Vasileios Exadaktylos

Artificial intelligence (AI)-powered imaging for objective psoriasis severity assessment at home: Feasibility and reliability in a randomized clinical trial

Mariona Oliver, Monika Molnárová, Menthe Bergmans, Rahul Ranjan et autres

Background: Psoriasis requires long-term monitoring, yet conventional tools like the Psoriasis Area and Severity Index (PASI) are time-consuming and prone to inter-rater variability. Artificial intelligence (AI) may overcome these limitations by providing remote and objective assessments. Objectives: To evaluate the feasibility and …

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The effect of physical activity timing on insomnia and sleep quality: a randomized cross-over trial in older adults

Gali Albalak, Raymond Noordam, Marjan van der Elst, Thomas Drop et autres

Abstract Background Insomnia symptoms are common in older adults. While observational studies suggest physical activity (PA) timing affects health outcomes, its effect on sleep remains unclear. We compared morning versus evening PA effects on insomnia severity and sleep quality in older adults …

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Multi‐omics profiling of chronic immune‐mediated skin diseases: SKINERGY protocol and strategic evaluation

N. G. Koster, J. M. P. A. van den Reek, E. M. G. J. de Jong, Sylvia van Beugen et autres

BACKGROUND: The Dutch flagship project Next Generation ImmunoDermatology (NGID) aims to profile five chronic immune-mediated inflammatory skin diseases: atopic dermatitis (AD), plaque psoriasis (PSO), hidradenitis suppurativa (HS), chronic spontaneous urticaria (CSU) and cutaneous lupus erythematosus (CLE) in comparison with cutaneous T-cell lymphoma …

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Digital solutions, real-world challenges: lessons from mHealth trials in oncology

Dominique G. Stuijt, Igor Radanović, Vasileios Exadaktylos, Ellen Kapiteijn et autres

The use of mobile health (mHealth) technologies in oncology, such as wearable devices and smartphone applications, is gaining momentum due to their potential to improve quality of life, enhance treatment adherence, and positively impact survival outcomes for cancer patients. However, as a …

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Remote monitoring in chronic immune-mediated inflammatory diseases: A systematic review of active and passive approaches

Mariona Oliver, Jannik Rousel, Jan W. Schoones, Hanna Niehues et autres

Contains fulltext : 331734.pdf (Publisher’s version ) (Open Access)

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Added value of a wrist-worn device for assessing tremor in Parkinson’s disease: reliability and validity of tremor evaluation at home

Dagmar H. Hepp, Kenneth Ocran, Antónia Szántó, J.J. van Hilten et autres

Clinical assessment and self-report of tremor in Parkinson's disease (PD) have several limitations, including recall bias and lack of sensitivity. Wearable-based technology offers an opportunity to address these shortcomings. We investigated the test-retest reliability of wearable tremor assessment and compared the different …

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197 Smart Imaging and Deep Learning for Objective Psoriasis Lesion Scoring: A Scarletred AI Proof-of-Concept Study

Monika Molnárová, Jannik Rousel, M. Bergmans, Tessa Niemeyer‐van der Kolk et autres

188P Digital remote monitoring and patient-reported quality of life in a phase II trial combining melphalan percutaneous hepatic perfusion with ipilimumab and nivolumab in metastatic uveal melanoma (CHOPIN): Insights from mHealth endpoints

Dominique G. Stuijt, I. Radanovic, Leendert J. Hoek, Vasileios Exadaktylos et autres

Uveal melanoma (UM) is the most common intraocular malignancy in adults. Despite effective local treatment, up to half of patients develop hepatic metastases, which are associated with poor prognosis. The CHOPIN trial (NCT04283890) was conducted to evaluate the safety and efficacy of …

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Disturbed rest-activity rhythm in Parkinson's disease: Associations with motor severity and orthostatic hypotension

Manon D. Mijnsbergen, Vasileios Exadaktylos, Jacobus J. van Hilten, Dagmar H. Hepp et autres

BackgroundThe rest-activity rhythm (RAR) captures the distribution of rest and activity periods between and within days. Disturbed RAR has been observed in Parkinson's disease (PD), but the contribution of motor and non-motor symptoms to RAR disturbances remains unclear.ObjectiveTo evaluate the extent to …

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Disturbed rest-activity rhythm in Parkinson’s disease: associations with motor severity and orthostatic hypotension

Manon D. Mijnsbergen, Vasileios Exadaktylos, Jacobus J. van Hilten, Dagmar H. Hepp et autres

nl (code pays fourni par la source)

Medication Effects on Bradykinesia, Tremor, Gait and Balance in Parkinson's Disease, Measured by Wearable Sensors

R. H. A. Weijer, Antónia Szántó, Vasileios Exadaktylos, B.K. Soek et autres

nl, us, be (code pays fourni par la source)

Physical recovery after local resection of nonpedunculated rectal adenomas and T1 carcinomas: endoscopic submucosal dissection versus transanal minimally invasive surgery

Nik Dekkers, Matthijs D. Kruizinga, Hao Dang, Frederik E. Stuurman et autres

BACKGROUND AND AIMS: Rehabilitation of physical activity is an important functional outcome after endoscopic surgery. Our aim was to quantitatively assess recovery after endoscopic submucosal dissection (ESD) and transanal minimally invasive surgery (TAMIS). METHODS: In the TRIASSIC study (Netherlands Trial Registry: NL7083), …

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