Antónia Szántó

27 Clinical trials: improving design and execution

Antónia Szántó

hu (code pays fourni par la source)

Long-term outcomes and prognosis of mixed cryoglobulinemia: a European multicenter study of 1,294 patients

David Saadoun, P Cacoub, Soledad Retamozo, Marco Sebastiani et autres

OBJECTIVES: To assess the long-term outcomes and prognostic factors of patients presenting with all-cause mixed cryoglobulinaemia vasculitis (CryoVas). METHODS: A European multicentre cohort study (EuroCryo) of 1294 patients presenting with all-cause CryoVas. RESULTS: The main aetiology for CryoVas was Hepatitis C Virus …

fr, es, it, si, ro, hu, pl, us, br (code pays fourni par la source)

Immunological signatures in patients with Sjögren's disease: association with systemic disease activity at diagnosis

Lucı́a Delgado, Alejandra Flores-Chávez, Antónia Szántó, Roberta Priori et autres

OBJECTIVES: This study aimed to analyse the relationship between distinct autoantibody combinations (immunological signatures) and systemic disease activity in patients with Sjögren's disease (SjD). The hypothesis was that specific multi-autoantibody signatures would be associated with higher systemic disease activity at diagnosis, serving …

es, gb, ca, hu, it, nl, tr, si, jp, mx, pt, pl, au, br, se, uy (code pays fourni par la source)

Sex disparities in the phenotype at diagnosis of Sjögren's disease: artificial intelligence-driven characterisation in 17,416 patients

Pilar Brito‐Zerón, Alejandra Flores-Chávez, Ildikó Fanny Horváth, Roberta Priori et autres

OBJECTIVES: Sjögren disease (SjD) predominantly affects females, but the early disease presentation in male patients remains poorly characterised due to historically small sample sizes. The aim of this study was to investigate sex‑based differences in the clinical phenotype at diagnosis of SjD …

gb, es, ca, hu, it, nl, tr, si, jp, mx, pt, pl, au, br, se, uy (code pays fourni par la source)

Added value of a wrist-worn device for assessing tremor in Parkinson’s disease: reliability and validity of tremor evaluation at home

Dagmar H. Hepp, Kenneth Ocran, Antónia Szántó, J.J. van Hilten et autres

Clinical assessment and self-report of tremor in Parkinson's disease (PD) have several limitations, including recall bias and lack of sensitivity. Wearable-based technology offers an opportunity to address these shortcomings. We investigated the test-retest reliability of wearable tremor assessment and compared the different …

nl, us (code pays fourni par la source)

Unveiling psychobiological correlates in primary Sjögren’s syndrome: a machine learning approach to determinants of disease burden

László Módis, András Matuz, Zsófia Aradi, Ildikó Fanny Horváth et autres

Introduction: Besides primary Sjögren's syndrome (pSS) is generally assessed through biological markers, growing evidence suggests that psychological and social factors-such as anxiety, depression, personality traits, and social support-may also play a role in disease burden. Relative contribution of these biopsychosocial dimensions to …

hu (code pays fourni par la source)

ABS0885 COMPLEMENT CONSUMPTION PATTERNS AS AN EARLY PREDICTOR OF SYSTEMIC SJÖGREN DISEASE: GENERATIVE ARTIFICIAL INTELLIGENCE-ASSISTED ANALYSIS USING STRATIFIED CROSS-VALIDATION GENERALIZABILITY MODELS

Pilar Brito‐Zerón, Alejandra Flores-Chávez, Lucila García, Ildikó Fanny Horváth et autres

Background: Complement consumption, characterized by decreased C3 and/or C4 levels, is a hallmark of immune complex-mediated inflammation and vascular involvement in patients with systemic autoimmune diseases. In patients with Sjögren Disease (SjD), hypocomplementemia at diagnosis has been mainly linked to an increased …

es, gb, it, nl, tr, si, mx, pt, au, jp, br, se, uy, hu (code pays fourni par la source)

POS0825 SEX DISPARITIES IN THE PHENOTYPE AT DIAGNOSIS OF SJÖGREN DISEASE: A GENERATIVE AI-DRIVEN CHARACTERIZATION IN 17,416 PATIENTS

Alejandra Flores-Chávez, Lucila García, Antónia Szántó, Roberta Priori et autres

Background: Although Sjögren disease (SjD) predominantly affects females, the characterization of early disease presentation in males remains understudied, hindering a comprehensive understanding of how sex may influence initial disease expression. Under-recognition of sex disparities in the disease presentation at diagnosis continues to …

es, gb, hu, it, nl, tr, si, mx, au, jp, br, se, uy, pt (code pays fourni par la source)

POS0827 AUTOANTIBODY-COMBINED SIGNATURES DELINEATING IMMUNOLOGIC CLUSTERS RELATED TO HIGH SYSTEMIC ACTIVITY IN PATIENTS WITH SJÖGREN DISEASE

Lucila García, Alejandra Flores-Chávez, Antónia Szántó, R. Priori et autres

Background: Patients with Sjögren disease (SjD) often present with multiple serum autoantibodies, most commonly ANA, RF, anti-Ro, and anti-La antibodies. Traditional approaches often examine a potential predictive role of these autoantibodies in isolation. However, the predictive power of specific combinations of autoantibodies …

gb, es, hu, it, nl, tr, si, mx, pt, au, jp, br, se, uy (code pays fourni par la source)

Additive Value of Rheumatoid Factor Isotypes in Sjögren’s Syndrome Patients with Joint Complaints of Different Etiologies—Can Rheumatoid Factor IgA Serve as an Early, Poor Prognostic Biomarker Candidate?

Zsófia Aradi, Bernadett Bói, Gábor Nagy, Péter Antal‐Szalmás et autres

The aim of the paper was to characterize rheumatoid factor IgA, IgG, and IgM isotypes in patients with Sjögren’s syndrome (SS) subsets, based on the absence or presence of joint complaints of different etiologies. In total, 164 SS patients were grouped based …

hu (code pays fourni par la source)

Medication Effects on Bradykinesia, Tremor, Gait and Balance in Parkinson's Disease, Measured by Wearable Sensors

R. H. A. Weijer, Antónia Szántó, Vasileios Exadaktylos, B.K. Soek et autres

nl, us, be (code pays fourni par la source)

Obesity: Friend or Foe in Sjögren’s Syndrome Patients?

Klára Mezei, L Nagy, Viktória Orosz, Zsófia Aradi et autres

BACKGROUND/OBJECTIVES: In Sjögren's syndrome, exocrine glands are destructed in an autoimmune-mediated process. Obesity is known to influence a wide range of diseases. This study aimed to examine whether obesity has an impact on the disease course of our patients with Sjögren's syndrome. …

hu (code pays fourni par la source)