, Afrique du Sud, ch, th, vn, de, gb (code pays fourni par la source)

Computer-Aided Reading of Chest Radiographs for Pediatric Tuberculosis: Current Status and Future Directions

M. G. Dupont, Robert Castro, Sandra V. Kik, Megan Palmer et autres

SUMMARY Computer-aided detection (CAD) systems for automated reading of chest X-rays (CXRs) have been developed and approved for tuberculosis (TB) triage in adults, but not in children. However, CXR is frequently the only adjunctive tool to clinical assessment for the evaluation of …

us, ch, Afrique du Sud, gb (code pays fourni par la source)

Policies, practices, opportunities, and challenges for TB screening – A survey of sixty National TB Programmes

Liana Macpherson, Cecily Miller, Yohhei Hamada, Molebogeng X. Rangaka et autres

Abstract Background To meet incidence reduction goals, the Global Plan to End TB 2023-30 emphasises for the first time that detection of subclinical TB is a priority. WHO Systematic Screening guidelines (2021) have stressed the importance of CXR as a screening tool …

gb, ch, Afrique du Sud (code pays fourni par la source)

Diagnostic accuracy of Chest X-Ray Computer Aided Detection software and blood biomarkers for detection of prevalent and incident tuberculosis in household contacts followed up for 5 years

Liana Macpherson, Sandra V. Kik, Matteo Quartagno, Francisco Lakay et autres

Abstract Background WHO Tuberculosis (TB) screening guidelines recommend computer-aided detection (CAD) software for chest radiograph (CXR) interpretation. However, studies evaluating their diagnostic and prognostic accuracy are limited. Methods We conducted a prospective cohort study of household TB contacts in South Africa. Participants …

gb, ch, Afrique du Sud, us, au (code pays fourni par la source)