Mehdi Boostani

Clinically relevant evidence on imaging and artificial intelligence in hidradenitis suppurativa

Ximena Wortsman, Mehdi Boostani, Norbert Kiss, Valentina Dini et autres

This review provides a comprehensive analysis of the role of imaging and artificial intelligence in hidradenitis suppurativa (HS), highlighting the strengths and limitations of each modality and providing the level of evidence for each imaging technique. To date, ultrasound has emerged as …

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Factors Influencing Stages of Mohs Micrographic Surgery: A Comprehensive Analysis

Elissa J. Goorman, Mehdi Boostani, Michael J. Bax, Cerrene N. Giordano et autres

BACKGROUND: Mohs micrographic surgery (MMS) achieves high cure rates for basal cell carcinoma (BCC) but may require multiple stages when tumors extend beyond clinically visible margins. Preoperative biopsy subtype information may help identify cases most likely to require additional stages and therefore …

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Dietary polypodium leucotomos supplementation minimally alters acute UV-induced edema and erythema and fails to protect against chronic UV-induced photocarcinogenesis in SKH1 mice

Mehdi Boostani, Drew Kuraitis, Ethan D. Herbold, Erin Tracy et autres

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Merkel cell carcinoma: A clinically oriented mini-review for dermatologists

Mehdi Boostani, Maya Androus, Avery Williams, Alicia Goldenberg et autres

BACKGROUND: Merkel cell carcinoma (MCC) is a rare but highly aggressive cutaneous neuroendocrine malignancy with mortality rates exceeding melanoma at comparable stages. Its incidence is increasing worldwide, particularly among elderly, immunosuppressed, and fairskinned individuals. Clinically, MCC often presents as a rapidly enlarging, …

Mohs Margins in Stage‐1‐Positive Basal Cell Carcinoma Are Often Histologically Shallow Irrespective of Biopsy Subtype: A Retrospective Analysis Using Histologic Depth as a Surrogate for In Vivo Imaging Detectability

Mehdi Boostani, Elissa J. Goorman, Michael J. Bax, Kimberly L. Brady et autres

BACKGROUND: Presurgical biopsy subtype guides basal cell carcinoma (BCC) risk stratification, but how well it predicts histopathology at the Mohs margin is unclear. Noninvasive imaging with reflectance confocal microscopy (RCM), line-field confocal optical coherence tomography (LC-OCT), and optical coherence tomography (OCT) may …

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Dermoscopy guided high-frequency ultrasound features of basal cell carcinoma subtypes compared with histopathology: a multicenter study

Mehdi Boostani, Florencia Vera Morandini, Ximena Wortsman, Cristian Navarrete-Dechent et autres

Abstract Accurate non-invasive differentiation of basal cell carcinoma (BCC) subtypes is crucial for guiding treatment; however, current imaging tools have limitations in accessibility, depth resolution, and interpretability. To describe sonographic features of distinct BCC subtypes using dermoscopy-guided high-frequency ultrasound (DG-HFUS), and assess …

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Advances in enhancing photodynamic therapy for actinic keratoses and field-damage with laser pretreatments: A scoping review

Mehdi Boostani, Cerrene N. Giordano, Drew Kuraitis, Kimberly L. Brady et autres

BACKGROUND: Actinic keratoses (AKs) arise in chronically ultraviolet-damaged skin and may progress to cutaneous squamous cell carcinoma. Photodynamic therapy (PDT) is an established field-directed treatment, but efficacy may be limited by lesion thickness, hyperkeratosis, inadequate photosensitizer penetration, acral location, and immunosuppression. Laser …

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Evaluating Large Language Models for Melanocytic Lesion Pathology Report Interpretation

Sasha Severin, Mehdi Boostani, Lana Salloum, Szabolcs Bozsányi et autres

The authors declare no conflicts of interest. The data that support the findings of this study are available on request from the corresponding author. The data are not publicly available due to privacy or ethical restrictions.

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Robust image quality evaluation in optical coherence tomography of skin using global, region-independent metrics

Elnaz Babaee, Mehdi Boostani, Mostafa Charmi, Kamran Avanaki

Optical coherence tomography (OCT) is a powerful imaging modality for visualizing tissue microstructures, but its utility is often limited by artifacts such as speckle, intensity decay, and blurring. While numerous image enhancement algorithms have been proposed to address these issues, the field …

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Acute UV response of early erythema and late edema in SKH1 mice

Szabolcs Bozsányi, Rhea Carmel Glen Rodrigues, Ruby Elorm Acquah, Erin C. Tracy et autres

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Dermoscopy-Guided High-Frequency Ultrasound Imaging of Subcentimeter Cutaneous and Subcutaneous Neurofibromas in Patients with Neurofibromatosis Type 1

Krisztina Kerekes, Mehdi Boostani, Zseraldin Metyovinyi, Norbert Kiss et autres

Background: Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder characterized by cutaneous and subcutaneous neurofibromas, which impact quality of life. Dermoscopy-guided high-frequency ultrasound (DG-HFUS) integrates dermoscopy with 33 MHz ultrasound, enabling precise lesion localization and reproducible measurements. Objective: To characterize neurofibromas …

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Dermoscopy-guided high-frequency ultrasound: Principles and applications in dermatology

Mehdi Boostani, Ximena Wortsman, Giovanni Pellacani, Krisztián Füzesi et autres

Conventional skin imaging modalities are often bulky, expensive, and impractical for routine dermatology practice. There is a need for a portable, multimodal imaging tool that integrates high-resolution surface and subsurface visualization at the point of care. The aim of this study was …

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