Maura Strigini

ESA VIVALDI (1 & 2) campaigns: sex-specific bone responses to dry immersion-induced unloading

Peter Fernández, Marie‐Thérèse Linossier, Marie‐Pierre Bareille, Rebecca Billette de Villemeur et autres

Dry immersion induces rapid bone deconditioning in both sexes, but females show greater skeletal sensitivity to unloading, with stronger resorptive increases [tartrate-resistant acid phosphatase isoform 5b (TRAP5b), crosslinked C-terminal telopeptide of type I collagen (CTX)] and a more pronounced periosteal decline (periostin) …

fr (code pays fourni par la source)

Divergent Liver and Kidney Metabolic Responses to Ketogenic, High-Fat, and Sucrose-Enriched Diets in Mice

Giulia Grillo, Nathalie Véga, Agnieszka Zaczek, Anna Selmi et autres

BACKGROUND/OBJECTIVES: Feeding with a ketogenic diet (KD), nutritionally devoid of carbohydrates, may be metabolically beneficial. The administration of a KD to mice after previous feeding with a high-fat, high-carbohydrate diet (HFD) induced weight loss, ketonemia, and glycemic normalization. Here, to compare organ-specific …

fr, it, pl (code pays fourni par la source)

EFFECTS OF A KETOGENIC DIET ON THE PROGRESSION OF OSTEOARTHRITIS IN OBESE MICE - ARTICULAR, METABOLIC AND EPIGENETIC CHARACTERIZATION

Asmaa EL Maarbani, Maura Strigini, Thomas Solé, Nathalie Véga et autres

fr, de (code pays fourni par la source)

Ecdysone-mediated intestinal growth contributes to microbiota-driven developmental plasticity under malnutrition

Longwei Bai, Stéphanie Bellemin, Élodie Guillemot, Maura Strigini et autres

Organ and systemic growth must remain coordinated during development, even under nutritional stress. In Drosophila larvae, the intestinal microbiota contributes to this coordination by promoting growth and maturation under chronic undernutrition. Using gnotobiotic models, we show that association with Lactiplantibacillus plantarum (Lp) …

fr (code pays fourni par la source)

A Proposal for Monitoring of Bone Function in Microgravity and Analogues

Francesca Cosmi, Livia Visai, Laurence Vico, Maura Strigini et autres

cannot comprehensively assess skeletal integrity [3]. High-resolution micro-tomographic techniques enable detailed pre- and post-mission evaluation of trabecular bone, but are not suitable for longitudinal monitoring [4]. Mesoscale experiments and simulations under modeled microgravity highlight the need to complement traditional morpho-geometrical measures with …

Therapeutic potential of FGF19 in combatting osteosarcopenia: effects on muscle strength and bone health in aged male mice

Hao Zhang, Priyanka Garg, Bérengère Benoit, Claudie Pinteur et autres

Osteosarcopenia, characterized by the coexistence of osteopenia/osteoporosis and sarcopenia, represents a significant health concern in geriatrics, with an increased risk of falls and fractures. The enterokine fibroblast growth factor 19 (FGF19) was recently shown to prevent muscle weakness in preclinical models. This …

fr, no (code pays fourni par la source)

Resistance and Aerobic Preconditioning Delays Unloading‐Induced Multisystemic Physiological Changes: The NEBULA Project

Théo Fovet, Margot Issertine, Pauline Jacob, Stéphanie Ghislin et autres

Spaceflight is considered an extreme environment, and from the first days of flight, microgravity causes significant modifications in several physiological systems, particularly the musculoskeletal, cardiovascular, immunological, and nervous systems. To safeguard astronauts' health on upcoming trips, it is crucial to better counteract …

fr (code pays fourni par la source)

Author Reply to Peer Reviews of Drosophila larval gut transcriptome reveals a microbe-mediated intestinal tissue growth via Ecdysone during adaptive growth

Longwei Bai, Stéphanie Bellemin, Élodie Guillemot, Maura Strigini et autres

fr, nl (code pays fourni par la source)

The Impact of Ketogenic Nutrition on Obesity and Metabolic Health: Mechanisms and Clinical Implications

Marta Biesiekierska, Maura Strigini, Agnieszka Śliwińska, Luciano Pirola et autres

The ketogenic diet (KD) has recently gained increasing popularity. This high-fat, adequate-protein, and carbohydrate-poor eating pattern leads to nutritional ketosis. The KD has long been known for its antidiabetic and antiepileptic effects and has been used therapeutically in these contexts. Recently, the …

pl, fr (code pays fourni par la source)

Ecdysone-mediated intestinal growth contributes to microbiota-driven developmental plasticity under malnutrition

Longwei Bai, Élodie Guillemot, Maura Strigini, Benjamin Gillet et autres

Abstract Organ and systemic growth must remain coordinated during development, even under nutritional stress. In Drosophila larvae, the intestinal microbiota contributes to this coordination by promoting growth and maturation under chronic undernutrition. Using gnotobiotic models, we show that association with Lactiplantibacillus plantarum …

fr, nl (code pays fourni par la source)

Vivaldi: Exploring Bone Adaptation and Energy Metabolism between Males and Females Under Dry Immersion Conditions

Peter Fernández, Marie‐Thérèse Linossier, Christine Bonneau, Marie‐Pierre Bareille et autres

fr (code pays fourni par la source)

A surfactant lipid layer of endosomal membranes facilitates airway gas filling in Drosophila

Vasilios Tsarouhas, Dan Liu, Georgia Tsikala, Ylva Engström et autres

The mechanisms underlying the construction of an air-liquid interface in respiratory organs remain elusive. Here, we use live imaging and genetic analysis to describe the morphogenetic events generating an extracellular lipid lining of the Drosophila airways required for their gas filing and …

se, gr, bg, fr, de (code pays fourni par la source)