Kimberly L. Brady

Factors Influencing Stages of Mohs Micrographic Surgery: A Comprehensive Analysis

Elissa J. Goorman, Mehdi Boostani, Michael J. Bax, Cerrene N. Giordano et autres

BACKGROUND: Mohs micrographic surgery (MMS) achieves high cure rates for basal cell carcinoma (BCC) but may require multiple stages when tumors extend beyond clinically visible margins. Preoperative biopsy subtype information may help identify cases most likely to require additional stages and therefore …

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A call for standardization of photodynamic therapy clinical studies

Mehdi Boostani, Drew Kuraitis, Kimberly L. Brady, Marcelle Grassi et autres

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Mohs Margins in Stage‐1‐Positive Basal Cell Carcinoma Are Often Histologically Shallow Irrespective of Biopsy Subtype: A Retrospective Analysis Using Histologic Depth as a Surrogate for In Vivo Imaging Detectability

Mehdi Boostani, Elissa J. Goorman, Michael J. Bax, Kimberly L. Brady et autres

BACKGROUND: Presurgical biopsy subtype guides basal cell carcinoma (BCC) risk stratification, but how well it predicts histopathology at the Mohs margin is unclear. Noninvasive imaging with reflectance confocal microscopy (RCM), line-field confocal optical coherence tomography (LC-OCT), and optical coherence tomography (OCT) may …

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Advances in enhancing photodynamic therapy for actinic keratoses and field-damage with laser pretreatments: A scoping review

Mehdi Boostani, Cerrene N. Giordano, Drew Kuraitis, Kimberly L. Brady et autres

BACKGROUND: Actinic keratoses (AKs) arise in chronically ultraviolet-damaged skin and may progress to cutaneous squamous cell carcinoma. Photodynamic therapy (PDT) is an established field-directed treatment, but efficacy may be limited by lesion thickness, hyperkeratosis, inadequate photosensitizer penetration, acral location, and immunosuppression. Laser …

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Cost and cost-effectiveness of Mohs micrographic surgery versus conventional excision for nonmelanoma skin cancer: A scoping review

Mehdi Boostani, Kimberly L. Brady, Michael J. Bax, Kegon T.K. Tan et autres

Background: Nonmelanoma skin cancers (NMSCs) are commonly treated with conventional excision (CE) or Mohs micrographic surgery (MMS), but their relative cost-effectiveness remains uncertain. Objective: To summarize the available economic evidence comparing MMS and CE for NMSC and, secondarily, to identify methodological gaps …

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Novel imaging techniques for tumor margin detection in basal cell carcinoma: a systematic scoping review of FDA and EMA‐approved imaging modalities

Mehdi Boostani, Szabolcs Bozsányi, Mariano Suppa, Carmen Cantisani et autres

Mohs micrographic surgery (MMS) is the gold standard for removing basal cell carcinomas (BCCs) due to its ability to guarantee 100% margin evaluation through frozen section histopathology, offering the highest cure rate among current treatments. However, noninvasive imaging technologies have emerged as …

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Rare Skin Cancers

Kimberly L. Brady

Solid organ transplant recipients (SOTRs) have an increased risk of malignancy, with skin cancer being the most common. Although immunotherapy has revolutionized the oncologic landscape for the treatment of advanced malignancies, its use in the transplant population remains controversial because of the …

Cutaneous Squamous Cell Carcinoma Arising in a Split Thickness Skin Graft Donor Site in a Patient With Systemic Lupus Erythematosus

Molly R. Marous, Kimberly L. Brady

*Department of Dermatology, University of Rochester Medical Center, Rochester, New York †Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York The authors have indicated no significant interest with commercial supporters.

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Commentary on Assessment of Materials to Prevent Sutures Cutting Through Atrophic Skin

Kimberly L. Brady, Franki Lambert Smith

*Department of Dermatology, Roswell Park Comprehensive Cancer Center, Buffalo, New York †Department of Dermatology, University of Rochester Medical Center, Rochester, New York The authors have indicated no significant interest with commercial supporters.

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Ultraviolet imaging in dermatology

Jacob A. Mojeski, Mohammed A. Almashali, Peter Jowdy, Megan E. Fitzgerald et autres

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Sebaceous Carcinoma Treated With Mohs Micrographic Surgery

Kimberly L. Brady, Eva A. Hurst

BACKGROUND: Sebaceous carcinoma is a rare and potentially aggressive adnexal neoplasm with historic data indicating high rates of recurrence, metastasis, and cancer-specific mortality. OBJECTIVE: To evaluate the incidence of local recurrence, metastasis, disease-specific mortality, and all-cause mortality and to identify work-up approaches. …

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Cutaneous metastasis from penile squamous cell carcinoma resembling carcinoma en cuirasse

Kimberly L. Brady, Glynis Scott, Elaine S. Gilmore

Penile squamous cell carcinoma is a rare malignancy seen more frequently in developing nations. Metastasis occurs in a predictable manner, with superficial lymph node involvement occurring first, followed by deep lymph node involvement, and then distant spread. Brain, lung, liver, and bone …

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