Accès ouvert
2026
article
OpenAlex
Michael Busche, Anne M. Runkel, Min Xu, Katherine A. Klimpel et autres
Plant cells are connected by plasmodesmata (PD), membrane-lined channels that facilitate cell-to-cell transport. Forward genetic screens to uncover regulators of PD transport identified mutants with increased ( ise1 to ise4 ) or decreased ( dse1 ) PD trafficking during embryogenesis. Despite their …
us, cn
(code pays fourni par la source)
Accès ouvert
2023
article
OpenAlex
Jennifer M. Frost, Jaehoon Lee, Ping-Hung Hsieh, Samuel J. H. Lin et autres
BACKGROUND: H2A.X is an H2A variant histone in eukaryotes, unique for its ability to respond to DNA damage, initiating the DNA repair pathway. H2A.X replacement within the histone octamer is mediated by the FAcilitates Chromatin Transactions (FACT) complex, a key chromatin remodeler. …
gb, us, kr, pr
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Jennifer M. Frost, Jaehoon Lee, Ping-Hung Hsieh, Samuel J. H. Lin et autres
Abstract Background H2A.X is an H2A variant histone in eukaryotes, unique for its ability to respond to DNA damage, initiating the DNA repair pathway. H2A.X replacement within the histone octamer is mediated by the FAcilitates Chromatin Transactions (FACT) complex, a key chromatin …
us, kr
(code pays fourni par la source)
2023
article
OpenAlex
Anne M. Runkel, Aline Sparwasser, Annette Hasenburg
de, at
(code pays fourni par la source)
Accès ouvert
2023
preprint
OpenAlex
Jennifer M. Frost, Jaehoon Lee, Ping-Hung Hsieh, Samuel J. H. Lin et autres
Abstract H2A.X is an H2A variant histone in eukaryotes, unique for its ability to respond to DNA damage, initiating the DNA repair pathway. H2A.X replacement within the histone octamer is mediated by the FAcilitates Chromatin Transactions (FACT) complex, a key chromatin remodeler. …
gb, us, kr
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Anne-Sophie Heimes, Katrin Almstedt, Slavomir Krajnak, Anne M. Runkel et autres
Background: Monoclonal antibodies against PD-1 or PD-L1 have been established in clinical practice for the treatment of both early and advanced/metastatic triple-negative breast cancer. Beyond the established immune checkpoints (ICPs) (PD-1 and CTLA-4), additional ICPs, such as lymphocyte activation gene-3 (LAG-3), are …
de
(code pays fourni par la source)
Accès ouvert
2022
preprint
OpenAlex
Anne-Sophie Heimes, Katrin Almstedt, Slavomir Krajnak, Anne M. Runkel et autres
Background: Monoclonal antibodies against PD-1 or PD-L1 are established in clinical practice for the treatment of both early and advanced/metastatic triple-negative breast cancer. Beyond the established immune checkpoints (ICPs) (PD-1 and CTLA-4) additional ICPs such as lymphocyte activation gene-3 (LAG-3) are subject …
de
(code pays fourni par la source)
Accès ouvert
2022
article
OpenAlex
Helmut Kleinwechter, Katharina S. Weber, Nina Mingers, Babett Ramsauer et autres
de, us, in, at
(code pays fourni par la source)
2019
article
OpenAlex
Parnian Parvanta, Anne M. Runkel
Eine Infektion mit Streptokokken der Gruppe B ist weiterhin die Hauptursache für schwere neonatale Infektionen. In Deutschland manifestieren sich 60% der Fälle einer invasiven GBS-Infektion als Early Onset Sepsis (EOS). Zeitgleich führt eine Übertherapie zu Resistenzen sowie zu negativen Auswirkungen auf das …
Accès ouvert
2016
article
OpenAlex
Jacob O. Brunkard, Anne M. Runkel, Patricia Zambryski
Stromules, or "stroma-filled tubules", are narrow, tubular extensions from the surface of the chloroplast that are universally observed in plant cells but whose functions remain mysterious. Alongside growing attention on the role of chloroplasts in coordinating plant responses to stress, interest in …
us
(code pays fourni par la source)
2016
article
OpenAlex
Jacob O. Brunkard, Anne M. Runkel, Patricia Zambryski
Stromules, or "stroma-filled tubules", are narrow, tubular extensions from the surface of the chloroplast that are universally observed in plant cells but whose functions remain mysterious. Alongside growing attention on the role of chloroplasts in coordinating plant responses to stress, interest in …
us
(code pays fourni par la source)
Accès ouvert
2016
article
OpenAlex
Rezzak Yılmaz, Stefanie Behnke, Inga Liepelt‐Scarfone, Benjamin Röeben et autres
BACKGROUND AND PURPOSE: Deficits in cognition have been reported in Parkinson's disease (PD) already in the early and even in the pre-motor stages. Whilst substantia nigra hyperechogenicity measured by transcranial B-mode sonography (TCS) represents a strong PD marker and is associated with …
de
(code pays fourni par la source)