Ruqian He

Outcomes after direct thrombectomy versus combined thrombolysis and thrombectomy in acute large artery occlusion stroke with atrial fibrillation

Hao Shu, Hui Huang, Xiaona Xu, Ruqian He

Background The role of intravenous thrombolysis (IVT) before endovascular thrombectomy (EVT) remains controversial, particularly for patients with acute large vessel occlusion (LVO) due to atrial fibrillation (AF), who may have a poor response to thrombolysis. Furthermore, robust evidence is lacking regarding the …

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Nomogram Model for Predicting the Functional Outcomes in Patients With Minor Ischemic Stroke Based on Clinical Characteristics and Small Vessel Disease Burden

Ruqian He, Xiaona Xu, Xiachan Chen, Haoye Cai et autres

OBJECTIVES: Our purpose is to assess the role of total small vessel disease (SVD) burden affecting the clinical outcome and develop and validate a prognostic nomogram for minor ischemic stroke (MIS) patients. METHODS: Between January 2018 and April 2023, 454 MIS patients …

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Association of CSF soluble TREM1 levels with hippocampal atrophy in cognitively impaired older adults

Hao Shu, Xiaona Xu, Xuerong Huang, Ruqian He

Background: Recent studies have shown that cerebrospinal fluid (CSF) levels of soluble triggering receptor expressed on myeloid cells 1 (sTREM1) are elevated in individuals with Alzheimer's disease (AD), though the relationship between CSF sTREM1 and hippocampal atrophy remains to be elucidated. The …

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A bibliometric analysis of cerebral small vessel disease

Xiaoxiao Yan, Yongyin Zhang, Ruqian He, Xiachan Chen

Background Cerebral small vessel disease (CSVD) is a significant contributor to both stroke and dementia. While numerous studies on CSVD have been published, herein, we have conducted a bibliometric examination of the literature on CSVD, revealing its hot spots and emerging patterns. …

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The effect of Clot Burden Score on clinical outcomes in acute ischemic stroke patients with atrial fibrillation treated with endovascular thrombectomy

Ruqian He, Yongyin Zhang, Xuerong Huang, Hao Shu

Background The Clot Burden Score (CBS) is used to assess thrombus length. The influence of CBS on functional outcome was barely analyzed in patients with acute ischemic stroke (AIS) with atrial fibrillation (AF). Purpose To assess the association between CBS and clinical …

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Efficacy, Influencing Factors, and Safety of Alteplase Intravenous Thrombolysis in Patients with Acute Ischemic Stroke Combined with Atrial Fibrillation

Yongyin Zhang, Haoye Cai, Hao Shu, Ruqian He et autres

Ischemic stroke is the most common type of stroke. Intravenous thrombolytic therapy with alteplase is currently the most effective method to improve the prognosis of patients with acute cerebral infarction. The purpose of this study was to investigate the efficacy and safety …

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External validation and comparison of two prediction models for seizure recurrence after the withdrawal of antiepileptic drugs in adult patients

Jiahe Lin, Siqi Ding, Xueying Li, Yingjie Hua et autres

OBJECTIVE: The models currently available for predicting the risk of seizure recurrence after antiepileptic drug (AED) withdrawal in adult epilepsy patients include the prediction model developed by Lamberink et al (Lamberink model, 2017) and the Medical Research Council prediction model (MRC model, …

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Relative Seizure Relapse Risks Associated with Antiepileptic Drug Withdrawal After Different Seizure-Free Periods in Adults with Focal Epilepsy: A Prospective, Controlled Follow-Up Study

Xinshi Wang, Ruqian He, Rongyuan Zheng, Siqi Ding et autres

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Substitution has better efficacy than add-on therapy for patients with focal epilepsy after their first antiepileptic drug treatments fail

Xiao Wang, Ruqian He, Qingyi Zeng, Yi Wang et autres

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Investigation of microstructural abnormalities in white and gray matter around hippocampus with diffusion tensor imaging (DTI) in temporal lobe epilepsy (TLE)

Yixin Bao, Ruqian He, Qingyi Zeng, Pan Zhu et autres

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Risk of seizure relapse after antiepileptic drug withdrawal in adult patients with focal epilepsy

Ruqian He, Qingyi Zeng, Pan Zhu, Yixin Bao et autres

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Comparative Long-Term Effectiveness of a Monotherapy with Five Antiepileptic Drugs for Focal Epilepsy in Adult Patients: A Prospective Cohort Study

Qingyi Zeng, Tiantian Fan, Pan Zhu, Ruqian He et autres

OBJECTIVE: To evaluate and compare long-term effectiveness of five antiepileptic drugs (AEDs) for monotherapy of adult patients with focal epilepsy in routine clinical practice. METHODS: Adult patients with focal epilepsy, who were prescribed with carbamazepine (CBZ), valproate (VPA), lamotrigine (LTG), topiramate (TPM), …

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