Invention of VH-937, a Potent HIV-1 Maturation Inhibitor with the Potential for Infrequent Oral Dosing in Humans
Sing‐Yuen Sit, Yan Chen, Jie Chen, Brian L. Venables et autres
8 citationsACS Medicinal Chemistry Letters
Li Xu
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14Publications signalées
857Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Inflammatory mediators and NSAID effectsSynthesis of β-Lactam CompoundsHIV Research and TreatmentHIV/AIDS drug development and treatmentSynthesis and biological activity
Publications récentes
Preclinical Profile of the HIV-1 Maturation Inhibitor VH3739937
Brian McAuliffe, Paul Falk, Jie Chen, Yan Chen et autres
2 citationsViruses
Atropisomerism Observed in Galactose-Based Monosaccharide Inhibitors of Galectin-3 Comprising 2-Methyl-4-phenyl-2,4-dihydro-3H-1,2,4-triazole-3-thione
David Yoon, Chunjian Liu, Prasada Rao Jalagam, Jianxin Feng et autres
4 citationsJournal of Medicinal Chemistry
Synthesis, Structure–Activity Relationships, and In Vivo Evaluation of Novel C-17 Amine Derivatives Based on GSK3640254 as HIV-1 Maturation Inhibitors with Broad Spectrum Activity
Richard A. Hartz, Li Xu, Sing‐Yuen Sit, Jie Chen et autres
4 citationsJournal of Medicinal Chemistry
Synthesis, Structure–Activity Relationships, and In Vivo Evaluation of Novel Tetrahydropyran-Based Thiodisaccharide Mimics as Galectin-3 Inhibitors
Li Xu, Richard A. Hartz, Brett R. Beno, Kaushik Ghosh et autres
27 citationsJournal of Medicinal Chemistry
Identification and Preclinical Evaluation of the Bicyclic Pyrimidine ?-Secretase Modulator BMS-932481
Kenneth M. Boy, Jason Guernon, Dmitry Zuev, Li Xu et autres
23 citationsACS Medicinal Chemistry Letters
Design and optimization of tricyclic gamma-secretase modulators
Jianliang Shi, Dmitry Zuev, Li Xu, Kimberley A. Lentz et autres
13 citationsBioorganic & Medicinal Chemistry Letters
A Novel Solid‐Phase Chlorinating Reagent for the Synthesis of Acyl Chlorides.
Guanglin Luo, Li Xu, Graham S. Poindexter
0 citationsChemInform
A novel solid-phase chlorinating reagent for the synthesis of acyl chlorides
Guanglin Luo, Li Xu, Graham S. Poindexter
27 citationsTetrahedron Letters
Etoricoxib (MK-0663): Preclinical Profile and Comparison with Other Agents That Selectively Inhibit Cyclooxygenase-2
Denis Riendeau, M. David Percival, Christine Brideau, S. Charleson et autres
462 citationsJournal of Pharmacology and Experimental Therapeutics
2-Pyridinyl-3-(4-methylsulfonyl)phenylpyridines: Selective and orally active cyclooxygenase-2 inhibitors
Richard W. Friesen, Christine Brideau, Chi Chung Chan, S. Charleson et autres
129 citationsBioorganic & Medicinal Chemistry Letters
STRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDE
X. Lee, A. Thompson, Z. Zhang, T.T.H. Hoa et autres
0 citationsWorldwide Protein Data Bank
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