Gerry Polton

Osteosarcoma of the appendicular skeleton in dogs: consensus and guidelines

Gerry Polton, Juan Borrego, Francisco Clemente-Vicario, Craig A. Clifford et autres

Osteosarcoma (OSA) in dogs poses a clinical challenge to veterinary practitioners across the globe. As knowledge evolves, so too do clinical practices. However, there remain uncertainties and controversies. There is value for the veterinary community at large in the generation of a …

gb, mx, pl, de, jp, pt, br, se, hu, us (code pays fourni par la source)

Lymph-node transcriptomics define prognostic immune states in mucosal melanoma and reveal IBA1 as a practical biomarker for improved prognosis

Laura Blackwood, Kevin Donnelly, Yuting Lu, Alison Meynert et autres

Abstract Mucosal melanoma (MM) is a rare and aggressive cancer in humans with poor prognosis and limited response to immunotherapy or targeted therapy. Progress has been hindered by the lack of immune-competent, translational models. Dogs develop oral mucosal melanoma (OMM), a biologically …

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Oronasal mucosal melanoma is defined by two transcriptional subtypes in humans and dogs with implications for diagnosis and therapy

Kelly Blacklock, Kevin S. Donnelly, Yuting Lu, Jorge del Pozo et autres

Mucosal melanoma is a rare melanoma subtype associated with a poor prognosis and limited existing therapeutic interventions, in part due to a lack of actionable targets and translational animal models for preclinical trials. Comprehensive data on this tumour type are scarce, and …

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Companion interview

Gerry Polton

Oronasal mucosal melanoma is defined by two transcriptional subtypes in humans and dogs with implications for diagnosis and therapy

Kelly Blacklock, Kevin S. Donnelly, Yuting Lu, Jorge del Pozo et autres

Abstract Mucosal melanoma is a rare melanoma subtype associated with a poor prognosis and limited existing therapeutic interventions, in part due to a lack of actionable targets and translational animal models for pre-clinical trials. Comprehensive data on this tumour type is scarce, …

gb, us, gr, ca (code pays fourni par la source)

Diagnosis and surgical management of an extraskeletal osteosarcoma of the brachial plexus in a Belgian shepherd dog

Zoe R. Nalborczyk, Elizabeth J. Hall, Rodolfo Cappello, Gerry Polton et autres

An 11-year-old Belgian shepherd presented with progressive right thoracic limb lameness. Computed tomography and magnetic resonance imaging revealed a brachial plexus neoplasm and cytology was suggestive of a sarcoma. The patient underwent forequarter amputation and hemilaminectomy of the fifth cervical to first …

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Corrigendum: Melanoma of the dog and cat: consensus and guidelines

Gerry Polton, Juan Borrego, Francisco Clemente-Vicario, Craig A. Clifford et autres

[This corrects the article DOI: 10.3389/fvets.2024.1359426.].

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Outcome and Prognostic Factors for Canine Stage 2 Anal Sac Gland Carcinoma

Sofia Ramos, Michael Macfarlane, Carla Rohrer Bley, Laura Marconato et autres

Clinical abstract presented at BSAVA Congress 2024. See full text for abstract and see clinical abstract sessions for a recording of the presentation. Abstracts are presented as supplied and have not been edited.

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Melanoma of the dog and cat: consensus and guidelines

Gerry Polton, Juan Borrego, Francisco Clemente-Vicario, Craig A. Clifford et autres

Melanoma of the dog and cat poses a clinical challenge to veterinary practitioners across the globe. As knowledge evolves, so too do clinical practices. However, there remain uncertainties and controversies. There is value for the veterinary community at large in the generation …

gb, pl, de, jp, pt, se, hu, us (code pays fourni par la source)

In vivo exposure of the bladder using a non-invasive high intensity focused ultrasound toroidal transducer

Victor Delattre, Sophie Cambronero, Yao Chen, Gail ter Haar et autres

A toroidal high-intensity focused ultrasound (HIFU) transducer was used to expose normal bladder wall tissues non-invasively in vivo in a porcine model in order to investigate the potential to treat bladder tumors. The transducer was divided into 32 concentric rings with equal …

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The Prognostic Role of Preoperative Hematological and Inflammatory Indices in Canine Appendicular Osteosarcoma

Konstantinos Rigas, Jean‐Benoit Tanis, Emanuela Morello, Gerry Polton et autres

Hematological indices play a prognostic role in human osteosarcoma (OSA), but data are limited in dogs. The aim of this retrospective multicentric cohort study was to investigate the prognostic significance of pre-operative hematological/inflammatory indices in a cohort of client-owned dogs with appendicular …

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Patterns of nodal metastases, biological behaviour and prognosis of canine mast cell tumours of the pinna: A multi‐institutional retrospective study

Carmit Chalfon, Silvia Sabattini, Irina Gramer, Joanna S. Morris et autres

Canine cutaneous mast cell tumours (cMCTs) of the pinna have been associated with an aggressive biological behaviour, although data remain scarce. The knowledge acquired over the past years on histologic gradings, and the value of lymph node (LN) staging, may help in …

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