Bérengère Salomé

Targeting CMV-induced adaptive NK cells to improve immunotherapy outcomes in bladder cancer

Bérengère Salomé

Targeting CMV-induced adaptive NK cells to improve immunotherapy outcomes in bladder cancer

Bérengère Salomé

Targeting CMV-induced adaptive NK cells to improve immunotherapy outcomes in bladder cancer

Bérengère Salomé

Abstract B060: CMV-induced adaptive NK cell functions to improve bladder cancer patient outcomes

Bérengère Salomé, Igor Duquesne, Amber Barbini, Sonia Domingos Pereira et autres

Abstract INTRODUCTION Intravesical instillation of Bacillus Calmette Guérin (BCG) is the frontline therapy for high grade non-muscle invasive bladder cancer (NMIBC). However, 32-42% of patients experience recurrence and 13% progress to muscle-invasive disease. The immune system is shaped by lifelong virus exposures. …

us, ch, de (code pays fourni par la source)

Impact de l’infection à cytomégalovirus sur HLA-E tumoral et les cellules NK adaptatives et la réponse au BCG dans les tumeurs de vessie n’infiltrant pas le muscle

Igor Duquesne, Bérengère Salomé, Y. Haocheng, Bruce A. Hug et autres

fr, us, dk, ca (code pays fourni par la source)

IP14-18 CYTOMEGALOVIRUS INFECTION DRIVES TUMOR HUMAN LEUKOCYTE ANTIGEN E EXPRESSION AND PROMOTES ADAPTIVE NATURAL KILLER CELL FUNCTIONS IN HUMAN BLADDER CANCER

Brenda Hug, Igor Duquesne, Bérengère Salomé, Iyinyeoluwa Okulate et autres

The HLA-E/NKG2A axis identifies a therapeutic vulnerability in BCG-unresponsive bladder cancer

Bérengère Salomé, Haocheng Yu, Daniel L Ranti, Seungmin Bang et autres

ABSTRACT Background Bacillus Calmette-Guérin (BCG) is the standard of care treatment for high-risk non-muscle-invasive bladder cancer (NMIBC), yet many patients develop recurrent disease despite evidence of ongoing immune activation. We investigated mechanisms of immune escape in BCG-unresponsive tumors and evaluated the therapeutic …

us, dk, il, gb (code pays fourni par la source)

PEDIATRIC BURN MECHANISMS AND ITS PREVENTIONS: AN EPIDEMIOLOGICAL ANALYSISOF CHILDREN ADMITTED TO THE UHC MOHAMMED VI PLASTIC SURGERY DEPARTMENT IN MARRAKECH, MOROCCO

Mukhtar Hussain Sahir, Abdelaziz Marzak, Bérengère Salomé, c Benlaguide et autres

This study aims to describe the causes, mechanisms and characteristics of children burn injuries. It is a retrospective study that analyses the epidemiological particularities that are leading causes to burn injuries of a 100 cases of pediatric population and discuss different possible …

CARCINOMEEPIDERMOIDEDU SCALP:APROPOSDUNCASMULTI-COMPLIQUE.SQUAMOUSCELLCARCINOMAOFSCALP: ACASEREPORTOF APATIENT WITH MULTIPLE COMPLICATIONS

Mukhtar Hussain Sahir, a Marzak, Bérengère Salomé, c Benlaguide et autres

Squamous cell carcinoma of the scalp is frequent in our field of practice. Nevertheless, we report the case of a patient who had consulted at a locally advanced stage of the tumour. The patient was being monitored in our department and had …

Advanced diffusion-weighted MRI and proteomic analysis as potential predictors of renal tumor histopathology

Octavia Bane, Jorge Daza, Bérengère Salomé, John P. Sfakianos et autres

In this prospective, single-center study, we evaluated the use of intravoxel incoherent motion model of diffusion (IVIM-DWI) and high-throughput urine proteomics associated with inflammation for diagnosis and characterization of small renal masses. IVIM-DWI parameters had good to excellent diagnostic performance in identifying …

Data from Immunosuppressive Mediators Impair Proinflammatory Innate Lymphoid Cell Function in Human Malignant Melanoma

Giuseppe Ercolano, Andrea Garcia-Garijo, Bérengère Salomé, Alejandra Gomez‐Cadena et autres

Abstract Innate lymphoid cells (ILC) are a family of immune cells that are emerging as potent orchestrators of immune responses. In cancer, ILCs display both pro- and antitumorigenic functions depending on the nature of the tumor and the involved ILC subset. Little …

Data from Immunosuppressive Mediators Impair Proinflammatory Innate Lymphoid Cell Function in Human Malignant Melanoma

Giuseppe Ercolano, Andrea García-Garijo, Bérengère Salomé, Alejandra Gomez‐Cadena et autres

Abstract Innate lymphoid cells (ILC) are a family of immune cells that are emerging as potent orchestrators of immune responses. In cancer, ILCs display both pro- and antitumorigenic functions depending on the nature of the tumor and the involved ILC subset. Little …