Siegfried Höfinger

Errichtung und Entwicklung des Wiener Lehrstuhls für Liturgiewissenschaft und Sakramententheologie (1965-2002)

Siegfried Höfinger

Die vorliegende Arbeit untersucht die Voraussetzungen der Gründung sowie die Entwicklung des Lehrstuhls für Liturgiewissenschaft und Sakramententheologie an der Katholisch-Theologischen Fakultät der Universität Wien mit besonderem Schwerpunkt auf die Zeit von den 1960er- bis in die 1990er-Jahre. Ziel ist es, die inhaltliche, …

Identification of Novel TAT-I24-Related Peptides with Antiviral Activities

Hanna Harant, Siegfried Höfinger, Reingard Grabherr, Zsolt Ruzsics et autres

To identify novel peptides with potential antiviral activities, a database search was performed based on the primary sequence of the peptide I24 (CLAFYACFC), the effective part of the antiviral peptide TAT-I24 consisting of peptide I24 and the cell penetrating TAT-peptide (amino-acids 48-60; …

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The European master for HPC curriculum

Pascal Bouvry, Mats Brorsson, Ramón Canal, Aryan Eftekhari et autres

International audience

In Vitro Profiling of the Antiviral Peptide TAT-I24

Theodhora Ziu, Ezgi Sambur, Zsolt Ruzsics, Hartmut Hengel et autres

The synthetic peptide TAT-I24 (GRKKRRQRRRPPQCLAFYACFC) exerts antiviral activity against several double-stranded (ds) DNA viruses, including herpes simplex viruses, cytomegalovirus, some adenoviruses, vaccinia virus and SV40 polyomavirus. In the present study, in vitro profiling of this peptide was performed with the aim of …

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CASTIEL 2 D3.2 Report on Training, Twinning, Mentoring and Mobility Activities in the Second Year

Siegfried Höfinger, Mary Kate Chessey, Aline Melinette, Tobias Haas et autres

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CASTIEL 2 D3.2 Report on Training, Twinning, Mentoring and Mobility Activities in the Second Year

Siegfried Höfinger, Mary Kate Chessey, Aline Melinette, Tobias Haas et autres

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Insights into receptor structure and dynamics at the surface of living cells

Frederik Steiert, Peter G. Schultz, Siegfried Höfinger, T. Müller et autres

Evaluating protein structures in living cells remains a challenge. Here, we investigate Interleukin-4 receptor alpha (IL-4Rα) into which the non-canonical amino acid bicyclo[6.1.0]nonyne-lysine (BCNK) is incorporated by genetic code expansion. Bioorthogonal click labeling is performed with tetrazine-conjugated dyes. To quantify the reaction …

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CASTIEL 2 D3.1 Report on Training, Twinning, Mentoring and Mobility Activities in the First Year

Martina Blažková, Siegfried Höfinger, Aline Melinette

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CASTIEL 2 D3.1 Report on Training, Twinning, Mentoring and Mobility Activities in the First Year

Martina Blažková, Siegfried Höfinger, Aline Melinette

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The Peptide TAT-I24 with Antiviral Activity against DNA Viruses Binds Double-Stranded DNA with High Affinity

Hanna Harant, Siegfried Höfinger, Franz Kricek, Christine Ruf et autres

The peptide TAT-I24, composed of the 9-mer peptide I24 and the TAT (48-60) peptide, exerts broad-spectrum antiviral activity against several DNA viruses. The current model of the mode of action suggests a reduction of viral entry and also a possible interaction with …

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Impact of the green tea ingredient epigallocatechin gallate and a short pentapeptide (Ile-Ile-Ala-Glu-Lys) on the structural organization of mixed micelles and the related uptake of cholesterol

Francesco Giangreco, Siegfried Höfinger, Evangelos Bakalis, Francesco Zerbetto

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Fast Approximate Evaluation of Parallel Overhead from a Minimal Set of Measured Execution Times

Siegfried Höfinger, Thomas Ruh, Ernst Haunschmid

Porting scientific key algorithms to HPC architectures requires a thorough understanding of the subtle balance between gain in performance and introduced overhead. Here we continue the development of our recently proposed technique that uses plain execution times to predict the extent of …

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