Accès ouvert
2026
article
OpenAlex
Ciara Loughrey, Juliana B. T. Carnielli, Shoumit Dey, Helen M. Ashwin et autres
Abstract Visceral leishmaniasis (VL) is a life-threatening parasitic disease caused by Leishmania donovani and L. infantum . Although VL is characterised by organ-specific immunopathology and parasitism of the spleen, liver and bone marrow, other tissues may harbour parasites without overt pathology. The …
gb
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Accès ouvert
2026
article
OpenAlex
Jadie Acklam, Sukhveer K. Mann, Karen Hogg, Richard Leach et autres
Here, we present a protocol for identifying human innate lymphoid cells (ILCs) and T cells using a 19-plex flow cytometry panel. We describe steps for titrating antibodies, preparing single-stain controls and samples, and staining cells for human peripheral blood and bone marrow …
gb
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Accès ouvert
2026
article
OpenAlex
Karen Hogg, Grant M. Calder, Alastair Droop, Ming Yang et autres
Background Brain metastasis occurs in approximately 16% of metastatic breast cancer patients, and incidence is increasing. Patients with breast cancer brain metastases frequently develop neurological problems including cognitive impairments and seizures. We previously demonstrated accumulation of activated microglia around the tumour site …
gb
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Accès ouvert
2026
article
OpenAlex
Ayenew Addisu, Alice Bayiyana, João Mário Campos Meireles da Cunha, Daniel Matano et autres
BACKGROUND: Visceral leishmaniasis (VL) is the most severe form of leishmaniasis, with East Africa accounting for ~70% of global burden. It primarily affects malnourished children, young adults, and HIV co-infected individuals. Clinical outcomes range from asymptomatic to fatal, with relapse mostly linked …
Éthiopie, Ouganda, gb, Kenya, de
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Accès ouvert
2026
article
OpenAlex
Usmaan Razzaq, Kieran F. Docherty, Alhussain Al Ajmi, Ali Alebraheem et autres
OBJECTIVE: Heart failure (HF) is common with high associated morbidity and mortality. UK National Institute for Health and Clinical Excellence (NICE) Guidelines suggest prioritising assessment by natriuretic peptide (NP) level, with patients with high NP levels assessed within 2 weeks. We evaluated …
gb
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Accès ouvert
2026
article
OpenAlex
Paul K. Wallace, Evan R. Jellison, Sherry Thornton, Kathleen Kluepfel et autres
joint effort begun in 2018 and continued in 2019 by Kamila Czechowska proved to be a valuable reference [1,2].Building on that spirit, we present summaries from CYTO 2025, held in Denver, Colorado, from May 31 to June 4.This manuscript serves as a …
us, uy, ca, de, au, nl
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Accès ouvert
2025
article
OpenAlex
Paul K. Wallace, Evan R. Jellison, Sherry Thornton, Kathleen Kluepfel et autres
joint effort begun in 2018 and continued in 2019 by Kamila Czechowska proved to be a valuable reference [1,2].Building on that spirit, we present summaries from CYTO 2025, held in Denver, Colorado, from May 31 to June 4.This manuscript serves as a …
us, gb, de, uy, be, ca, in, dk, es, nl, au, nz, ch, pt
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Ciara F. Loughrey, Juliana B. T. Carnielli, Shoumit Dey, Helen M. Ashwin et autres
Abstract Visceral leishmaniasis (VL) is a life-threatening parasitic disease caused by Leishmania donovani and L. infantum . Although VL is characterised by organ-specific immunopathology and parasitism of the spleen, liver and bone marrow, other tissues may harbour parasites without overt pathology. The …
gb
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Grace B. Hatton, Sally R. James, Andrew S. Mason, Richard T. Gawne et autres
Carcinogenesis in human urothelium is driven by a high burden of mutations caused by the antiviral "APOBEC3" (apolipoprotein B mRNA editing enzyme, catalytic subunit-like 3) cytosine deaminase enzymes; however, there is no established viral etiology. BK polyomavirus (BKPyV) is a ubiquitous childhood …
gb, us
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Accès ouvert
2025
preprint
OpenAlex
Ayenew Addisu, Alice Bayiyana, João Vieira da Cunha, Daniel Matano et autres
Abstract Background Visceral leishmaniasis (VL) is the most severe form of leishmaniasis, with East Africa accounting for ∼70% of global burden. It primarily affects malnourished children, young adults, and HIV co-infected individuals. Clinical outcomes range from asymptomatic to fatal, with relapse mostly …
Éthiopie, Ouganda, gb, Kenya, de
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
L. F. Wiggins, Jodie R. Malcolm, Karen Hogg, Peter J O’Toole et autres
Abstract Understanding how cancer-stromal interactions shape cancer progression requires tools that can capture dynamic phenotypic changes in physiologically relevant conditions. Traditional approaches for studying co-culture interactions, such as transcriptomics and flow cytometry, provide valuable insights but are limited by their static nature …
gb
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Accès ouvert
2025
article
OpenAlex
Sara Franco Ortega, Sally R. James, Lesley Gilbert, Karen Hogg et autres
To understand why close wild plant relatives of crops, such as Solanum dulcamara, are resistant to Ralstonia solanacearum we need genome resources to perform comparative studies and identify key genes and pathways. We de-novo assembled and annotated the genome of a resistant/tolerant …
gb
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