Shimeng Chen

Design of strong anti-corrosion and high electrical conductivity protective bilayer coatings on bipolar plates in PEMWE cells by machine learning

Yuanjiang Lv, Qiaomei Luo, Guosong Gu, Shimeng Chen et autres

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A dynamic re-alignment laser collimation strategy for attitude measurement of ultra-long mechanical arm

Huimin Xing, Shimeng Chen, Yinhao Li, Zhiwen Song et autres

Assessment of gabapentin efficacy in patients with KCNQ2-developmental epileptic encephalopathy

Juan Xiong, Xia You, Huazhen Li, Chen Chen et autres

KCNQ2‑related developmental epileptic encephalopathy (KCNQ2‑DEE) is characterized by intractable epilepsy, cognitive impairment, and behavioral problems, highlighting the urgent need for precision therapies. This study aimed to promote the clinical application of gabapentin, a known Kv7 channel opener, in KCNQ2‑DEE by evaluating its …

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Impact of Oil Spill Stress on Amino Acid Abundance in Heterosigma akashiwo

Dan Xue, Haohan Su, Jie Yu, Xiaowen Yang et autres

Background: Oil spills have dramatically increased, causing significant damage and pollution to marine ecosystems. The entry of petroleum hydrocarbons into the ocean may lead to the occurrence of harmful algal blooms (HABs). The amino acid changes in harmful algae after oil spills …

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Fiber optic fluorescence sensor for copper ion detection

Z Zhang, Shimeng Chen, Yiwen Zhang

Conventional methods for detecting copper ions (Cu2+) are often limited by their dependence on complex instrumentation, prohibitive costs, and inability to support rapid on-site analysis. To overcome these challenges, this study establishes a novel fiber optic fluorescence sensing platform integrating hydrogel-encapsulated CdSe/ZnS …

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Evanescent field fiber biosensor based on SMF-FBG-MMF composite structure

Hang Yang, Shimeng Chen, Wanqi Huang, Jianzhong Li

To address the the issues of complex manufacturing processes and high costs associated with traditional fiber Bragg grating (FBG) evanescent field sensors, we propose an evanescent field FBG biosensor based on MXene nano-coating. This sensor combines an FBG with a multi-mode fiber, …

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A Near-Infrared Dual-Channel Polymer Optical Waveguide Sensor for Robotic Limb Motion Capture

Daifu Zheng, Jie Meng, Shimeng Chen, Zhenguo Jing et autres

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Enhanced electrocatalytic oxidation and highly sensitive, selective sensing of nitric oxide by Ce/Zr bimetallic UiO-67

Yao Shijun, Shimeng Chen, Shuhan Yang, Fei Ma

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The integration of plasma non-target metabolomics and lipidomics analysis for the discovery of global developmental delay/intellectual disability biomarkers

Baiyu Chen, Shimeng Chen, Juan Xiong, Miriam Kessi et autres

Background: This study aimed to identify metabolic signatures and potential biomarkers for global developmental delay (GDD) and intellectual disability (ID) using plasma metabolomics and lipidomics. The research sought to evaluate the feasibility of these methods for early identification and to explore the …

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Hydrophilic cladding fiber based on silicone hydrogel for temperature, humidity, and salinity detection

Lu Meng, Jie Meng, Daifu Zheng, Shimeng Chen et autres

We propose a hydrophilic cladding optical fiber based on silicone hydrogel (HCF-SH), employing a highly hydrophilic copolymeric silicone hydrogel as the cladding and 98% glycerol as the high-refractive-index core. Owing to its high water content and excellent biocompatibility, the silicone hydrogel responds …

Nanozyme Coating-Mediated Mitochondrial Metabolic Reprogramming of Macrophages for Immunomodulatory Osseointegration in Rheumatoid Arthritis Case

Shimeng Chen, Xiaoqi Liu, Wenhui Zhang, Bo Li et autres

Conventional titanium (Ti)-based implants often fail to achieve osseointegration in bone defects accompanied by rheumatoid arthritis (RA), primarily due to the RA pathological microenvironment, characterized by elevated reactive oxygen species (ROS) levels and hypoxia. This microenvironment induces mitochondria dysfunction and intracellular Ca …

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A Passive Elastic Fiber-Optic Sensor With Embedded Triboluminescent Materials for Portable Control Application

Chen‐Hao Wang, Weihan Li, Daifu Zheng, Shimeng Chen et autres

In recent years, elastic optical fibers have garnered significant attention for their emerging applications in biomedical engineering, intelligent sensing systems, photoelectric sensing and wearable robots. Concurrently, triboluminescent (TL) materials have exhibited notable capabilities in the domains of sensing indication and structural integrity …

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