Yao Bi

Cholangiocarcinoma:Unveiling the cold tumor microenvironment and strategies for immune rejuvenation

Wenqi Xu, Shuhan LIU, Longlong Sun, Yao Bi et autres

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Chronotype as a risk factor for adolescent depression and anxiety: The mediating roles of sleep and social functioning

Xiaofeng Zhao, Yao Bi, Sa Xiao, Wenli Zhu

BACKGROUND: Adolescents with an evening chronotype are at higher risk for mental health problems, such as depression and anxiety. However, the mechanisms underlying this relationship are not well understood. Sleep disturbances and impaired social functioning may mediate this association. AIM: To examine …

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The cGAS‒STING pathway in colorectal cancer: bridging innate immunity and therapeutic strategies

Wenjing Li, Guang‐Hui Dong, Yao Bi, Longlong Sun et autres

Colorectal cancer (CRC) continues to be a predominant cause of cancer-related mortality worldwide, with existing therapies constrained by systemic toxicity, resistance, and inadequate tumor targeting. While immunotherapy has potential in specific CRC subtypes, its overall effectiveness is still limited. The cyclic GMP‒AMP …

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2′,4′-dihydroxychalcone induces ferroptosis through ERO1A/GPX4 regulatory axis in cholangiocarcinoma

Tong Wang, Xuebing Zhou, Nanmiao Wang, Zhaoxia Su et autres

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Cordycepin: A Promising Anticancer Compound from Traditional Chinese Medicine

Yibang Li, Nanmiao Wang, Yao Bi, Wanshan Yang et autres

As cancer continues to pose a significant threat to human health, the search for effective therapeutic agents has become a critical focus in medical research. Cordyceps is a fungus used in traditional Chinese medicine (TCM) valued for its potential health benefits, which …

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PANoptosis: A new era for anti-cancer strategies

Yuan Li, Yao Bi, Wenjing Li, Junjie Piao et autres

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Research progress on ferroptosis in colorectal cancer

Yuan Li, Yao Bi, Wenjing Li, Yingshi Piao et autres

Ferroptosis is a new form of cell death that differs from traditional forms of death. It is ferroptosis-dependent lipid peroxidation death. Colorectal cancer(CRC) is the most common tumor in the gastrointestinal tract with a long occultation period and a poor five-year prognosis. …

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[investigation on the triggers and the effect of healthy education on recurrence of vestibular migraine].

Bo Xiao, Yao Bi, Tianheng Zheng

Sleep disorder, airtight space intolerance, excessive stress, lack of exercise, and dietary preference may be related factors to trigger VM attacks. Healthy education can significantly improve the awareness of VMs, and promote patients to change their lifestyle and eating habits. It can …

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Effect of Jinlida on changes in expression of skeletal muscle lipid transport enzymes in fat-induced insulin resistance ApoE-/- mice

Xin Kinson Jin, Huixin Zhang, Yanfen Zhang, Wenwen Cui et autres

OBJECTIVE: To study the effect of Jinlida on changes in expression of skeletal muscle lipid transport enzymes in fat-induced insulin resistance ApoE -/- mice. METHOD: Eight male C57BL/6J mice were selected in the normal group (NF), 40 male ApoE -/- mice were …

The Effect of Combination of GuiZhi FuLing Capsule and Mifepristone on Adenomyosis

Yao Bi

Objective: To analyze the effect of Gui Zhi Fu Ling Capsule combined with mifepristone in the treatment of adenomyosis and its influence over serum sex hormone levels. Methods: According to the order of admission, 180 patients with adenomyosis in our hospital from …

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Comparative Study of Neoadjuvant Chemotherapy(NACT) Combined with Radiotherapy and Simple Radiotherapy for Local Advanced Cervical Cancer

Yao Bi

Objective To study the clinical effects of NACT combined with radiotherapy and simple radiotherapy for local advanced cervical cancer. Methods Clinical data of 80 patients with local advanced cervical cancer were retrospectively analyzed. They were divided into 2 groups according to different …

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Expression of CXCR4 in osteosarcoma and its clinical implication

Yao Bi

Objective To investigate the expression of chemokine( C-X-C motif) receptor 4( CXCR4) in human osteosarcoma tissue and its clinical implication. Methods Total 86 cases of osteosarcoma tissues obtained by surgical resection and confirmed by pathological examination. The expression levels of CXCR4 in …

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