2025
conference-abstract
OpenAlex
Ola Sayed Ahmed, Heba Morsy, Heba Ateya, Abdel‐Rahman N. Zekri
Abstract Background Genetic profiling of the tumor microenvironment involves looking at a lot of genes to figure out what roles they play in the progression of cancer and in how well treatments work. The tumor microenvironment is responsible for tumor genesis, metastasis, …
Égypte
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Accès ouvert
2025
article
OpenAlex
Aya Ahmed, Abeer Mahmoud Badr, Emad M. Elzayat, Marwa Mohanad et autres
Abstract Background Rapid pulmonary replication of SARS-CoV-2 can potentially trigger a strong immune response. In people with coronavirus disease 2019 (COVID-19) symptoms, cytokine storm syndrome often leads to acute respiratory distress syndrome and respiratory failure, which are key causes of mortality. Viral …
Égypte
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Asmaa E. Ahmed, Hassan Abol‐Enein, Adel A. El‐Morsi, Ahmed S. El‐Hefnawy et autres
Hepatitis C virus (HCV) is the most common infection worldwide. The correlation between HCV and renal cell carcinoma (RCC) is still mysterious. Therefore, the relationship between HCV and RCC was investigated. The study included 100 patients with RCC; 32 with HCV infection, …
Égypte
(code pays fourni par la source)
2024
conference-abstract
OpenAlex
Amira Salah El-Din Youssef, Mohamed Ibrahim Ragab, Heba Ateya, Mostafa Hamed Elberry et autres
Abstract Background: The mismatch repair (MMR) deficiency is a potential predictive biomarker for immunotherapy efficacy, particularly in colorectal cancer (CRC), where alterations in various DNA polymerases and MMR genes are prevalent. The accumulation of these genetic aberrations may cause a subsequent neoantigen …
Égypte
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Mona S. Abdellateif, Abdel‐Rahman N. Zekri
Hepatocellular carcinoma (HCC) is a major health problem worldwide, especially for patients who are suffering from end-stage liver disease (ESLD). The ESLD is considered a great challenge for clinicians due to the limited chance for liver transplantation, which is the only curative …
Égypte
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Amira Salah El-Din Youssef, Abdel‐Rahman N. Zekri, Marwa Mohanad, Samah Aly Loutfy et autres
This study aimed to identify BRCA1/2 mutational patterns in the tissue and blood of Egyptian colorectal cancer (CRC) patients and to study the possible correlation of this mutational pattern with Human papillomavirus (HPV) infection. Eighty-two colonoscopic biopsies and forty-six blood samples were …
Égypte
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Accès ouvert
2023
article
OpenAlex
Doaa M. Badr, Mariam Ahmed Fouad, Marwa Mahmoud Hussein, Salem Salem et autres
Treatment with 5-fluorouracil (5-FU) based therapy is still used for colorectal cancer (CRC). Epigenetics has become a focus of study in cancer because of its reversibility besides its known regulatory functions. In this study, we will monitor the change in microRNAs (miRNAs) …
Égypte, us
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Abdel‐Rahman N. Zekri, Abeer Ahmed Bahnassy, Magda Mourad, Ibrahim Malash et autres
Abstract Background Breast cancer stem cells (BCSCs) have a crucial role in breast carcinogenesis, development, and progression. The aim of the current study is to characterize the BCSCs through the genetic profiling of different BCSCs phenotypic subsets to determine their related genetic …
Égypte
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Auhood Abdel-Monem Nassar, Abdel‐Rahman N. Zekri, Mahmoud Mohamed Kamel, Mostafa Hamed Elberry et autres
Background: Precision oncology has been increasingly used in clinical practice and rapidly evolving in the oncology field. Thus, this study was performed to assess the frequency of germline mutations in early and late onset familial breast cancer (BC) Egyptian patients using multi-gene …
Égypte
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Riham M. Karkeet, Abdel‐Rahman N. Zekri, Mohamed M. Sayed‐Ahmed, Ghada M. Sherif et autres
AIM: The role of surgical castration and rosuvastatin treatment on lipid profile and lipid metabolism related markers was evaluated for their prognostic significance in metastatic prostate cancer (mPC) patients. METHODS: A total of 84 newly diagnosed castrated mPC patients treated with castration …
Égypte, us
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Auhood Abdel-Monem Nassar, Abdel‐Rahman N. Zekri, Mostafa Hamed Elberry, Ahmed M. Lymona et autres
This study aimed to investigate the impact of somatic mutations on various interleukin signaling pathways associated with grade II invasive breast cancer (BC) in Egyptian patients to broaden our understanding of their role in promoting carcinogenesis. Fifty-five grade II invasive BC patients …
Égypte
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Basma El-Helkan, Manal Asem Emam, Marwa Mohanad, Shadia A. Fathy et autres
Breast cancer (BC), the most common type of malignant tumor, is the leading cause of death, having the highest incidence rate among women. The lack of early diagnostic tools is one of the clinical obstacles for BC treatment. The current study was …
Égypte
(code pays fourni par la source)