H. Y. Pan

Depressive symptoms and ADL limitation improve risk stratification for incident cardiovascular disease in older adults with diabetes: a multicohort prediction-model development and independent external validation study

H. Y. Pan

This registration documents the protocol, exposures, outcomes, and statistical analysis plan for a multicohort study of whether depressive symptoms, cognitive impairment, and limitation in activities of daily living (ADL) add incremental value to 5-year risk stratification for incident cardiovascular disease (CVD) among …

Heterogeneous cardiovascular benefit of guideline-concordant risk-factor control according to multimodal health-reserve trajectories across HRS, ELSA, SHARE and CHARLS

H. Y. Pan

Title: Heterogeneous cardiovascular benefit of guideline-concordant risk-factor control according to multimodal health-reserve trajectories across HRS, ELSA, SHARE and CHARLS Study type: Observational prospective cohort study Brief abstract: This pre-registered multi-cohort study aims to test whether longitudinal multimodal health-reserve trajectories (physical function, cognition, …

Anode‐Free Lithium Batteries Enabled by Solid Polymer Electrolytes

Yuezheng Liu, Jingfu Shi, Yifan Wang, Shengnan He et autres

Anode-free solid polymer electrolytes (AF-SPEs) offer a compelling route to maximize cell-level energy density while improving safety, cost, and manufacturability by replacing the anode with a bare current collector and leveraging ultrathin, low-density polymer membranes. This review explores key design strategies for …

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Bifidobacterium animalis ssp. lactis 420 and Cordyceps militaris Synergistically Modulate the Gut Microbiota by Increasing Mucin 2 Production

Ziyang Deng, Yi Wang, Jike Shuai, Miaomiao Chen et autres

Background: Probiotics and medicine food homology are known to offer gentle approaches to prevent obesity, although it is difficult with such approaches to satisfy consumers’ requirements to lose weight quickly. The probiotic strain Bifidobacterium animalis ssp. lactis 420 (B420) and Cordyceps militaris …

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Laparoscopic Delivery of a MnO 2 ‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Jie Lin, H. Y. Pan, Ke Wu, Junjie Nan et autres

ABSTRACT Recurrence and metastasis are the primary causes of mortality in hepatocellular carcinoma (HCC), primarily driven by an immunosuppressive tumor microenvironment. This study developed a multifunctional flexible patch (MnO 2 ‐P‐ICG NFs) based on electrospun SiO 2 gel fibers whose surface is …

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Entropy Engineering-Driven Solid Solution of Metal Carbide Nanoparticles for Electrocatalytic Hydrogen Evolution Reaction

D. Liu, Haiwei Yang, Yujie Fang, Peng Chen et autres

The incorporation of immiscible elements into a solid-solution ultrafine nanoparticle provides extensive possibilities in pursuing extraordinary properties, yet remains a significant challenge, especially in conductive compounds with strong chemical bonds. Herein, we propose a strategy of high-entropy engineering and lattice distortion to …

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Manganese Phosphide Enables Oxygen Modulation in Co‐Free Li‐Rich Mn‐Based Oxides cathode for Reversible Anionic Redox

Qi Wu, Xin Zhang, Sihong Zhu, Ruizi Wang et autres

ABSTRACT Cobalt‐free lithium‐rich manganese‐based oxides (LRMOs), which have high capacity and cost‐effectiveness, are promising cathode materials for the next generation high energy density lithium‐ion batteries. Nevertheless, their practical application remains hindered by capacity fading, voltage degradation and constrained rate capability. In the …

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Surface Assembling of Individual Probiotics with pH-Responsive Epigallocatechin Gallate Nanoparticles against DSS-induced colitis

Suqing Lan, Jike Shuai, Ziyang Deng, Yunxuan Li et autres

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Differential Effects of Commercial Food-Grade Carrageenan Preparations on DSS-Induced Colitis and Gut Microbiota in Mice

Jiyu Nie, Danying Chen, Chengfeng Yu, Zengliang Jiang et autres

Carrageenan (CGN) is widely used in processed foods and is typically supplied as a commercial preparation blended with other hydrocolloids to improve gelling properties, rather than as a single purified polymer. However, safety evaluations and mechanistic studies have largely focused on CGN …

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Ni–Fe Dual‐Site Polymer Catalyst for High Performance and Stable Electrochemical Urea Synthesis from CO 2 and NO 3 −

Daming Feng, Zhenghao Lyu, Q. J. Zhang, Hui Li et autres

The electrochemical synthesis of urea from nitrate (NO 3 − ) and carbon dioxide (CO 2 ) presents a sustainable alternative to conventional methods, mitigating pollution and reducing energy consumption. Herein, a rationally designed Ni–Fe bimetallic pyromellitic acid polymer catalyst (Ni‐PMDA@Fe) is …

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Dynamic Regulation of Interfacial Hydrogen‐Bond Networks for Enhanced Electrocatalytic Performance

Zi‐Tian Lei, Wen‐Gang Cui, Yang Zhang, Ke Wang et autres

ABSTRACT Electrocatalysis is central to sustainable energy conversion and industrial electrosynthesis, yet its efficiency and selectivity are profoundly governed by the dynamic interfacial microenvironment, particularly the hydrogen‐bond networks (HBNs) formed among catalysts, electrolytes, and intermediates. Unlike isolated hydrogen bonds, interfacial HBNs exhibit …

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Ginsenoside Rg1 promotes skin flap survival by alleviating mitochondrial oxidative stress and apoptosis via the JNK/ERK/p38 pathway

H. Y. Pan, Ping Xu, Kaitao Wang, Jialong Yang et autres

Background: Meyer, has demonstrated protective effects against ischemia in various tissues. This study endeavors to explore whether Rg1 mitigates mitochondrial oxidative stress and apoptosis to enhance flap survival, and investigates the underlying mechanisms. Materials and methods: Male rats' McFarlane flap models were …

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