Giacomo Sferruzza

Navigating the Artificial Intelligence Revolution in Clinical Neurology: A New Multidisciplinary Task Force Within the European Academy of Neurology

Alice Accorroni, Raphael Wurm, Roland Wiest, Marcello Ienca et autres

BACKGROUND: Artificial intelligence (AI) is rapidly transforming clinical neurology, offering significant potential to enhance diagnosis, treatment, and disease management. Despite this transformative promise, AI adoption in neurology remains limited due to a lack of a reliable evidence base to support its use, …

us, at, ch, de, it, gb, fr (code pays fourni par la source)

Author Correction: OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours

Luojia Yang, Paul Renauer, Kaiyuan Tang, Joshua Saskin et autres

us, jp (code pays fourni par la source)

Gaps in the access to endovascular thrombectomy for acute ischaemic stroke: estimating neurointerventional training needs and modelling implementation impact based on current thrombectomy indicators.

Adnan Mujanović, Michele Romoli, Giacomo Sferruzza, Alice Accorroni et autres

Introduction Endovascular therapy (EVT) has become an increasingly important part of acute stroke management. However, the lack of trained neurointerventionalists represents a key barrier in expanding availability of EVT in Europe. This project aimed to investigate the association between the number of …

at (code pays fourni par la source)

Gaps in the access to endovascular thrombectomy for acute ischaemic stroke: estimating neurointerventional training needs and modelling implementation impact based on current thrombectomy indicators

Adnan Mujanović, Michele Romoli, Giacomo Sferruzza, Alice Accorroni et autres

INTRODUCTION: Endovascular therapy (EVT) has become an increasingly important part of acute stroke management. However, the lack of trained neurointerventionalists represents a key barrier in expanding availability of EVT in Europe. This project aimed to investigate the association between the number of …

ch, at, it, us, ro, es, de, gb, dk, no, gr, fr, pt (code pays fourni par la source)

Abstract 5187: IL-21-Enhanced NK cells: A mitochondrial fitness enhancement for targeting glioblastoma stem cells

Mayra Shanley, Sufang Li, Mandira Manandhar, Giacomo Sferruzza et autres

Abstract Glioblastoma (GBM), an aggressive brain cancer, recurs due to the resistance of glioblastoma stem cells (GSCs) to conventional therapies. We recently showed that cord blood-derived NK cells (CBNK) armed with cytokines like IL-21 exhibit enhanced anti-tumor activity against GSCs, showing superior …

us (code pays fourni par la source)

Epigenetic biomarkers of progestin-resistance in endometriosis

E. Cansu Cevik, Ramanaiah Mamillapalli, Giacomo Sferruzza, Padmavathi Mamillapalli et autres

OBJECTIVE: Endometriosis is a heterogeneous, estrogen-dependent inflammatory disorder that affects up to 15% of reproductive age women. Progestin-based therapies are the most commonly prescribed initial treatment; however, approximately one-third of patients exhibit progestin resistance, leading to inadequate symptom relief and discontinuation. Given …

us (code pays fourni par la source)

OR7A10 GPCR engineering boosts CAR-NK therapy against solid tumours

Luojia Yang, Paul Renauer, Kaiyuan Tang, Josh Saskin et autres

us, jp (code pays fourni par la source)

P0355 Prevalence of malnutrition and sarcopenia in hospitalized patients with inflammatory bowel diseases: a multimodal cross-sectional study

E Bracciamà, S Cimminisi, S Zimbardo, C Amari et autres

Abstract Background Malnutrition and sarcopenia are increasingly recognized as frequent and clinically relevant complications in inflammatory bowel disease (IBD). Recent studies have reported malnutrition rates up to 65–75% and sarcopenia prevalence as high as 70%, both conditions being associated with higher hospitalization …

es (code pays fourni par la source)

A collaborative future: EAN RRFS and Polish young neurologists at the RRFS Representative meeting in Warsaw

Aleksandra Pietruczuk, Alicia González‐Martínez, Alice Accorroni, Isabella Colonna et autres

pl, es, it, ru, nl (code pays fourni par la source)

Assessing time-trend bias in glioblastoma prognosis over 2 decades of clinical trials

Giacomo Sferruzza, Karthik Desingu, Antônio Cesar Marques da Costa Cruz, Gaetano Finocchiaro

BACKGROUND: The time-trend bias represents a potential limitation in the use of external controls in glioblastoma (GBM) trials. In this study, we assessed whether outcomes for newly diagnosed GBM (ndGBM) patients treated with the standard Stupp protocol in clinical trials have changed …

it, Afrique du Sud, us (code pays fourni par la source)

T.04.10 EATING DISORDERS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES: RELATIONSHIP WITH PSYCHOLOGICAL CHARACTERISTICS

Emanuele Bracciamà, S. Cimminisi, Angelo Milano, Giacomo Sferruzza et autres

Perceived discrepancies in neurosonology training and certification across Europe: a RRFS/EAN survey

Vlad Tiu, João Durães, Francesco Di Lorenzo, Nina Vashchenko et autres

Introduction: Neurosonology is a vital paraclinical investigation in modern neurology. However, access to education and certification in neurosonology for neurology residents and young specialists in Europe is challenging, and comprehensive data regarding this topic are scarce. Information regarding difficulties in neurosonology training …

ro, pt, it, dk, es (code pays fourni par la source)