Ruji Wu

PARP Inhibitor Plus Androgen-receptor Signaling Inhibitor Versus the Same Inhibitor Alone in Homologous-Recombination-Repair-Altered Metastatic Prostate Cancer Across the Hormone-Sensitive and Castration-Resistant Continuum: A Systematic Review and Meta-Analysis

Yanfeng Su, Ruji Wu, Huien Pan, Haofeng Yuan

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A study on the relationship between the weight-adjusted waist index and kidney stone prevalence mediated by diabetes: data from NHANES 2007–2018

Yanfeng Su, Ruji Wu, Jiawei He, H. Y. Pan

This study investigated the association between the weight-adjusted waist circumference index (WWI) and the prevalence of kidney stones among U.S. adults with diabetes, addressing the knowledge gap regarding the role of central obesity in kidney stone formation. Using data from the National …

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Non-epithelial Circulating Tumor Cells Enhance Disease Progression in High-risk Prostate Cancer through EMT and COL1A1 Expression

Yiyuan Li, Ruji Wu, Hua Wang, Meinong Zhong et autres

Introduction: Circulating tumor cells (CTCs) are important prognostic indicators for malignancies.However, a reliable positive/negative cutoff value of non-epithelial (NE + : hybrid and mesenchymal) CTCs phenotype in prostate cancer (PCa) patients has not been established.Here, we aimed to determine the cutoff value …

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Verification of cell cycle-associated cyclin-dependent kinases facilitated prostate cancer progression by integrated bioinformatic analysis and experimental validation

Yean Huang, Shuo Lu, Yi Chen, Yunhao Qing et autres

Introduction: Cell cycle-associated cyclin-dependent kinases (ccCDKs) are essential regulators known to control cell division and facilitate tumorigenesis and progression. However, there is currently no comprehensive study of distinct ccCDKs in prostate cancer (PCa). The purpose of this study was to determine the …

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The role of programmed death-ligand 1 and non-epithelial circulating tumor cells in locally advanced prostate cancer.

Ke Li, Yunhua Mao, Yiyuan Li, Ruji Wu et autres

e17557 Background: Circulating tumor cells (CTCs) is considered as an effective prognostic biomarker in malignancies. It is recently recognized that detections of programmed death-ligand 1 (PD-L1) and mesenchymal markers in CTCs may improve the predictive value. Therefore, we aimed to determine the …

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MP09-15 PROGRAMMED DEATH-LIGAND 1 POSITIVE AND NON-EPITHELIAL SUBTYPE IN CIRCULATING TUMOR CELLS PREDICT LOCALLY ADVANCED PROSTATE CANCER PROGRESSION AND GUIDE THE IMMUNOTHERAPY AFTER SURGERY

Ke Li, Yiyuan Li, Ruji Wu, Yunhua Mao et autres

INTRODUCTION AND OBJECTIVE: Circulating tumor cells (CTCs) is considered as “liquid biopsy” for tumor prognosis, and the detection of programmed death-ligand 1 (PD-L1) expressing in CTCs could promote the predictive efficiency. However, there are not standard of cut-offs to discriminate PD-L1 positive/negative …