Qing Yu Huang

Low‐Concentration Enhancement Effect: Enabling Sensitive Detection of EML4 ‐ ALK Variants via Multiplex RT ‐ MIRA

Xiaodong Ren, Luo Xi-yao, Jin-Mi Li, Xian-Ge Sun et autres

OBJECTIVE: ALK fusion variant detection is essential for guiding targeted therapy in non-small cell lung cancer (NSCLC). The emerging reverse transcription multi-enzyme isothermal rapid amplification (RT-MIRA) technology exhibits substantial potential in molecular diagnostics, enabling efficient variant profiling. However, its performance and optimization …

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A photoregulated DNA nanoflower for spatiotemporally controlled monitoring of adenosine triphosphate in living cells

Liu Wang, Xiaodong Ren, Ning Su, Qian Mi et autres

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Suppressing Blood-Cell Migration Lag via Dean-Cycle Phase Regulation Enables High-Purity CTC Enrichment in an Inertial Microfluidic Array

Taihang Wu, Haozheng Li, XiangE Sun, Xiaodong Ren et autres

Circulating tumor cells (CTCs) are valuable liquid-biopsy biomarkers, yet their extreme rarity makes high-purity, high-throughput enrichment challenging. In spiral inertial microfluidics, high cell loading induces long-range hydrodynamic interactions that broaden the focused blood-cell stream; consequently, a subpopulation completes the ~0.5 and ~1.0 …

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Lactobacillus murinus Alleviates High Fructose‐Induced MASLD by Boosting Arginine Production

Xinglin Mo, Guilin Zhao, Lanlan Liu, Lan Zhen et autres

ABSTRACT Over the past few years, the prevalence of high‐fructose diets has become a significant inducer of metabolic dysfunction‐associated steatotic liver disease (MASLD). The effects and pathological mechanisms of high dietary fructose on gut microbiota and its subsequent role in MASLD remain …

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A case report of hemophagocytic lymphohistiocytosis secondary to tislelizumab and bevacizumab combination therapy for renal cell carcinoma

Linli Shi, Xiaobing Li, Rong Xie, Xianmin Zhu et autres

Background: Recently, the widespread application of immune checkpoint inhibitors (ICIs) in the field of tumor therapy has brought clinical benefits to many patients with advanced disease. Simultaneously, immune-related adverse events (irAEs) have attracted growing attention from the academic community. ICI-related hemophagocytic lymphohistiocytosis …

cn, jp (code pays fourni par la source)

The Role and Research Progress of CD8+ T Cells in Sepsis

Xianwen Wang, Qing Yu Huang, Zhihong Zuo, Zhanwen Wang et autres

Sepsis is a systemic inflammatory response syndrome induced by infection, characterized by high morbidity and mortality, and responsible for over 11 million deaths worldwide annually. Recent studies have demonstrated that immune dysfunction represents a core element in the pathophysiology of sepsis, in …

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Urine-derived stem cells efficiently assemble into micro-bone organoids supported by decellularized bone matrix microparticles for rapidly repairing bone defects through direct filling and paracrine functions

Yi‐Ting Chen, Liang Zhang, Zeyu Li, Xinrun Wang et autres

The repair of large bone defects remains a significant challenge in orthopedic clinical practice. This study aims to rapidly cultivate a novel type of bone organoids (BOs), namely uBOs (USCs@DBM-MPs derived BOs), by utilizing self-developed highly biomimetic decellularized bone matrix microparticles (DBM-MPs) …

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Joint Detection Based on Virtual Angular Domain Channels for Massive Grant-Free Access Systems

Shanshan Zhang, Peng Zhang, Jianhui Mao, Qing Yu Huang et autres

To meet the access demands of massive communication, this paper studies a grant-free massive multiple-input multiple-output (MIMO) system. By transforming channels into the virtual angular domain, we study a one-phase scheme to identify active devices, estimate channels, and detect signals jointly. The …

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Interference Mitigation in 4.9 GHz ISAC Networks: A Multi-domain Resource Management Approach

Junyu Dong, Peng Zhang, Songtao Gao, Qing Yu Huang et autres

Integrated Sensing and Communication (ISAC) is a key enabler for sixth-generation (6G) networks and the low-altitude economy (LAE). However, its deployment faces significant challenges due to limited resources in multi-base station (BS) scenarios. Existing approaches struggle with scalability in multi-BS networks and …

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Machine Learning-Assisted Terahertz Metagrating Biosensor for Label-Free Bacterial Identification Based on Spectral Fingerprinting

Wenjing Yu, Yupeng Long, Junjie Luo, Daohong Zhou et autres

Rapid and accurate identification of pathogenic bacteria is pivotal for enabling early clinical diagnosis and precision antimicrobial therapy. In this study, we developed a label-free bacterial detection platform that integrates terahertz (THz) metagrating with machine learning algorithms to identify specific pathogens through …

cn, Nigéria, fr, pk, us (code pays fourni par la source)

Electrospun Nanofibers Loaded with Concentrated Growth Factors and Nanohydroxyapatite for the Healing of Alveolar Bone in Tooth Extraction Wounds

Qing Yu Huang, Linzi Han, Qunli Guan, Hang Wang et autres

Abstract The healing of tooth extraction wounds is significantly influenced by various factors, including interference from the oral microenvironment, invasion of gingival tissue, and inflammation of the alveolar socket, all of which contribute to the substantial loss of bone tissue in the …

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Synthesis and Tribological Properties of Polyoxometalate-Based Miktoarm Star Copolymers

Hua Xue, Qing Yu Huang, Sheng‐Chao Qiu, Fengchun Liang et autres

Both organomolybdenum complexes and nanoparticles have been widely used as high-performance lubricant additives for friction and wear reduction. Polyoxometalates (POMs) are intermediate between them and similarly show excellent lubricating properties. In this work, a series of polyoxometalate-based poly(stearyl methacrylate) (PSMA n )–poly(ethylene …

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