Laura S. Smallcomb

Effectiveness of Maternal Vaccination with mRNA COVID-19 Vaccine During Pregnancy Against COVID-19–Associated Hospitalization in Infants Aged <6 Months — 17 States, July 2021–January 2022

Elizabeth H. Mack, Katherine Irby, Kathleen Chiotos, Tamara T. Bradford et autres

COVID-19 vaccination is recommended for persons who are pregnant, breastfeeding, trying to get pregnant now, or who might become pregnant in the future, to protect them from COVID-19.§ Infants are at risk for life-threatening complications from COVID-19, including acute respiratory failure (1). …

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BNT162b2 mRNA Vaccination Against Coronavirus Disease 2019 is Associated With a Decreased Likelihood of Multisystem Inflammatory Syndrome in Children Aged 5–18 Years—United States, July 2021 – April 2022

Stephanie P. Schwartz, Amber O. Orzel, Kelly Nicole Michelson, Adrienne G. Randolph et autres

BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C), linked to antecedent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is associated with considerable morbidity. Prevention of SARS-CoV-2 infection or coronavirus disease 2019 (COVID-19) by vaccination might also decrease MIS-C likelihood. METHODS: In a …

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Factors Associated With COVID-19 Non-vaccination in Adolescents Hospitalized Without COVID-19

Katherine Bline, Sabrina M. Heidemann, Manish M Patel, Tracie C. Walker et autres

BACKGROUND: Pfizer-BioNTech COVID-19 vaccine received emergency use authorization for persons ≥ 16 years in December 2020 and for adolescents 12-15 years in May 2021. Despite the clear benefits and favorable safety profile, vaccine uptake in adolescents has been suboptimal. We sought to …

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373: A CASE OF PEDIATRIC AUTORESUSCITATION COMPLICATING ORGAN DONATION AFTER CARDIAC DEATH

Laura S. Smallcomb, Jessica M. Turnbull, Brian Tinch

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1195: ASSESSMENT OF HYPEROXIA FREQUENCY IN A QUATERNARY CARE PEDIATRIC ICU: FIRST STEP TOWARD NORMOXIA

Laura S. Smallcomb, Jennifer Laws, Michael D. Santarelli, Katharine Boyle

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Maternal Vaccination and Risk of Hospitalization for Covid-19 Among Infants

Natasha Halasa, Samantha M. Olson, Mary Allen Staat, Margaret M. Newhams et autres

(Abstracted from N Engl J Med 2022;387:109–119) COVID-19 during pregnancy is associated with a greater risk of adverse pregnancy outcomes and neonatal complications. Studies have shown that mRNA vaccines are highly effective in preventing severe COVID-19 during pregnancy, and the Centers for …

A rare case of neonatal meningoencephalitis from Paenibacillus thiaminolyticus

Laura S. Smallcomb, Terry C. Dixon, Kamran N. Azad, Whitney Marvin

Paenibacillus infections can be life threatening and are being reported with increasing incidence. There are only a few case reports of infections and are mainly described in patients who are immunocompromised, injection drug users, or those with prosthetic devices. Due to improved …

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Factors Associated With COVID-19 Non-vaccination in Adolescents Hospitalized Without COVID-19

Leila C. Sahni, Ashley M. Price, Samantha M. Olson, Margaret M. Newhams et autres

BACKGROUND: Pfizer-BioNTech COVID-19 vaccine received emergency use authorization for persons ≥ 16 years in December 2020 and for adolescents 12-15 years in May 2021. Despite the clear benefits and favorable safety profile, vaccine uptake in adolescents has been suboptimal. We sought to …

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Tachyarrhythmias During Hospitalization for COVID‐19 or Multisystem Inflammatory Syndrome in Children and Adolescents

Audrey Dionne, Kevin G. Friedman, Cameron C. Young, Margaret M. Newhams et autres

Background Cardiac complications related to COVID-19 in children and adolescents include ventricular dysfunction, myocarditis, coronary artery aneurysm, and bradyarrhythmias, but tachyarrhythmias are less understood. The goal of this study was to evaluate the frequency, characteristics, and outcomes of children and adolescents experiencing …

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BNT162b2 mRNA Vaccination Against Coronavirus Disease 2019 is Associated With a Decreased Likelihood of Multisystem Inflammatory Syndrome in Children Aged 5–18 Years—United States, July 2021 – April 2022

Margaret M. Newhams, Samantha M. Olson, Natasha Halasa, Ashley M. Price et autres

BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C), linked to antecedent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is associated with considerable morbidity. Prevention of SARS-CoV-2 infection or coronavirus disease 2019 (COVID-19) by vaccination might also decrease MIS-C likelihood. METHODS: In a …

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Maternal Vaccination and Risk of Hospitalization for Covid-19 among Infants

Natasha Halasa, Samantha M. Olson, Mary Allen Staat, Margaret M. Newhams et autres

BACKGROUND: Infants younger than 6 months of age are at high risk for complications of coronavirus disease 2019 (Covid-19) and are not eligible for vaccination. Transplacental transfer of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) after maternal Covid-19 vaccination may …

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Life-Threatening Complications of Influenza vs Coronavirus Disease 2019 (COVID-19) in US Children

Natasha Halasa, Andrew J. Spieker, Cameron C. Young, Samantha M. Olson et autres

BACKGROUND: Clinical differences between critical illness from influenza infection vs coronavirus disease 2019 (COVID-19) have not been well characterized in pediatric patients. METHODS: We compared demographics, clinical characteristics, and outcomes of US children (aged 8 months to 17 years) admitted to the …

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