Patrick T. Wang

P3.12.74 IMM2510, an Anti-PD-L1/VEGF Bispecific Antibody Fusion Protein for Advanced IO-treated SQ-NSCLC: A Phase I Study

Patrick T. Wang, Yi Zhang, Aihua Wu, Shuai Gao et autres

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1352: IMMEDIATE RETURN OF ISLET FUNCTION AND INSULIN INDEPENDENCE AFTER SIMULTANEOUS INTRA AND EXTRAHEPATIC TRANSPLANTATION OF UNPURIFIED AUTOLOGOUS ISLETS IN TOTAL PANCREATECTOMY AND ISLET CELL TRANSPLANTATION

Patrick T. Wang, Onur Cagri Kutlu, Xiumin Xu, Jodie A. Barkin et autres

Smartphone accelerometers as tools to study the effect of socioeconomic disparities in neurosurgical outcomes: a multi-institutional retrospective analysis

Daksh Chauhan, Hasan S. Ahmad, Kristen H. Park, Yohannes G. Ghenbot et autres

OBJECTIVE: Smartphones and wearable devices can be effective tools to objectively assess patient mobility and well-being before and after spine surgery. In this retrospective observational study, the authors investigated the relationship between these longitudinal perioperative patient activity data and socioeconomic and demographic …

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Glycogen synthase GYS1 overactivation contributes to glycogen insolubility and malto-oligoglucan-associated neurodegenerative disease

Silvia Nitschke, Alina P. Montalbano, Megan E Whiting, Brandon H. Smith et autres

Polyglucosans are glycogen molecules with overlong chains, which are hyperphosphorylated in the neurodegenerative Lafora disease (LD). Brain polyglucosan bodies (PBs) cause fatal neurodegenerative diseases including Lafora disease and adult polyglucosan body disease (ABPD), for which treatments, biomarkers, and good understanding of their …

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Machine Learning Models Leveraging Smartphone-Based Patient Mobility Data Can Accurately Predict Functional Outcomes After Spine Surgery

Hasan S. Ahmad, Daksh Chauhan, Mert Marcel Dagli, Ryan Turlip et autres

Objective: The development of adjacent segment disease or the progression of spondylosis following the surgical treatment of spinal stenosis and spondylolisthesis is well documented and can lead to subsequent functional decline after a successful index surgery. The early detection of negative inflection …

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HE association between vitamin D and low skeletal muscle mass in young adult population: A cross-sectional study of NHANES data from 2011 to 2018

Yangyang Li, Tianchang Xie, Patrick T. Wang

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Investigating Incidence of Nausea and Vomiting in Patients Receiving Concurrent Chemoradiotherapy: A Real-World Cohort Study

Lili Wang, Jian Zang, Yong Zhang, Yu Yin et autres

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Laforin targets malin to glycogen in Lafora progressive myoclonus epilepsy

Sharmistha Mitra, Baozhi Chen, Patrick T. Wang, Erin E. Chown et autres

Glycogen is the largest cytosolic macromolecule and is kept in solution through a regular system of short branches allowing hydration. This structure was thought to solely require balanced glycogen synthase and branching enzyme activities. Deposition of overlong branched glycogen in the fatal …

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Association of BST1 polymorphism with idiopathic restless legs syndrome in Chinese population

Yi-Bin Huang, Patrick T. Wang, Qi Luo, Jun Ma

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Non-invasive remote ischemic postconditioning stimulates neurogenesis during the recovery phase after cerebral ischemia

Patrick T. Wang

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Items comparison of questionnaires, scales and clinical outcomes used in ankylosing spondylitis based on the International Classification of Functioning, Disability and Health: A systematic review

Patrick T. Wang

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The adverse effects of perinatal exposure to nonylphenol on carbohydrate metabolism in male offspring rats

Jin Yang, Jie Yu, Patrick T. Wang, Yuhan Luo et autres

Background: We sought to investigate the adverse effects of perinatal exposure to nonylphenol (NP) on carbohydrate metabolism of male offspring rats. Methods: Thirty-two healthy pregnant Sprague Dawley rats were randomly divided into four groups, control normal diet group (C), NP normal diet …

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