Hui Huang

A clinical nomogram for evaluating occult central lymph node metastasis in clinically low-risk, unifocal papillary thyroid microcarcinoma

Li’nan Qin, Yunhe Liu, Xiwei Zhang, Song Ni et autres

Background This study aimed to develop and validate a clinical nomogram to predict the risk of central lymph node metastasis (CLNM) in patients with clinically low-risk papillary thyroid microcarcinoma (PTMC). Methods Patients with clinically low-risk PTMC were enrolled in this retrospective cohort …

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Transcriptomics Identify KCNJ2 as a Potential Novel Biomarker for the Postoperative Recurrence in Chronic Sinusitis

Minglang Zhou, Hui Huang, Chunbo Feng, Miao He et autres

Chronic rhinosinusitis (CRS) is a prevalent inflammatory disease of the upper respiratory tract with a relatively high postoperative recurrence rate. Transcriptomic profiling may facilitate the identification of biomarkers associated with disease recurrence. This study aimed to characterize the transcriptomic features of postoperative …

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Genomic landscape and phylogenetic insights of Burkholderia pseudomallei over two decades in southern China and its global surveillance

Hua Wu, Zichen Lei, Shaowen Chen, Xuming Wang et autres

Melioidosis, caused by Burkholderia pseudomallei, is an endemic infectious disease with high mortality in tropical and subtropical regions. Large-scale epidemiological data remain insufficient in China, while comprehensive data integrating genomic epidemiology are rare worldwide. Herein, performed a retrospective analysis of 554 culture-confirmed …

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Exploring the Complexities of TGF-β Signaling in Keloids: Beyond the Classical Smad Pathway

Jiao Mo, Hui Huang, Baochen Zhu, Ruiheng Liao et autres

Keloid is a benign skin disease with excessive growth of fibroblasts, characterized by too much abnormal extracellular matrix deposited in the dermis. It is generally believed that transforming growth factor-β (TGF-β) is the core cytokine that causes keloid. Previously, it was thought …

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Expert Consensus on the Clinical Application of Bronchoscopy in Secondary pneumonitis After Solid Tumor Treatment

Xi Chen, Jing Zheng, Jingjing Qu, Cuihong Cai et autres

Patients with solid tumors who have undergone anti-tumor therapy are at high risk of developing pneumonia. The etiologies include both infectious and non-infectious factors (e.g., immune-related pneumonia, drug-induced pulmonary toxicity, and radiation pneumonitis). Given that etiological diagnosis can be challenging in some …

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Outcomes after direct thrombectomy versus combined thrombolysis and thrombectomy in acute large artery occlusion stroke with atrial fibrillation

Hao Shu, Hui Huang, Xiaona Xu, Ruqian He

Background The role of intravenous thrombolysis (IVT) before endovascular thrombectomy (EVT) remains controversial, particularly for patients with acute large vessel occlusion (LVO) due to atrial fibrillation (AF), who may have a poor response to thrombolysis. Furthermore, robust evidence is lacking regarding the …

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Association between dietary intake of fatty acids, central obesity, and OAB: insights from a prospective cohort for weight management and dietary prevention

Bo Chen, Jianmin Wu, Yi-Xiang Wang, Jie Chen et autres

Background: Overactive bladder (OAB) is a common condition that affects both men and women, but its relationship with central obesity and the dietary intake has not been adequately elucidated. Objectives: Our study aims to investigate associations between central obesity replacement indices, dietary …

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The Prevalence and Death Risk Factors of Nonthyroidal Illness Syndrome in Patients During Hospitalization With Diabetic Foot Ulcers

Hongping Gong, Zhen-yi Li, Panpan Zha, Raju Bista et autres

Background Thyroid hormone abnormalities are common in critical illness and are associated with poor prognosis. The purpose of this study is to investigate the prevalence of nonthyroidal illness syndrome (NTIS) and evaluate its clinical outcomes in hospitalized patients with diabetic foot ulcers …

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D-Dimer Variability Predicts Venous Thromboembolism in Postoperative Fracture Patients: A Single-Center Retrospective Cohort Study

Xin-Miao Chen, Hui Huang, Fen-Hua Jin, Hui Li et autres

BackgroundVenous thromboembolism (VTE) is a potentially life-threatening complication following traumatic fractures. Although plasma D-dimer is widely used as a biomarker of coagulation and fibrinolysis, its utility as a standalone predictor of postoperative VTE remains limited due to poor specificity. This study aimed …

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Dynamic interplay of atherogenic index and body roundness in cardio-renal-metabolic disease: a multi-state analysis

Chenxi Jin, Le-Rong Liu, Qi Zhong, Xiaoyan Wang et autres

Type 2 diabetes mellitus (T2DM), atherosclerotic cardiovascular disease (CVD) and chronic kidney disease (CKD) are closely linked at epidemiological, pathophysiological, and molecular levels, forming cardio-renal-metabolic (CRM) disease. Their multimorbidity leads to multi-organ dysfunction and increased cardiovascular risk, making prevention and management crucial …

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Machine Learning Design of Soft Magnetoresponsive Materials With Multidirectional Fields

Xin Ye, Yilong Zhang, Hanlin Zhu, Hui Huang et autres

ABSTRACT Soft magnetoresponsive materials (SMRMs) with programmable magnetization profiles can exhibit a wide range of motion postures under dynamically controllable magnetic fields. Although the complex magnetization distribution provides a vast design space, the intricate nonlinear deformation and magneto‐mechanical coupling mechanisms make the …

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Radiation-induced glioblastoma stem cell-mediated T cell exhaustion via EGR1-Gal3-LAG3 axis in glioblastoma

Hui Huang, Chenhua Li, Hao You, Zhen Zhang et autres

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