Pooya Roozdar

Minimal Clinically Important Difference of the Sinonasal Outcome Test in Sinonasal Malignancy

Sabrina L. Maoz, Michelle Lee, Jakob L. Fischer, Garret M. Choby et autres

Background: Sinonasal malignancies (SNM) are rare cancers associated with poor prognosis and impaired quality of life (QOL). The 22-question Sino-Nasal Outcome Test (SNOT-22) has been used to assess QOL in patients with SNM. Objective: To determine the minimal clinically important difference (MCID) …

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Endoscopic transnasal sphenopalatine ganglion block for chronic craniofacial pain

David T. Liu, Pooya Roozdar, Erik Chan, Michael Yong et autres

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Proton Beam vs Intensity-Modulated Radiotherapy in Olfactory Neuroblastoma

Anthony Tang, Samuel Adida, Jack K. Donohue, Brennan Olson et autres

Importance: Adjuvant radiotherapy can improve locoregional control and survival in patients with olfactory neuroblastoma (ONB), particularly with advanced-stage and histologic-grade disease. Standard radiotherapy treatment is with intensity-modulated radiotherapy (IMRT). Proton beam radiotherapy (PBRT) provides theoretical advantages in greater sparing of dose to …

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A Unique Case of Pediatric Orbital Nodular Fasciitis with a Confirmed USP6 Fusion Mutation

Rachel Frauches, Pooya Roozdar, Jonathan H. Lin, Natalie Homer

Nodular fasciitis is a benign, pseudoneoplastic condition often misdiagnosed as sarcoma due to its rapid growth, high cellularity, and mitotic activity. Herein is reported a case of a 7-year-old patient with a painless, enlarging nodule in the left superolateral orbit. Ultrasound revealed …

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1005 Subclonal Mismatch Repair Protein Abnormalities in Endometrial Endometrioid Carcinoma: A Retrospective Study of the Association with POLE Mutation, Abnormal p53 Immunohistochemistry, MLH1 Promoter Methylation, and Lynch Syndrome

Anthony N. Karnezis, Pooya Roozdar, Jaclyn C. Watkins

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Durable reconstitution of sinonasal epithelium by transplant of CFTR gene corrected airway stem cells

Dawn T. Bravo, Sriram Vaidyanathan, Jeanette Baker, Vrishti Sinha et autres

Abstract Modulator agents that restore cystic fibrosis transmembrane conductance regulator (CFTR) function have revolutionized outcomes in cystic fibrosis, an incurable multisystem disease. Barriers exist to modulator use, making local CFTR gene and cell therapies attractive, especially in the respiratory tract. We used …

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Unilateral Versus Bilateral Endoscopic Resection of Olfactory Neuroblastoma: Pooled Analysis From Prospective and Retrospective Multicenter Data

Arash Abiri, Theodore V. Nguyen, Haidee Chen, Elise Krippaehne et autres

BACKGROUND: Olfactory neuroblastoma (ONB) is a rare sinonasal malignancy primarily treated with surgery. For tumors arising from the olfactory area, traditional treatment involves transcribriform resection of the anterior cranial fossa. Surgery can be performed with unilateral or bilateral resection depending on extent …

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Comparing Efficacy of Steroid Irrigation + Steroid‐Eluting Sinus Stent Versus Steroid Irrigation Alone for Maintaining Frontal Sinus Patency After Sinus Surgery: A Randomized Controlled Trial

M. Fieux, Julia E. Noel, Pooya Roozdar, Caio Athayde Neves et autres

BACKGROUND: Steroid rinses and steroid-eluting stents are both options for preventing postoperative stenosis after frontal sinus surgery. This study aimed to assess whether steroid-eluting stents offer added benefit over steroid rinses alone in postoperative healing and long-term frontal sinus patency. METHODS: A …

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Tranexamic acid does not significantly lower postoperative bleeding after endoscopic sinus and nasal surgery

Ashoke Khanwalkar, Erik Chan, Pooya Roozdar, Dayoung Kim et autres

BACKGROUND: Postoperative epistaxis is a known possibility following endoscopic sinonasal surgery. Tranexamic acid (TXA) has been shown to reduce intraoperative blood loss and improve the visual field. This study evaluated the clinical efficacy of TXA when given at end of surgery to …

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Effect of dupilumab on Eustachian tube dysfunction in patients with chronic rhinosinusitis with nasal polyposis

Michael T. Chang, Pooya Roozdar, Yi‐Tsen Lin, Jennifer Y. Lee et autres

Peter H. Hwang: Speaker Bureau for Sanofi, Speakers Bureau and clinical trial funding for GlaxoSmithKline. All other authors declare no conflicts of interest.

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Applications of vibrational energy in the treatment of sinonasal disease: A scoping review

Katie M. Phillips, Pooya Roozdar, Peter H. Hwang

BACKGROUND: Acoustic energy and vibration therapy are emerging as helpful adjuncts among many disease states. There has been interest in how this technology can either serve as an alternative treatment or enhance delivery of medications to treat pathology within the nasal cavity …

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Venous thromboembolism rates and risk factors following endoscopic skull base surgery

Michael T. Chang, Kawinyarat Jitaroon, Sunhee Song, Pooya Roozdar et autres

BACKGROUND: Venous thromboembolism (VTE) is a potentially fatal perioperative complication. The objective of this study was to assess the rate and risk factors for VTE in endoscopic skull base surgery (ESBS). METHODS: This was a retrospective review of adults undergoing ESBS at …

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