Camilla Cividini

Brain age prediction in generalized anxiety disorder using a convolutional neural network

Corey Richier, André Zugman, Anita Harrewijn, Elise M. Cardinale et autres

Higher predicted brain age difference has been associated with several psychiatric disorders. Generalized anxiety disorder (GAD) is associated with markers of accelerated aging. In this study, we determined brain predicted age difference (PAD) in individuals with GAD and healthy controls (HC) as …

Brain age prediction in generalized anxiety disorder using a convolutional neural network

Corey Richier, André Zugman, Anita Harrewijn, Elise M. Cardinale et autres

Higher predicted brain age difference has been associated with several psychiatric disorders. Generalized anxiety disorder (GAD) is associated with markers of accelerated aging. In this study, we determined brain predicted age difference (PAD) in individuals with GAD and healthy controls (HC) as …

us, cz, nl, de, es, br, dk, it, rs, gb, Afrique du Sud (code pays fourni par la source)

Artificial Intelligence, LLM-based generation of synthetic patients with Parkinson’s Disease: towards a digital twin paradigm for in silico studies

Emilio Merlo Pich, O Pomponio, Maria Antonietta Magno, Michele Berti et autres

Abstract Heterogeneity in sporadic Parkinson’s Disease (PD) is a critical problem that drives variable rates of progression and treatment response and complicates clinical trials. Access to large PD datasets that may help in clustering this heterogeneity is restricted by privacy and regulatory …

it (code pays fourni par la source)

Brain Age Prediction in Generalized Anxiety Disorder using a Convolutional Neural Network

Corey Richier, André Zugman, Anita Harrewijn, Elise M. Cardinale et autres

us, nl, de, es, br, it, rs, jp, gb, cz, Afrique du Sud (code pays fourni par la source)

Brain-based classification of youth with anxiety disorders: transdiagnostic examinations within the ENIGMA-Anxiety database using machine learning

Willem B. Bruin, Paul Zhutovsky, Guido Alexander van Wingen, Janna Marie Bas‐Hoogendam et autres

nl, Afrique du Sud, de, us, it, se, jp, dk, es, br, au, be, no, gb, rs, kr, cn (code pays fourni par la source)

Caudate functional networks influence brain structural changes with aging

Silvia Basaia, Matteo Zavarella, Giulia Rugarli, Giacomo Sferruzza et autres

Abstract Neurogenesis decline with aging may be associated with brain atrophy. Subventricular zone neuron precursor cells possibly modulate striatal neuronal activity via the release of soluble molecules. Neurogenesis decay in the subventricular zone may result in structural alterations of brain regions connected …

it (code pays fourni par la source)

EEG Correlates in the 3 Variants of Primary Progressive Aphasia

Giordano Cecchetti, Silvia Basaia, Elisa Canu, Camilla Cividini et autres

BACKGROUND AND OBJECTIVES: The 3 clinical presentations of primary progressive aphasia (PPA) reflect heterogenous neuropathology, which is difficult to be recognized in vivo. Resting-state (RS) EEG is promising for the investigation of brain electrical substrates in neurodegenerative conditions. In this study, we …

it (code pays fourni par la source)

Structural and Functional Brain Network Connectivity at Different King's Stages in Patients With Amyotrophic Lateral Sclerosis

Edoardo Gioele Spinelli, Alma Ghirelli, Silvia Basaia, Elisa Canu et autres

BACKGROUND AND OBJECTIVES: There is currently no validated disease-stage biomarker for amyotrophic lateral sclerosis (ALS). The identification of quantitative and reproducible markers of disease stratification in ALS is fundamental for study design definition and inclusion of homogenous patient cohorts into clinical trials. …

it (code pays fourni par la source)

EEG correlates in the three variants of Primary Progressive Aphasia

Giordano Cecchetti, Federica Agosta, Silvia Basaia, Camilla Cividini et autres

Abstract Background The analysis of EEG cortical sources is promising for the investigation of neurodegenerative disorders. The aim of this study is to explore its value in the characterization of the three clinical presentations of primary progressive aphasia (PPA). Method A resting‐state …

it (code pays fourni par la source)

Modeling pathological spread through the structural connectome in the FTLD spectrum

Federica Agosta, Silvia Basaia, Federica Facente, Camilla Cividini et autres

Abstract Background To explore the relationship between network vulnerability and longitudinal atrophy progression in FTLD spectrum, using Network Diffusion Model (NDM) of pathology spread. Method Thirty‐four behavioural‐variant frontotemporal dementia (bvFTD), 11 semantic‐variant primary progressive aphasia (svPPA) and 11 nonfluent/agrammatic‐variant primary progressive aphasia …

it (code pays fourni par la source)

Age-related vulnerability of the human brain connectome

Massimo Filippi, Camilla Cividini, Silvia Basaia, Edoardo Gioele Spinelli et autres

Multifactorial models integrating brain variables at multiple scales are warranted to investigate aging and its relationship with neurodegeneration. Our aim was to evaluate how aging affects functional connectivity of pivotal regions of the human brain connectome (i.e., hubs), which represent potential vulnerability …

it (code pays fourni par la source)

Altered Functional Connectivity of the Subthalamic Nucleus in Parkinson’s Disease: Focus on Candidates for Deep Brain Stimulation

Luigi Albano, Federica Agosta, Silvia Basaia, Camilla Cividini et autres

BACKGROUND: The hypothesis that the effectiveness of deep brain stimulation (DBS) in Parkinson's disease (PD) would be related to connectivity dysfunctions between the site of stimulation and other brain regions is growing. OBJECTIVE: To investigate how the subthalamic nucleus (STN), the most …

it, rs (code pays fourni par la source)