Tong Wang

Cholangiocarcinoma:Unveiling the cold tumor microenvironment and strategies for immune rejuvenation

Wenqi Xu, Shuhan LIU, Longlong Sun, Yao Bi et autres

cn (code pays fourni par la source)

A novel oral vaccine strategy utilizing a plasmid with CAG promoter-driven alphavirus RdRp for Co-expression of NA epitope and adjuvant in attenuated Salmonella boosts immune responses against H9N2 in mice

Mingyue Wang, Yupeng Gao, Yuxi Zhang, Gerui Zhang et autres

cn (code pays fourni par la source)

CAFs-derived exosomes inhibits ferroptosis via GALNT14-mediated O-GalNAcylation of SLC7A11 in colorectal cencer

Huayang Pan, Jialu Guan, Lingfeng Guo, Shuo Ning et autres

cn (code pays fourni par la source)

Causal Effects of Plasma Metabolites on Leukemia: A Mendelian Randomization Study

Chang Jen Huang, Mengjie Li, Ye Xu, Tong Wang et autres

Background: Leukemia comprises heterogeneous hematologic malignancies, and whether circulating metabolites contribute causally to subtype-specific risk remains uncertain. Objectives: The aim of this study was to assess the causal effects of plasma metabolites for acute myeloid leukemia (AML), chronic myeloid leukemia (CML), acute …

cn (code pays fourni par la source)

Multi-omics data integration for enhanced cancer subtyping via interactive multi-kernel learning

Cao Hong-yan, Tong Wang, Zhaoyang Xu, Xin Zhao et autres

Cancer is a highly heterogeneous disease characterized by complex molecular changes. Subtypes identified through multi-omics data hold significant promise for improving prognosis and facilitating personalized precision treatment. Recent multi-omics integration methods have mostly focused on capturing complementary information from different data types, …

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In vitro activity of contezolid and other comparators against clinical Staphylococcus and Enterococcus : a multicenter study in China

Renjing Lu, Xue Li, Wenhang Yang, Jiawei Chen et autres

OBJECTIVE: To evaluate the in vitro activity of contezolid against clinical Staphylococcus and Enterococcus isolates from across China, and compare its performance with linezolid and other key agents. METHODS: A total of 2510 non-duplicate Gram-positive cocci isolates were collected from 70 hospitals …

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2′,4′-dihydroxychalcone induces ferroptosis through ERO1A/GPX4 regulatory axis in cholangiocarcinoma

Tong Wang, Xuebing Zhou, Nanmiao Wang, Zhaoxia Su et autres

cn (code pays fourni par la source)

[Circadian and non-circadian regulation of the male reproductive system and reproductive damage: advances in the role and mechanisms of clock genes].

Mengchao He, Ying-Zhong Dai, Yimeng Wang, Qing Li et autres

Recently, male reproductive health has attracted extensive attention, with the adverse effects of circadian disruption on male fertility gradually gaining recognition. However, the mechanism by which circadian disruption leads to damage to male reproductive system remains unclear. In this review, we first …

cn (code pays fourni par la source)

[Galectin-3 in the Lung Cancer Microenvironment: Immunomodulation and Therapeutic Breakthroughs].

Jiong Deng, Tong Wang

Lung cancer remains one of the most prevalent and deadly malignancies worldwide, with persistently low five-year survival rates. This poor prognosis is primarily attributed to challenges such as difficulties in early diagnosis, high tumor heterogeneity, and strong therapeutic resistance. Although recent advances …

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DDIT4 knockdown suppresses venous malformation progression by inhibiting NF-κB signaling as a potential therapeutic target

He Bei Yang, Jian Lin, Liang Li, Tong Wang et autres

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Graft-Versus-Host Disease as a Risk Factor for Heart Failure After Allogeneic Hematopoietic Stem Cell Transplantation: A Retrospective Cohort Study

Tong Wang, Qian Zhu, Hongfei Zhao, Huan Liu

cn (code pays fourni par la source)

Case Report: A Complex Multidisciplinary Surgical Approach for a Pediatric Patient With Congenital Meningoencephalocele

Li Z, Xiaojun Tang, Jidi Fu, Dongchao Pan et autres

Congenital meningoencephalocele is a rare condition where brain tissue and meninges protrude through a skull defect, often requiring complex surgical management. The authors report the case of a 14-year-old female with a frontoethmoidal meningoencephalocele, presenting with a progressively enlarging nasal mass since …

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