Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5, and OSM
Ravi V. Shah, Hannah G. Polikowsky, Mariaelisa Graff, Eric R. Gamazon et autres
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0 citations
UNC Libraries
Jungkyun Seo
Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.
21Publications signalées
254Citations signalées
2Affiliations récentes
Les institutions déclarées
Les domaines associés
Chronic Obstructive Pulmonary Disease (COPD) ResearchGenetic Associations and EpidemiologyGenomics and Chromatin DynamicsInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisAsthma and respiratory diseases
Les publications récentes
Multi-ancestry genome-wide association study and meta-analysis of lung function decline
Bonnie Patchen, Jingwen Zhang, Nathan Gaddis, Traci M. Bartz et autres
BACKGROUND: Despite evidence for a genetic component, few genetic associations with lung function decline have been identified. We aimed to evaluate genome-wide associations and putative downstream functionality of genetic variants for lung function decline. METHODS: We conducted genome-wide association study (GWAS) analyses …
us, gb, kr, tw, ca (code pays fourni par la source)
0 citations
Respiratory Research
Additional file 1 of Multi-ancestry genome-wide association study and meta-analysis of lung function decline
Bonnie Patchen, Jingwen Zhang, Nathan Gaddis, Traci M. Bartz et autres
Supplementary Material 1.
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0 citations
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Multi-ancestry genome-wide association study and meta-analysis of lung function decline
Bonnie Patchen, Jingwen Zhang, Nathan Gaddis, Traci M. Bartz et autres
Abstract Background Despite evidence for a genetic component, few genetic associations with lung function decline have been identified. We aimed to evaluate genome-wide associations and putative downstream functionality of genetic variants for lung function decline. Methods We conducted genome-wide association study (GWAS) …
us, gb, kr, ca (code pays fourni par la source)
0 citations
Figshare
Additional file 2 of Multi-ancestry genome-wide association study and meta-analysis of lung function decline
Bonnie Patchen, Jingwen Zhang, Nathan Gaddis, Traci M. Bartz et autres
Supplementary Material 2.
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0 citations
Figshare
Additional file 2 of Multi-ancestry genome-wide association study and meta-analysis of lung function decline
Bonnie Patchen, Jingwen Zhang, Nathan Gaddis, Traci M. Bartz et autres
Supplementary Material 2.
us, gb, kr, ca (code pays fourni par la source)
0 citations
Figshare
Multi-ancestry genome-wide association study and meta-analysis of lung function decline
Bonnie Patchen, Jingwen Zhang, Nathan Gaddis, Traci M. Bartz et autres
Abstract Background Despite evidence for a genetic component, few genetic associations with lung function decline have been identified. We aimed to evaluate genome-wide associations and putative downstream functionality of genetic variants for lung function decline. Methods We conducted genome-wide association study (GWAS) …
us, gb, kr, ca (code pays fourni par la source)
0 citations
Figshare
Additional file 1 of Multi-ancestry genome-wide association study and meta-analysis of lung function decline
Bonnie Patchen, Jingwen Zhang, Nathan Gaddis, Traci M. Bartz et autres
Supplementary Material 1.
us, gb, kr, ca (code pays fourni par la source)
0 citations
Figshare
Multiomics reveal key inflammatory drivers of severe obesity: IL4R, LILRA5, and OSM
Hung‐Hsin Chen, Heather M. Highland, Eitan Frankel, Alyssa Scartozzi et autres
Polygenic severe obesity (body mass index [BMI] ≥40 kg/m 2 ) has increased, especially in Hispanic/Latino populations, yet we know little about the underlying mechanistic pathways. We analyzed whole-blood multiomics data to identify genes differentially regulated in severe obesity in Mexican Americans …
us, tw, kr, gb, mx (code pays fourni par la source)
8 citations
Cell Genomics
Genetic and transcriptomic landscape of colonic diverticulosis
Temitope O. Keku, Hongwei Liu, Jungkyun Seo, Robert S. Sandler et autres
OBJECTIVE: Colonic diverticulosis is a prevalent condition among older adults, marked by the presence of thin-walled pockets in the colon wall that can become inflamed, infected, haemorrhage or rupture. We present a case-control genetic and transcriptomic study aimed at identifying the genetic …
us (code pays fourni par la source)
0 citations
Carolina Digital Repository (University of North Carolina at Chapel Hill)
Exploiting meta-analysis of genome-wide interaction with serum 25-hydroxyvitamin D to identify novel genetic loci associated with pulmonary function
Jungkyun Seo, Nathan Gaddis, Bonnie Patchen, Jiayi Xu et autres
Background Higher 25-hydroxyvitamin D (25(OH)D) concentrations in serum has a positive association with pulmonary function . Investigating genome-wide interactions with 25(OH)D may reveal new biological insights into pulmonary function. Objectives We aimed to identify novel genetic variants associated with pulmonary function by …
us, ca (code pays fourni par la source)
1 citation
American Journal of Clinical Nutrition
Genetic and transcriptomic landscape of colonic diverticulosis
Jungkyun Seo, Hongwei Liu, Kristin L. Young, Xinruo Zhang et autres
Objective Colonic diverticulosis is a prevalent condition among older adults, marked by the presence of thin-walled pockets in the colon wall that can become inflamed, infected, haemorrhage or rupture. We present a case–control genetic and transcriptomic study aimed at identifying the genetic …
us (code pays fourni par la source)
12 citations
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