Mitra Tewes

Test-Retest Reliability of Smartwatch-Derived Features for Longitudinal Monitoring: An Observational Cohort Study (Preprint)

Hans Lennard Schneidewind, Tim Fellerhoff, Jan Franco, Mitra Tewes et autres

BACKGROUND Smartwatches are increasingly used for decentralized data collection in clinical research, but the everyday-life settings that make these data attractive also introduce variability. Before a smartwatch-derived feature can support clinical monitoring, its reproducibility must be established: features with low test-retest reliability …

High‐Intensity Interval Training Boosts Immune Cells in Advanced Cancer Patients and Healthy Controls: Implications for Cancer Care

Fabian Kiehl, Nico De Lazzari, Ronja Beller, Isabella Deppe et autres

ABSTRACT Background Regular exercise improves quality of life (QoL) and reduces fatigue in advanced cancer patients (ACP), but acute immune responses are underexplored. This study investigated the effects of a single high‐intensity interval training (HIIT) session on natural killer (NK) cells and …

de (code pays fourni par la source)

How is access to palliative care negotiated and accomplished among Muslim immigrants and their direct descendants in Germany, and what culturally and religiously framed narrative resources shape meaning-making in serious illness and approaching death? A multicentre four-group qualitative study using constructivist Grounded theory and Narrative inquiry

Florian Bernhardt, Ferya Banaz‐Yaşar, María Rosa Salvador Comino, T Altscher et autres

Background Muslim immigrants and their direct descendants are a large ethnoreligious minority in many regions, yet their access to palliative care remains under-researched and poorly theorised for practice. Existing evidence points to structural, communicative and cultural constraints, while mechanisms at the threshold …

de (code pays fourni par la source)

Correction: Schmitz et al. Validation of the Palliative Care and Rapid Emergency Screening (P-CaRES) Tool in Germany. J. Clin. Med. 2025, 14, 2191

Julia Schmitz, Mitra Tewes, Baicy Mathew, Marie Bubel et autres

In the original publication [...].

de (code pays fourni par la source)

Improving aerobic capacity in patients with advanced non-small cell lung cancer: study protocol of the 3-armed randomized controlled BREATH trial

Nico De Lazzari, Marcel Wiesweg, M Götte, Jan Franco et autres

Abstract Background Lung cancer is one of the most common cancers in Germany, with around 56,000 new cases diagnosed in 2020. Approximately 65% are diagnosed at advanced stages, where symptoms such as fatigue, pain, dyspnea, and weight loss are prevalent. These patients …

de (code pays fourni par la source)

Improving aerobic capacity in patients with advanced non-small cell lung cancer: study protocol of the 3-armed randomized controlled BREATH trial

Nico De Lazzari, Marcel Wiesweg, Miriam Götte, Raluca Mincu et autres

de (code pays fourni par la source)

Randomized Investigation of Heart Failure Therapy in Patients with Advanced Cancer at Risk of Cardiac Wasting: Rationale and Design of the EMPATICC Trial

Markus S. Anker, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes et autres

AIMS: End-stage cancer may resemble a heart failure (HF)-like phenotype marked by cardiac wasting, dysfunction, and symptoms such as dyspnoea, congestion, and impaired physical function. The EMPATICC (EMPower the heArt of patients with TermInal Cancer using Cardiac medicines) trial evaluates the safety …

de, gb, us, hu (code pays fourni par la source)

Heart failure therapy in patients with advanced cancer receiving specialized palliative care (EMPATICC trial)

Markus S. Anker, Amir A. Mahabadi, Matthias Totzeck, Mitra Tewes et autres

BACKGROUND AND AIMS: Advanced cancer may resemble a heart failure (HF)-like phenotype marked by cardiac wasting, dyspnoea, congestion, and/or physical dysfunction. The trial evaluated safety and efficacy of HF therapy among patients with advanced cancer receiving specialized palliative care to improve patients' …

de, gb, us, ch, cl, hu (code pays fourni par la source)

Optimized heart failure therapy in patients with very advanced cancer in palliative care: dosing strategies from the EMPATICC trial

Markus S. Anker, Sven Bercker, Michael Böhm, Bela Merkely et autres

Cardiac wasting occurs in patients with end-stage cancer, leading to the development of heart failure (HF)-like symptoms characterized by dyspnea, reduced physical function, and diminished quality of life. The EMPATICC (EMPower the heArt of patients with TermInal Cancer using Cardiac medicines) is …

de, hu, us, pk (code pays fourni par la source)

Resistance training in cachectic pancreatic and lung cancer patients: randomised controlled trial

Timo Niels, Lisa Stich, Stefanie Siebert, Nico DeLazzari et autres

OBJECTIVES: Pancreatic and lung cancer are associated with cancer cachexia (CC), which negatively impacts patients' quality of life, treatment outcomes and prognosis. This study aimed to evaluate the feasibility and effectiveness of a 24-week eccentrically overloaded resistance training (ERT) in patients with …

de (code pays fourni par la source)

Abstract P5-04-19: Gene variants in circulating tumor cells as markers of resistance in patients with metastatic breast cancer receiving CDK4/6 inhibitors

Sabine Kasimir‐Bauer, Stefanos Ioannis Moukas, Hans‐Christian Kolberg, Mitra Tewes et autres

Abstract Background: Predictive biomarkers for the stratification of patients with metastatic (M), hormone receptor-positive/HER2-negative (HR+/HER2-) breast cancer (BC) to receive CDK4/6 inhibitor (i) treatment before therapy start are still missing to protect patients with primary resistant disease from starting ineffective therapies and …

Validation of the Palliative Care and Rapid Emergency Screening (P-CaRES) Tool in Germany

Julia Schmitz, Mitra Tewes, Marie Bubel, Clemens Kill et autres

Background/Objectives: The “Palliative Care and Rapid Emergency Screening Tool” (P-CaRES) is used to identify patients with palliative needs in the emergency department. This study aims to translate, adapt, and validate the P-CaRES tool for the German healthcare context. Methods: This is a …

de (code pays fourni par la source)