Nico De Lazzari

High‐Intensity Interval Training Boosts Immune Cells in Advanced Cancer Patients and Healthy Controls: Implications for Cancer Care

Fabian Kiehl, Nico De Lazzari, Ronja Beller, Isabella Deppe et autres

ABSTRACT Background Regular exercise improves quality of life (QoL) and reduces fatigue in advanced cancer patients (ACP), but acute immune responses are underexplored. This study investigated the effects of a single high‐intensity interval training (HIIT) session on natural killer (NK) cells and …

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Improving aerobic capacity in patients with advanced non-small cell lung cancer: study protocol of the 3-armed randomized controlled BREATH trial

Nico De Lazzari, Marcel Wiesweg, Miriam Götte, Jan Franco et autres

Abstract Background Lung cancer is one of the most common cancers in Germany, with around 56,000 new cases diagnosed in 2020. Approximately 65% are diagnosed at advanced stages, where symptoms such as fatigue, pain, dyspnea, and weight loss are prevalent. These patients …

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Consent, participation, and non-response in a registry-based survey of long-term cancer survivors in Germany

Kevin Claaßen, N. Sonuc, Nico De Lazzari, Jane Kersten et autres

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Improving aerobic capacity in patients with advanced non-small cell lung cancer: study protocol of the 3-armed randomized controlled BREATH trial

Nico De Lazzari, Marcel Wiesweg, Miriam Götte, Raluca Ileana Mincu et autres

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OPTILATER: optimal long-term survival after cancer – a cross-sectional study protocol for a quantitative survey on the care situation of long-term cancer survivors in Germany

Carl N. Martin, Nico De Lazzari, J. F. Kersten, Kevin Claaßen et autres

BACKGROUND: Cancer survivors in Germany face considerable challenges related to the late and long-term effects of treatment and a lack of post-treatment support. Despite an increasing number of cancer survivors, existing healthcare systems are insufficiently adapted to meet their ongoing needs, particularly …

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The impact of a single HIIT intervention on the mobilization of NK cells and ILCs in adolescents and young adults (AYA) undergoing cancer treatment: an interventional controlled trial

Isabella Deppe, Ronja Beller, Fabian Kiehl, Nico De Lazzari et autres

Abstract Objective The study investigated the response of immune cells, particularly natural killer (NK) cells and innate lymphoid cells (ILCs), to acute exercise in adolescents and young adults (AYAs) undergoing cancer treatment, to lower their treatment burden and evaluate the value of …

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Immune response to an acute exercise session in patients with advanced cancer in comparison to a healthy control group

Fabian Kiehl, Nico De Lazzari, Ronja Beller, Isabella Deppe et autres

Hintergrund Patients with advanced cancer (ACP) undergoing palliative chemotherapeutic treatment suffer from systemic inflammation. Natural killer cells (NK cells) are very effective at fighting tumor-associated inflammation. The role of exercise as a supportive therapy in cancer treatment and its positive long-term effects …

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P-move: a randomized control trial of exercise in patients with advanced pancreatic or biliary tract cancer (aPBC) receiving beyond first-line chemotherapy

Nico De Lazzari, Miriam Götte, Stefan Kasper, Eileen Meier et autres

PURPOSE: Patients with advanced pancreatic and biliary tract cancer (aPBC) frequently suffer from high symptom burden. Exercise can reduce treatment side effects and improve patient-related outcomes (PROMs). However, evidence from prospective studies regarding feasibility and efficacy in advanced settings are sparse. The …

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P-move: a randomized control trial of exercise in patients with advanced pancreatic or biliary tract cancer (aPBC) receiving beyond first-line chemotherapy

Nico De Lazzari, Miriam Götte, Stefan Kasper, Eileen Meier et autres

Abstract Purpose Patients with advanced pancreatic and biliary tract cancer (aPBC) frequently suffer from high symptom burden. Exercise can reduce treatment side effects and improve patient-related outcomes (PROMs). However, evidence from prospective studies regarding feasibility and efficacy in advanced settings are sparse. …

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Entwicklung einer KI-gestützten Bewegungstherapie bei onkologischen Palliativpatienten

Nico De Lazzari, Felix Wichum, Miriam Götte, Corinna David et autres

Zusammenfassung HintergrundDie wechselnde Symptomlast ist eine große Hürde in der Sporttherapie von onkologischen Palliativpatienten. Die täglich variierende Symptomstärke erschwert die Einstellung einer optimalen Trainingsbelastung und stellt neben der Motivation eine große Barriere für die Teilnahme an bewegungstherapeutischen Interventionen dar. Ein durch Künstliche …

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Development of an AI-supported exercise therapy for advanced cancer patients

Felix Wichum, Nico De Lazzari, Miriam Götte, Corinna David et autres

Abstract Exercise therapy is able to reduce symptom burden in advanced cancer patients (ACP). However, ACP daily form differs between days e.g. tumor and therapy induced. We included five ACP to classify individual exercise capacity due to cardiovascular parameters. Features are extracted …

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A Systematic Review of the Safety, Feasibility and Benefits of Exercise for Patients with Advanced Cancer

Nico De Lazzari, Timo Niels, Mitra Tewes, Miriam Götte

Exercise therapy is a common supportive strategy in curative cancer treatment with strong evidence regarding its positive effects on, for example, cancer-related fatigue, health- related quality of life, and physical function. In the field of advanced cancer patients, knowledge about exercise as …

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