Christy Chang

Sequencing in over 50,000 cases identifies coding and structural variation underlying atrial fibrillation risk

Seung Hoan Choi, Sean J. Jurgens, Ling Xiao, Matthew C. Hill et autres

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Topologically Controlled Syntheses of Unimolecular Oligo[n]catenanes

Nathan D. Colley, Mark A. Nosiglia, Sheila L. Tran, Gray H. Harlan et autres

High Resolution Image Download MS PowerPoint Slide Catenanes are a well-known class of mechanically interlocked molecules that possess chain-like architectures and have been investigated for decades as molecular machines and switches. However, the synthesis of higher-order catenanes with multiple, linearly interlocked molecular …

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Variant-specific inflation factors for assessing population stratification at the phenotypic variance level

Tamar Sofer, Xiuwen Zheng, Cecelia Laurie, Stephanie M. Gogarten et autres

In modern Whole Genome Sequencing (WGS) epidemiological studies, participant-level data from multiple studies are often pooled and results are obtained from a single analysis. We consider the impact of differential phenotype variances by study, which we term 'variance stratification'. Unaccounted for, variance …

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One-Pot Synthesis of a Linear [4]Catenate Using Orthogonal Metal Templation and Ring-Closing Metathesis

Nathan D. Colley, Mark A. Nosiglia, Lei Li, Faheem Amir et autres

The efficient synthesis of well-defined, linear oligocatenanes possessing multiple mechanical bonds remains a formidable challenge in the field of mechanically interlocked molecules. Here, a one-pot synthetic strategy is described to prepare a linear [4]catenate using orthogonal metal templation between a macrocycle precursor, …

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Publisher Correction: Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries

Seyedeh M. Zekavat, Sanni Ruotsalainen, Robert E. Handsaker, Maris Alver et autres

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

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Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke

Matthew Traylor, Cathy R. Zhang, Poneh Adib‐Samii, William J. Devan et autres

OBJECTIVE: For 3,670 stroke patients from the United Kingdom, United States, Australia, Belgium, and Italy, we performed a genome-wide meta-analysis of white matter hyperintensity volumes (WMHV) on data imputed to the 1000 Genomes reference dataset to provide insights into disease mechanisms. METHODS: …

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The Transmission of Electrons through Thin Metallic Foils

Christy Chang, C. Sharp Cook, H. Primakoff

Experimental studies have been made on the relative transmission of positrons and negatrons in the energy range 50-750 kev through aluminum and platinum windows of an end-window-type G-M counter. In qualitative agreement with the theoretical predictions that more scattering takes place in …

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