X. Lee

Characterization of the secondary binding sites of Maclura pomifera agglutinin by glycan array and crystallographic analyses

Jonathan Huang, Zhijian Xu, Die Wang, Craig M. Ogata et autres

The Maclura pomifera agglutinin (MPA) recognizes the T-antigen disaccharide Galβ1,3GalNAc mainly through interaction of the α-GalNAc moiety with its primary site, but the interactions of the two flanking subsites A and B with aglycones and substituents other than Gal, respectively, are not …

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STRUCTURE OF THE LECTIN MPA COMPLEXED WITH T-ANTIGEN DISACCHARIDE

X. Lee, A. Thompson, Z. Zhang, T.T.H. Hoa et autres

Intrinsic molecular activities of the interferon-induced 2-5A-dependent RNase.

Bin Dong, Lei Xu, A. Zhou, Bret A. Hassel et autres

2-5A-dependent RNase (RNase L), a unique endoribonuclease that requires 5'-phosphorylated 2',5'-linked oligoadenylates (2-5A), functions in the molecular mechanism of interferon action. Because this enzyme is present at very low levels in nature, characterization and analysis have been limited. The molecular cloning of …

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