M. Angela O’Neal

The Dawn of Functional Neurologic Disorder

M. Angela O’Neal, Barbara A. Dworetzky

Introduction There has been a renaissance in the understanding of Functional Neurological Disorder (FND). This is reflected by the increasing interest of clinicians and scientists in this common and disabling disorder, reflected in part by the successful establishment of the International Functional …

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Proposed criteria of levels of evidence for co‐occurring epilepsy in people with functional/dissociative seizures

S. V. Iyer, Zachary Duarte, Gabriela Figueiredo Pucci, Tara Pirnia et autres

OBJECTIVE: This work was undertaken to describe the level of evidence for co-occurring epileptic seizures in patients with known functional/dissociative seizures (FDS) using stratification criteria analogous to the International League Against Epilepsy criteria for functional seizures. METHODS: 18 years) with "documented" or …

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Ringing in the Ears and Pain in the Head

M. Angela O’Neal, Janet Waters, Jonathan H. Waters

Abstract The case presented in this chapter illustrates the classic clinical features of a low-pressure headache. The pathophysiology results from the loss of cerebrospinal fluid (CSF). This causes sagging of the brain, stretching of the bridging veins, and venodilation. The clinical history …

A Woman With Cognitive Concerns

M. Angela O’Neal, Sara C. LaHue

Abstract This chapter reviews the incidence and sex-specific risks for women developing Alzheimer’s disease (AD). The incidence of AD doubles every 5 years beginning at age 60 years. Furthermore, AD is two or three times more common in women. Observational trials suggested …

A Young Woman With Epilepsy and PCOS

M. Angela O’Neal, Caroline Just, Ginette Moores, Esther Bui

Abstract This chapter discusses preconception counseling and pregnancy in epilepsy. Reproductive-aged women on antiseizure medications (ASMs) might experience challenges related to medication noncompliance, unknown drug–drug interactions, and reproduction. Therefore, it is important for clinicians to routinely review patients’ reproductive plans, contraceptive options, …

Acute Headache in Pregnancy

M. Angela O’Neal, Addie Peretz

Abstract The chapter illustrates the characteristics of pituitary apoplexy. This anatomy of the pituitary, which predisposes to the condition, is described. The most common clinical feature is headache. Visual disturbance related to optic chiasm or optic nerve involvement is also common. Pituitary …

A Young Woman With Epilepsy and Family Planning

M. Angela O’Neal, Caroline Just, Ginette Moores, Esther Bui

Abstract This chapter discusses preconception counseling and pregnancy in epilepsy. Reproductive-aged women on antiseizure medications (ASMs) might experience challenges related to medication noncompliance, unknown drug–drug interactions, and reproduction. Therefore, it is important for clinicians to routinely review patients’ reproductive plans, contraceptive options, …

Functional Neurological Disorder Presenting After Concussion: A Retrospective Case Series

Ginger Polich, Gaston Baslet, M. Angela O’Neal, Rishab Gupta et autres

OBJECTIVE: Although a majority of individuals recover from a concussion within weeks of the index injury, a substantial minority of patients report persistent postconcussion symptoms. Some of these symptoms may reflect a diagnosis of functional neurological disorder (FND). The authors evaluated the …

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How Sex Hormones Affect Migraine: An Interdisciplinary Preclinical Research Panel Review

Frederick A. Godley, John Meitzen, Hadas Nahman‐Averbuch, M. Angela O’Neal et autres

Sex hormones and migraine are closely interlinked. Women report higher levels of migraine symptoms during periods of sex hormone fluctuation, particularly during puberty, pregnancy, and perimenopause. Ovarian steroids, such as estrogen and progesterone, exert complex effects on the peripheral and central nervous …

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Women and the risk of Alzheimer's disease

M. Angela O’Neal

Purpose of the review: This review will elucidate reasons to explain why women may be at greater risk for Alzheimer's disease. Recent findings: Potential mechanisms to explain sex and gender differences in Alzheimer dementia include: differences in risk associated with the apolipoprotein …

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Functional neurological disorder, physical activity and exercise: What we know and what we can learn from comorbid disorders

K. Boylan, Barbara A. Dworetzky, Gaston Baslet, Ginger Polich et autres

Functional neurological disorder (FND) is a common neurologic disorder associated with many comorbid symptoms including fatigue, pain, headache, and orthostasis. These concurrent symptoms lead patients to accumulate multiple diagnoses comorbid with FND, including fibromyalgia, chronic fatigue syndrome, postural orthostatic tachycardia syndrome, persistent …

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Contributors

J. Baker, Elizabeth Benge, Aaron L. Berkowitz, Shamik Bhattacharyya et autres

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