Fanlei Kong

Therapeutic Effects of Intratracheally Nebulized Carnosine-Loaded Liposomes on Lipopolysaccharide-Induced Acute Lung Injury

Chao Fang, Lixin Xie, Daihan Xie, Jingting Yin et autres

Introduction: Acute lung injury (ALI) is characterized by severe inflammation and oxidative stress. However, effective pharmacological interventions for ALI remain limited. Carnosine, an endogenous dipeptide known for its redox-regulating and immunomodulatory activities, has demonstrated promising protective effects. In the present study, inhalable …

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Association between social capital, eHealth literacy, and digital health literacy among undergraduate students in China: a multigroup analysis based on gender differences

Yangyang Fu, Deyong Lv, Rui Chen, Kaiyuan Feng et autres

Purpose The primary objective of this study was to explore gender differences in the relationships among social capital, eHealth literacy (EHL), and digital health literacy (DHL) among undergraduate students in China, and to support the implementation of the Healthy China and Digital …

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Feasibility of artificial intelligence-based rapid on-site evaluation for the diagnosis of pulmonary disease

Y Y Chen, Chengcheng Du, Pengchen Gu, C Li et autres

Introduction: This study aimed to investigate the clinical feasibility of artificial intelligence-rapid on-site evaluation (AI-ROSE) based on exfoliated cell blotting from percutaneous puncture biopsy specimens for diagnosing pulmonary lesions and to provide a reference for intraoperative rapid diagnosis. Methods: A total of …

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Pillbox and patient-oriented manual interventions to improve medication knowledge, attitudes, and practices among older adults with multimorbidity in Shanghai, China

Changjia Fan, Qi Tang, Lisha Li, Huanyun Wu et autres

BACKGROUND: Multimorbidity and polypharmacy are major challenges for older adults with multimorbidity (OAM) in China, yet demand-side interventions remain limited. This study aimed to assess the effectiveness of pillbox (PB) and patient-oriented manual (POM) interventions in improving medication knowledge (MK), attitudes (MA), …

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Safety and efficacy of CT-guided percutaneous microwave ablation for stage I non-small cell lung cancer combined with moderate-to-severe pulmonary dysfunction

Yuxian Chen, Chengcheng Du, Chunhai Li, Hong Meng et autres

Introduction To evaluate the safety and efficacy of microwave ablation (MWA) for stage I non-small cell lung cancer (NSCLC) in patients with pulmonary dysfunction. Methods A retrospective study was conducted involving 1,635 patients who underwent MWA between January 2018 and December 2024. …

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Lipid-Engineered Small-Sized Metal-Organic Frameworks for Targeted Delivery of Anlotinib in Lung Cancer Treatment

Chao Fang, Daihan Xie, Fanlei Kong, Xin Yu et autres

Purpose: In this study, we report the design and evaluation of Anlo@MOF-Lipo (AML), a liposome coated, small sized MIL-101(Fe) metal-organic framework (MOF) for targeted delivery of the multi target tyrosine kinase inhibitor anlotinib in lung cancer treatment. Methods: In detail, the biomimetic …

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Relationship between maternal social support and undernutrition among children under 5 years in Siem Reap Province, Cambodia: the chain mediating roles of household food insecurity and maternal depression

Mengleang Rek, Nabila Ibn Ziyat, Rui Chen, Xixing Xu et autres

BACKGROUND: Undernutrition among children under five years (CUFY) is a leading global public health issue worldwide, including in Cambodia. This study aimed to determine the prevalence of undernutrition and the mediating effect of maternal depression and household food insecurity on the association …

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Additional file 1 of Relationship between maternal social support and undernutrition among children under 5 years in Siem Reap Province, Cambodia: the chain mediating roles of household food insecurity and maternal depression

Mengleang Rek, Nabila Ibn Ziyat, Rui Chen, Xixing Xu et autres

Supplementary Material 1.

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Additional file 1 of Relationship between maternal social support and undernutrition among children under 5 years in Siem Reap Province, Cambodia: the chain mediating roles of household food insecurity and maternal depression

Mengleang Rek, Nabila Ibn Ziyat, Rui Chen, Xixing Xu et autres

Supplementary Material 1.

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Preclinical evaluation of a fluorine-18 labeled transthyretin small interfering RNA transfection platform as an imaging probe for liver fibrosis

Dai Li, Fanlei Kong, Qiyong Guo

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Study of the microenvironment of the lung flora in female lung adenocarcinoma patients: from benign lesions to invasive lung adenocarcinomas

Chengcheng Du, Daqian Sun, Yuxian Chen, Jinhu Li et autres

BACKGROUND: The number of female lung adenocarcinoma patients is increasing annually, but these patients are difficult to diagnose in the early stage without obvious clinical symptoms, leading to late-stage diagnoses and poor outcomes. Recent studies have shown that the lung microbiota is …

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Study of the Microenvironment of the Lung Flora in Female Lung Adenocarcinoma Patients: From Benign Lesions to Invasive Lung Adenocarcinoma

Chengcheng Du, Daqian Sun, Yuxian Chen, Jinhu Li et autres

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