Andrew Conn

A Novel Modulator of Resistance for Oxaliplatin-Based Therapy for Colorectal Cancer: The ESCRT Family Member VPS4A

Noha M. Abdelrazik, Anjana Patel, Andrew Conn, Chris W. Sutton et autres

Drug resistance is still one of the main challenges for the treatment of colorectal cancer (CRC). Whilst some resistance mechanisms are well known, from the static therapy success rate, clearly, still much is undiscovered. Intracellular transport mechanisms have attracted attention as having …

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A Novel Modulator of Resistance for Oxaliplatin-Based Therapy for Colorectal Cancer: The Escrt Family Member VPS4A

Noha M. Abdelrazik, Anjana Patel, Andrew Conn, Chris W. Sutton et autres

Drug resistance is still one of the main challenges for the treatment of colorectal cancer (CRC). Whilst some resistance mechanisms are well-known, from the static therapy success rate clearly still much is undiscovered. Intracellular transport mechanisms have come under attention as having …

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Retrospective analysis of real-world treatment patterns and clinical outcomes in patients with advanced non-small cell lung cancer starting first-line systemic therapy in the United Kingdom

Jason Francis Lester, Carles Escriu, Sarah N. Khan, Emma R. Hudson et autres

BACKGROUND: The treatment landscape for advanced non-small cell lung cancer (aNSCLC) has evolved rapidly since immuno-oncology (IO) therapies were introduced. This study used recent data to assess real-world treatment patterns and clinical outcomes in aNSCLC in the United Kingdom. METHODS: Electronic prescribing …

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Retrospective Analysis of Real-World Treatment Patterns and Clinical Outcomes in Patients With Advanced Non-Small Cell Lung Cancer Starting First-Line Systemic Therapy in the United Kingdom

Jason Francis Lester, Carles Escriu, Sarah N. Khan, Emma R. Hudson et autres

Abstract Background: The treatment landscape for advanced non-small cell lung cancer (aNSCLC) has evolved rapidly since immuno-oncology (IO) therapies were introduced. This study used recent data to assess real-world treatment patterns and clinical outcomes in aNSCLC in the United Kingdom. Methods: Electronic …

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1379P Real-world (RW) clinical outcomes of patients with metastatic non-small cell lung cancer (mNSCLC) in the United Kingdom

J. Lester, Carles Escriu, Sabbir Khan, Emmanuel W. Hudson et autres

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Treatment patterns in patients with advanced non-small cell lung cancer (aNSCLC): real-world data from the United Kingdom

J. Lester, Sarah N. Khan, Charles S. Powell, Carles Escriu et autres

A case of fatal cetuximab-induced interstitial lung disease during the first weeks of treatment

Alaaeldin Shablak, Andrew Conn

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6013 POSTER DISCUSSION Cumulative Exposure to Bevacizumab (BV) After Progression Correlates With Increased Survival in Patients (pts) With Metastatic Colorectal Cancer (mCRC): a Time-dependent Analysis of the ARIES Observational Cohort Study

A. Grothev, Tanios Bekaii‐Saab, Herbert I. Hurwitz, M. Kozloff et autres

Erlotinib and docetaxel in relapsed non-small cell lung cancer: a single centre experience

Jane Hook, Caitriona MacDermott, Sue Cheeseman, Andrew Conn

Chemotherapy and radiotherapy in the treatment of colorectal cancer

Vanessa Alice Potter, Andrew Conn

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Identification of an HLA‐A*0201 cytotoxic T lymphocyte epitope specific to the endothelial antigen Tie‐2

Judith M. Ramage, Rachael L. Metheringham, Andrew Conn, Ian Spendlove et autres

Tie-2 stabilises pericyte-endothelial interactions during angiogenesis and is highly expressed on endothelium during several diseases, including arthritis, age-related macular degeneration and cancer. A vaccine that targets endothelium overexpressing Tie-2 may result in vessel damage and stimulate an inflammatory cascade resulting in disease …

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Preclinical Development of a DNA Vaccine for Colorectal Cancer

Andrew Conn, Ian Spendlove, Lindy G. Durrant, James Carmichael

Conference Abstract| July 01 2002 Preclinical Development of a DNA Vaccine for Colorectal Cancer Andrew Conn; Andrew Conn 1CRC Academic Unit of Clinical Oncology, University of Nottingham, Nottingham, UK Search for other works by this author on: This Site PubMed Google Scholar …

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