Valentina Frisina

CD4/CD8 ratio in pregnant women with HIV and its association with pregnancy outcome: data from a national study in Italy

Marco Floridia, Carmela Pinnetti, Giulia Masuelli, Arsenio Spinillo et autres

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Weight Gain during Pregnancy in Women with HIV Receiving Different Antiretroviral Regimens

Marco Floridia, Giulia Masuelli, Beatrice Tassis, Laura Franceschetti et autres

Background No published studies have evaluated in pregnant women with HIV weight gain with different antiretroviral drug classes. Methods Data from a national cohort study were used. We compared absolute weight gain and occurrence of excessive weight gain in women with HIV …

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Vaginal delivery in women with HIV in Italy: results of 5 years of implementation of the national SIGO-HIV protocol

Cecilia Tibaldi, Giulia Masuelli, Matilde Sansone, Beatrice Tassis et autres

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Atazanavir and darunavir in pregnant women with HIV: evaluation of laboratory and clinical outcomes from an observational national study

Marco Floridia, Giulia Masuelli, Marina Ravizza, Beatrice Tassis et autres

Background: Atazanavir and darunavir represent the main HIV PIs recommended in pregnancy, but comparative data in pregnant women are limited. We assessed the safety and activity profile of these two drugs in pregnancy using data from a national observational study. Methods: Women …

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Pregnant with HIV before age 25: data from a large national study in Italy, 2001–2016

Marco Floridia, Giulia Masuelli, Enrica Tamburrini, Irene Cetin et autres

Young pregnant women with HIV may be at significant risk of unplanned pregnancy, lower treatment coverage, and other adverse pregnancy outcomes. In a large cohort of pregnant women with HIV in Italy, among 2979 pregnancies followed in 2001-2016, 9·0% were in women …

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Evolving treatment implementation among HIV–infected pregnant women and their partners: results from a national surveillance study in Italy, 2001–2015

Marco Floridia, Valentina Frisina, Marina Ravizza, Anna Maria Marconi et autres

BACKGROUND: The current global and national indications for antiretroviral treatment (ART, usually triple combination therapy) in adolescent and adults, including pregnant women, recommend early ART before immunologic decline, pre-exposure chemoprophylaxis (PrEP), and treatment of HIV-negative partners in serodiscordant couples. There is limited …

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Rate, correlates and outcomes of repeat pregnancy in HIV ‐infected women

Marco Floridia, Enrica Tamburrini, Giulia Masuelli, Pasquale Martinelli et autres

OBJECTIVES: The aim of the study was to assess the rate, determinants, and outcomes of repeat pregnancies in women with HIV infection. METHODS: Data from a national study of pregnant women with HIV infection were used. Main outcomes were preterm delivery, low …

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Acceptance of and adherence to hygiene measures to prevent primary cytomegalovirus infection in pregnancy

Maria Grazia Revello, Giulia Masuelli, Valentina Frisina, Tullia Todros

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Pregnancy outcomes and cytomegalovirus DNAaemia in HIV-infected pregnant women with CMV

Marco Floridia, Maria Franca Pirillo, Anna Degli Antoni, Atim Molinari et autres

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Evaluation of quantitative fFn test in predicting the risk of preterm birth

Michela Centra, Giuliana Coata, Elena Picchiassi, Luisa Alfonsi et autres

OBJECTIVE: To evaluate diagnostic accuracy of quantitative fetal fibronectin (qfFN) test in predicting preterm birth (PTB) risk <34 weeks' gestation or within 14 days from testing. We explored the predictive potential of the test in five-predefined PTB risk categories based on predefined …

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An effective and feasible approach to prevention of primary cytomegalovirus infection in pregnancy

Maria Grazia Revello, Valentina Frisina, Giovanna Oggè, Alessia Arossa et autres

In the absence of a cytomegalovirus (CMV) vaccine, other strategies for prevention of primary infection in pregnancy should be considered. Behavioural interventions have been reported to significantly decrease seroconversion rate among seronegative pregnant women. We report here on a recently completed controlled …

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Prevention of Primary Cytomegalovirus Infection in Pregnancy

Maria Grazia Revello, Cecilia Tibaldi, Giulia Masuelli, Valentina Frisina et autres

BACKGROUND: Cytomegalovirus (CMV) is the leading infectious agent causing congenital sensorineural hearing loss and psychomotor retardation. CMV vaccine is currently unavailable and treatment options in pregnancy are limited. Susceptible pregnant women caring for children are at high risk for primary infection. CMV …

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