You-Joung Kim

Author Correction: SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function

Mihyun Bae, Junyeop Daniel Roh, You-Joung Kim, Seong Soon Kim et autres

[Image: see text]

kr, hk (code pays fourni par la source)

mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi et autres

Retinal progenitor cells (RPCs) divide in limited numbers to generate the cells comprising vertebrate retina. The molecular mechanism that leads RPC to the division limit, however, remains elusive. Here, we find that the hyperactivation of mechanistic target of rapamycin complex 1 (mTORC1) …

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Author response: mTORC1-induced retinal progenitor cell overproliferation leads to accelerated mitotic aging and degeneration of descendent Müller glia

Soyeon Lim, You-Joung Kim, Sooyeon Park, Ji-heon Choi et autres

Comprehensive mouse genetic analyses show, by having mTORC1 constitutively active, a RPC divides and exhausts mitotic capacity faster than neighboring RPCs, and thus produces retinal cells that degenerate with aging-related changes in the mature mouse retina.

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Retinoid Metabolism in the Degeneration of Pten-Deficient Mouse Retinal Pigment Epithelium

You-Joung Kim, Sooyeon Park, Taejeong Ha, Seungbeom Kim et autres

In vertebrate eyes, the retinal pigment epithelium (RPE) provides structural and functional homeostasis to the retina.The RPE takes up retinol (ROL) to be dehydrogenated and isomerized to 11-cis-retinaldehyde (11-cis-RAL), which is a functional photopigment in mammalian photoreceptors.As excessive ROL is toxic, the …

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Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity

Le Dai, Soyeon Lim, Kwang Wook Min, Jun Woo Park et autres

The retinal pigment epithelium (RPE) forms a monolayer sheet separating the retina and choroid in vertebrate eyes. The polarized nature of RPE is maintained by distributing membrane proteins differentially along apico-basal axis. We found the distributions of these proteins differ in embryonic, …

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SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function

Mihyun Bae, Junyeop Daniel Roh, You-Joung Kim, Seong Soon Kim et autres

Glycine transporters (GlyT1 and GlyT2) that regulate levels of brain glycine, an inhibitory neurotransmitter with co-agonist activity for NMDA receptors (NMDARs), have been considered to be important targets for the treatment of brain disorders with suppressed NMDAR function such as schizophrenia. However, …

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Zinc increases the phagocytic capacity of canine peripheral blood phagocytes in vitro

You-Joung Kim, Ji‐Houn Kang, Mhan‐Pyo Yang

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Clinical Features and Prognostic Factors in Ischemic Colitis.

Sung‐hoon Jung, Kang‐Moon Lee, Jeong‐Seon Ji, Woo-Chul Chung et autres

Background/Aims: Ischemic colitis mainly occurs in elderly patients and encompasses a wide clinical spectrum from mild, transient to severe and gangrenous forms. Since life expectancy is now increasing, more often physicians will encounter patients with this disease entity. Our aim was to …

Phase equilbria and formation kinetics of clathrate solutions with cyclic ethers = 사이클릭 에테르계를 포함하는 크러스레이트 용액의 상평형 및 생성 속도론

You-Joung Kim, 김유정