Vicky Watts

Antibiotic chemoprophylaxis for close contacts of invasive group A streptococcus in community settings: Evidence review

Vicky Watts, Martine Usdin, Rachel Mearkle, Shiranee Sriskandan et autres

OBJECTIVES: Revised UK guidelines for the management of contacts of invasive group A Streptococcus (iGAS) infection in community settings were published in December 2022. We present the findings of a narrative review which informed the public health recommendations around the provision of …

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Genomic epidemiology and longitudinal sampling of ward wastewater environments and patients reveals complexity of the transmission dynamics of bla KPC-carbapenemase-producing Enterobacterales in a hospital setting

Nicole E Stoesser, Ryan George, Zoie Aiken, Hang T. T. Phan et autres

Abstract Background Healthcare-associated wastewater and asymptomatic patient reservoirs colonized by carbapenemase-producing Enterobacterales (CPE) contribute to nosocomial CPE dissemination, but the characteristics and dynamics of this remain unclear. Methods We systematically sampled wastewater sites (n = 4488 samples; 349 sites) and patients (n …

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Prescription Drug Misuse and Women

Bridgette J. Peteet, Vicky Watts, Emily C. Tucker, Monica Hanna et autres

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Prescription Drug Misuse and Women

Bridgette J. Peteet, Vicky Watts, Emily C. Tucker, Monica Hanna et autres

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Two Epidemics and a Pandemic: The Collision of Prescription Drug Misuse and Racism during COVID-19

P. Brown, Vicky Watts, Monica Hanna, Mariam Rizk et autres

The present study investigated the relationship between perceived racial discrimination and prescription drug misuse (PDM) among Asian, Black, and Latinx Americans during the COVID-19 crisis. U.S. racial/ethnic minorities may have been uniquely affected by two national and one global pandemic: the opioid …

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Invasive group A streptococcal infections in North West England: epidemiology, risk factors and fatal infection

Sarah Blagden, Vicky Watts, Neville Q. Verlander, Matthew Pegorie

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Genomic Epidemiology of Complex, Multispecies, Plasmid-Borne bla KPC Carbapenemase in Enterobacterales in the United Kingdom from 2009 to 2014

Nicole E Stoesser, Hang T. T. Phan, Anna C. Seale, Stephanie Thomas et autres

Carbapenem resistance in Enterobacterales is a public health threat. Klebsiella pneumoniae carbapenemase (encoded by alleles of the bla KPC family) is one of the most common transmissible carbapenem resistance mechanisms worldwide. The dissemination of bla KPC historically has been associated with distinct …

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Routine laboratory surveillance of antimicrobial resistance in community-acquired urinary tract infections adequately informs prescribing policy in England

Vicky Watts, Benjamin C. Brown, Maria Zahid Ahmed, André Charlett et autres

Abstract Objectives To assess whether resistance estimates obtained from sentinel surveillance for antimicrobial resistance (AMR) in community-acquired urinary tract infections (UTIs) differ from routinely collected laboratory community UTI data. Methods All patients aged ≥18 years presenting to four sentinel general practices with …

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Challenges of investigating a large food-borne norovirus outbreak across all branches of a restaurant group in the United Kingdom, October 2016

Mari Morgan, Vicky Watts, David James Allen, Daniele Curtis et autres

During October and November 2016, over 1,000 customers and staff reported gastroenteritis after eating at all 23 branches of a restaurant group in the United Kingdom. The outbreak coincided with a new menu launch and norovirus was identified as the causative agent. …

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Increased Risk for Invasive Group AStreptococcusDisease for Household Contacts of Scarlet Fever Cases, England, 2011–2016

Vicky Watts, Sooria Balasegaram, Colin Stewart Brown, Suzanna Mathew et autres

The incidence of scarlet fever in England and Wales is at its highest in 50 years. We estimated secondary household risk for invasive group A Streptococcus (iGAS) disease within 60 days after onset of scarlet fever. Reports of scarlet fever in England …

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Carbapenem-resistant Enterobacteriaceae dispersal from sinks is linked to drain position and drainage rates in a laboratory model system

Paz Aranega-Bou, Ryan George, N.Q. Verlander, Susan Paton et autres

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A Large, Refractory Nosocomial Outbreak of Klebsiella pneumoniae Carbapenemase-Producing Escherichia coli Demonstrates Carbapenemase Gene Outbreaks Involving Sink Sites Require Novel Approaches to Infection Control

Valérie Decraene, Hang T. T. Phan, Ryan George, David H. Wyllie et autres

Carbapenem-resistant Enterobacteriaceae (CRE) represent a health threat, but effective control interventions remain unclear. Hospital wastewater sites are increasingly being highlighted as important potential reservoirs.

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