Rawya Charif

Tuberculosis incidence in solid organ transplant recipients in Europe: A multicenter TBnet cohort study

Berit Lange, Thomas Theo Brehm, Sandra M. Arend, Miguel Arias-Guillén et autres

BACKGROUND: Solid organ transplant (SOT) recipients face elevated tuberculosis risk, yet optimal prevention strategies in low- to medium-incidence regions remain unclear. METHODS: We conducted a multicenter retrospective cohort study of adult SOT recipients transplanted between 2007 and 2012 at 15 European centers, …

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Outcomes of living donor kidney transplantation from extended criteria donors to extended criteria recipients: A retrospective cohort study

Nikolaos-Andreas Anastasopoulos, Rawya Charif, Marina Loucaidou, Paul Herbert et autres

BACKGROUND Living donor kidney transplantation (LDKT) is considered the gold standard for treating end-stage kidney disease. Previous studies have highlighted the impact of donor and recipient demographics in influencing post-transplant outcomes. We believe that patient and graft outcomes in a tertiary university …

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Non-crystalline light chain proximal tubulopathy, a morphologically protean entity

Andreas Kousios, Sarah Blakey, Linda Moran, Maria Atta et autres

BACKGROUND: Light chain proximal tubulopathy (LCPT) is a rare form of paraprotein-related disease, occurring in two main histopathological forms: crystalline and non-crystalline. The clinicopathological features, treatment strategies and outcomes, especially of the non-crystalline form, are not well described. METHODS: We conducted a …

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P156 London based pilot study screening new starters of dialysis for latent tuberculosis infection (LTBI)

James Korolewicz, Kavina Manalan, Neill Duncan, Mira A. Coleman et autres

Background Latent TB infection (LTBI) remains an important reservoir of TB even in low incidence countries. The prevalence of latent infection is higher in patients with chronic kidney disease and those receiving dialysis.1 Those with LTBI on renal replacement therapy (RRT) are …

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Outcome and effect of vaccination in SARS-CoV-2 Omicron infection in hemodialysis patients: a cohort study

Damien Ashby, Ben Caplin, Richard Corbett, Elham Asgari et autres

BACKGROUND: Hemodialysis patients are at high risk of Covid-19, though vaccination has significant efficacy in preventing and reducing the severity of infection. Little information is available on disease severity and vaccine efficacy since the dissemination of the Omicron variant. METHODS: In a …

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Diagnosis of tuberculosis in dialysis and kidney transplant patients

Mahrukh Ayesha Ali, Dhriti Dosani, Richard Corbett, Lina Johansson et autres

BACKGROUND AND OBJECTIVES: In patients with chronic kidney disease the risk of developing Tuberculosis is increased, while the presentation is often atypical making the diagnosis more difficult. The aim of this study is to describe the presentation of Tuberculosis in dialysis and …

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Management of the Acute Transplant

Hannah Maple, Rawya Charif, Jack Galliford, Adam McLean et autres

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Longevity of SARS-CoV-2 immune responses in hemodialysis patients and protection against reinfection

Candice Clarke, Maria Prendecki, Amrita Dhutia, Jaslyn Gan et autres

Patients with end stage kidney disease receiving in-center hemodialysis (ICHD) have had high rates of SARS-CoV-2 infection. Following infection, patients receiving ICHD frequently develop circulating antibodies to SARS-CoV-2, even with asymptomatic infection. Here, we investigated the durability and functionality of the immune …

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Longevity of SARS-CoV-2 immune responses in haemodialysis patients and protection against reinfection

Candice Clarke, Maria Prendecki, Amrita Dhutia, Claire Edwards et autres

ABSTRACT Background Patients with end stage kidney disease (ESKD) receiving in-centre haemodialysis (ICHD) have had high rates of SARS-CoV-2 infection. Following infection, ICHD patients frequently develop serological evidence of infection, even with asymptomatic disease. The aim of this study is to investigate …

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P156 A London centre based review of tuberculosis post kidney transplantation

Kavina Manalan, M Park, Chathura B. Ratnayake, Rawya Charif et autres

The incidence of active tuberculosis (TB) post renal transplantation is much higher than the general population. This has previously been described as presenting in the first year following solid organ transplantation and is predominantly due to reactivation of latent TB infection (LTBI)(1). …

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Informing the Risk of Kidney Transplantation Versus Remaining on the Waitlist in the Coronavirus Disease 2019 Era

Candice Clarke, Gaetano Lucisano, Maria Prendecki, Sarah Gleeson et autres

Introduction There are limited data pertaining to comparative outcomes of remaining on dialysis versus kidney transplantation as the threat of coronavirus disease 2019 (COVID-19) remains. In this study we delineate the differential risks involved using serologic methods to help define exposure rates. …

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Demographic Variability of Kidney Function in Live Donors: A Single-Centre Analysis

Tina Thomson, Andreas Kousios, Rawya Charif, Honeylet Orr et autres

Background: Live donation is encouraged as better outcomes in kidney transplant recipients. Donor assessment requires thorough evaluation but kidney function varies with demographics. We compre mGFR with the performance of eGFR formulas and creatinine clearances Methods: Analysis of 997 live donors between …

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