Agatha Wisse

Trends in Mortality in People With HIV From 1999 through 2020: A Multicohort Collaboration

Erich S. Tusch, Lene Ryom, Annegret Pelchen–Matthews, Amanda Mocroft et autres

BACKGROUND: Mortality among people with human immunodeficiency virus (HIV) declined with the introduction of combination antiretroviral therapy. We investigated trends in mortality in people with HIV from 1999 through 2020. METHODS: Data were collected from the Data Collection on Adverse events of …

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Prescriptions for treatment in patients with PCD: does clinical routine match recommendations?

Eugènie Collaud, Agatha Wisse, Eva S.L. Pedersen, Barben Juerg et autres

There are no evidence-based treatment guidelines for Primary Ciliary Dyskinesia (PCD). Treatments vary between and within countries. Generally accepted management recommendations include immunization for pneumococcus and influenza, physical activity, nasal therapy, physiotherapy and antibiotic treatment in patients with infections. We aim to …

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The Swiss Primary Ciliary Dyskinesia registry: an update

Myrofora Goutaki, Florian Samuel Halbeisen, Agatha Wisse, Juerg Barben et autres

Background: Central data collection in national and international registries is essential to answer open questions on rare diseases such as Primary Ciliary Dyskinesia. For this reason, the Swiss Primary Ciliary Dyskinesia Registry (CH-PCD) was founded in 2013. Methods: The registry records PCD …

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Prevalence and Clinical Outcomes of Poor Immune Response Despite Virologically Suppressive Antiretroviral Therapy Among Children and Adolescents With Human Immunodeficiency Virus in Europe and Thailand: Cohort Study

Elizabeth Chappell, Andrew Riordan, Gonzague Jourdain, Antoni Soriano‐Arandes et autres

BACKGROUND: In human immunodeficiency virus (HIV)-positive adults, low CD4 cell counts despite fully suppressed HIV-1 RNA on antiretroviral therapy (ART) have been associated with increased risk of morbidity and mortality. We assessed the prevalence and outcomes of poor immune response (PIR) in …

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Proceedings of the 3rd BEAT-PCD Conference and 4th PCD Training School

Hannah J. Farley, Bruna Rubbo, Zuzanna Bukowy‐Bieryłło, Mahmoud R. Fassad et autres

Primary ciliary dyskinesia (PCD) is a chronic suppurative airways disease that is usually recessively inherited and has marked clinical phenotypic heterogeneity. Classic symptoms include neonatal respiratory distress, chronic rhinitis since early childhood, chronic otitis media, recurrent airway infections leading to bronchiectasis, chronic …

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Neonatal manifestations in Primary Ciliary Dyskinesia: a multinational cohort study

Myrofora Goutaki, Florian Samuel Halbeisen, Agatha Wisse, Israel Amirav et autres

Background: Neonatal respiratory distress (NRDS) and other neonatal manifestations are reported commonly in patients with Primary Ciliary Dyskinesia (PCD): Despite this, most patients remain undiagnosed until much later in life. We calculated the prevalence of neonatal manifestations in a large multinational dataset …

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Increasing preoperative body size in breast cancer patients between 2002 and 2016: implications for prognosis

Agatha Wisse, Helga Tryggvadottir, Maria Simonsson, Karolin Isaksson et autres

Overweight and obesity are increasing worldwide, but the extent in breast cancer patients is unknown. The two aims were to study secular trends in preoperative body mass index (BMI), waist circumference, and breast volume and their impacts on clinical outcome. BMI, waist …

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High Treatment Uptake in Human Immunodeficiency Virus/Hepatitis C Virus–Coinfected Patients After Unrestricted Access to Direct-Acting Antivirals in the Netherlands

Anne Boerekamps, Astrid M. Newsum, Colette Smit, Joop E. Arends et autres

Background: The Netherlands has provided unrestricted access to direct-acting antivirals (DAAs) since November 2015. We analyzed the nationwide hepatitis C virus (HCV) treatment uptake among patients coinfected with human immunodeficiency virus (HIV) and HCV. Methods: Data were obtained from the ATHENA HIV …

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Patienten over arbocuratieve samenwerking.

H.N. Plomp, Agatha Wisse, J.R. Anema