Accès ouvert
2025
article
OpenAlex
Surajit Dey, Wenying Lu, Prabuddha S. Pathinayake, Maddison Waters et autres
Introduction: Asthma and chronic obstructive pulmonary disease (COPD) overlap (ACO) is a term used to describe a patient with coexisting clinical features of asthma and COPD. We have previously reported that epithelial to mesenchymal transition (EMT) is active in the lungs of …
au
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Accès ouvert
2025
article
OpenAlex
Heinrich Christoph Weber, G Bassett, Sukhwinder Singh Sohal, Sarah Jane Prior
Introduction The prevalence of childhood food allergies is escalating, with Australia notably affected. Research primarily originates from urban centres, leaving rural areas underrepresented. This study examines food allergy prevalence among 1,052 grade 1 and 2 children in regional and rural Tasmania. Method …
au
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Accès ouvert
2024
article
OpenAlex
Sarah Jane Prior, G Bassett, Claire Griffiths, Smriti Sinha et autres
BACKGROUND/OBJECTIVES: The COVID-19 pandemic created many challenges for health services, particularly during lockdown periods. Asthma is one of the most common childhood conditions, and children with asthma are generally cared for in an outpatient setting. In regional Northwest Tasmania, during the COVID-19 …
au
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Accès ouvert
2024
article
OpenAlex
Surajit Dey, Wenying Lu, Heinrich Christoph Weber, Collin Chia et autres
Asthma COPD overlap (ACO) is a clinical term that describes patients with persistent airflow limitation, and clinical/physiologic characteristics consistent with both asthma and chronic obstructive pulmonary disease (COPD) [1]. The hallmark pathological features of asthma and COPD are airway inflammation and remodelling. …
au
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Accès ouvert
2023
article
OpenAlex
Surajit Dey, Wenying Lu, Greg Haug, Collin Chia et autres
BACKGROUND: Although asthma and chronic obstructive pulmonary disease (COPD) are two distinct chronic airway inflammatory diseases, they often co-exist in a patient and the condition is referred to as asthma-COPD overlap (ACO). Lack of evidence regarding the inflammatory cells in ACO airways …
au
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2023
conference-abstract
OpenAlex
Wenying Lu, Surajit Dey, Archana Vijay Gaikwad, Prem Bhattarai et autres
Background: Lack of evidence on the inflammatory cell populations in ACO airways has led to their poor prognosis and treatment. Aim: To enumerate inflammatory cell changes in the airway wall of ACO and compare them with asthma (AS), COPD current smokers (CS) …
au, gb
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Accès ouvert
2022
article
OpenAlex
Surajit Dey, Wenying Lu, Heinrich Christoph Weber, Sally Young et autres
Management of patients with asthma COPD overlap (ACO) is clinically challenging due to insufficient evidence of pathological changes in these patients. In this cross-sectional study, we evaluated airway remodeling in endobronchial biopsies from a total of 90 subjects, which included 12 ACO, …
au
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Accès ouvert
2022
article
OpenAlex
Heinrich Christoph Weber, G Bassett, Laura K Hollingsworth, Vincent WS Gan et autres
AIM: Explore the prevalence of childhood anaphylaxis and clinical presentation of anaphylaxis in children across two regional emergency departments over a 7-year period. METHODS: Retrospective audit of all children (0-18 years) presenting to emergency from 1 January 2010 to 31 December 2016 …
au
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Accès ouvert
2022
article
OpenAlex
Sheryl van Nunen, Melanie Burk, Pamela K. Burton, Geoffrey Ford et autres
Background: Temperate grass (eg, ryegrass) pollen is a major driver of seasonal allergic rhinitis (SAR) and asthma risks, including thunderstorm asthma. Data for the effectiveness of temperate grass pollen allergen immunotherapy (AIT) in SAR patients from the southern hemisphere, who are frequently …
au
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Accès ouvert
2021
article
OpenAlex
Sharon P. Luccisano, Heinrich Christoph Weber, Giuliana O. Murfet, Iain Kilpatrick Robertson et autres
Maternal obesity in pregnancy, a growing health problem in Australia, adversely affects both mothers and their offspring. Gestational diabetes mellitus (GDM) is similarly associated with adverse pregnancy and neonatal complications. A low-risk digital medical record audit of antenatal and postnatal data of …
au
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2021
conference-abstract
OpenAlex
Surajit Dey, Wenying Lu, James Markos, Josie Larby et autres
Background: Management of ACO is clinically challenging due to insufficient evidence on pathological changes in these patients. Aim: To evaluate large airway remodelling changes in patients with ACO compared to asthma, COPD ex-smokers (ES) and current smokers (CS), non-smoking normal controls (NC), …
au
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2021
conference-abstract
OpenAlex
Samuel James Brake, Wenying Lu, James Markos, Josie Larby et autres
Aim: To perform detailed tissue analysis of SARS-CoV-2 adhesion sites in surgically resected small airway tissue. Methods: This study included 16 patients with COPD, of which 8 were current smokers with COPD (COPD-CS) and 8 ex-smokers with COPD (COPD-ES), 7 normal lung …
au, ca
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