Edoardo Scomazzon

Salvage treatment patterns in multiple myeloma patients progressing after lenalidomide maintenance: A real‐life study from European Myeloma Network ( EMN ) Italy

Gregorio Barilà, Angela Grassi, Valeria Ruocco, Carmine Liberatore et autres

The extensive use of lenalidomide (Len) in the first-line treatment of multiple myeloma (MM) has resulted in an increased frequency of patients who have been exposed or are refractory to Len (Len-R) at first relapse. However, the outcome of Len-R patients treated …

it, my (code pays fourni par la source)

Hip resection arthroplasty as a primary treatment of displaced neck fracture in non-ambulatory and fragile patients

Dario Regis, Elisa Sartore, Edoardo Scomazzon, R. Borgese et autres

Due to the increasing ageing population, femoral neck fracture (FNF) is a common and significant public health issue in the elderly, as it significantly impacts patients' quality of life, frequently leading to severe disability. Undoubtedly, hip replacement is the standard current of …

it (code pays fourni par la source)

The treatment of patients primary refractory or with sub-optimal response to d-VTD induction: An italian real-life Study

Gregorio Barilà, Francesco Tarantini, Alfonso Piciocchi, Maria Livia Del Giudice et autres

Abstract Despite the improvement in the treatment of multiple myeloma (MM) patients, there is still a consistent fraction of patients who have a primary refractory MM (PRMM) or relapse early during treatment. Up to now in Italy the treatment for newly diagnosed …

it (code pays fourni par la source)

Lenalidomide maintenance after bortezomib, thalidomide and dexamethasone (VTD) induction and autologous stem cell transplantation: an Italian real-life study of 602 patients

Gregorio Barilà, Angela Grassi, Concetta Conticello, Roberto Mina et autres

Not available.

it (code pays fourni par la source)

Lenalidomide Maintenance after VTD Induction and Autologous Stem Cell Transplantation: An Italian Real-Life Study of 558 Patients

Gregorio Barilà, Angela Grassi, Concetta Conticello, Roberto Mina et autres

According to 2021 ESMO guidelines, treatment of newly diagnosed (ND) transplant eligible (TE) Multiple Myeloma (MM) patients is settled by an induction phase followed by single or tandem autologous stem cell transplantation (ASCT) and Lenalidomide (Len) maintenance. Len maintenance was approved in …

it (code pays fourni par la source)

P-129 Real world evidence of prognostic impact of t(14;16) translocation in multiple myeloma: a report of the myeloma triveneto working group

Gregorio Barilà, Laura Bonaldi, Laura Pavan, Annalisa Martines et autres

us, it, es (code pays fourni par la source)

P20 LENALIDOMIDE MAINTENANCE AFTER VTD INDUCTION AND AUTOLOGOUS STEM CELL TRANSPLANTATION: PRELIMINARY RESULTS OF A REAL-LIFE STUDY INCLUDING 389 PATIENTS

G. Barilà, Anna Pascarella, Concetta Conticello, Roberto Mina et autres

According to 2021 ESMO guidelines, treatment of newly diagnosed (ND) transplant eligible (TE) Multiple Myeloma (MM) patients is settled by an induction phase followed by single or tandem autologous stem cell transplantation (ASCT) and Lenalidomide (Len) maintenance. Before the recent approval of …

it (code pays fourni par la source)

The combination of complex karyotype subtypes and IGHV mutational status identifies new prognostic and predictive groups in chronic lymphocytic leukaemia

Andrea Visentin, Laura Bonaldi, Gian Matteo Rigolin, Francesca Romana Mauro et autres

BACKGROUND: Complex karyotype (CK) is a heterogeneous category with a negative impact in chronic lymphocytic leukaemia (CLL). Our group has recently reported that CK patients with major structural abnormalities (i.e. CK2) are characterised by a worse prognosis, as compared to other lesions …

it (code pays fourni par la source)

HSP70/HSF1 axis, regulated via a PI3K/AKT pathway, is a druggable target in chronic lymphocytic leukemia

Federica Frezzato, Flavia Raggi, Veronica Martini, Filippo Severin et autres

Considering the role played by the heat shock protein of 70 kDa (HSP70) in cancer, we characterized this protein and its major regulator, the heat shock factor 1 (HSF1), in chronic lymphocytic leukemia (CLL). We found both HSP70 and HSF1 overexpressed in …

it (code pays fourni par la source)

Prognostic and Predictive Effect of IGHV Mutational Status and Load in Chronic Lymphocytic Leukemia: Focus on FCR and BR Treatments

Andrea Visentin, Monica Facco, Carmela Gurrieri, Elisa Pagnin et autres

it (code pays fourni par la source)

The Combination of Complex Karyotypes' Subtypes and IGHV Mutational Status Provides Prognostic and Predictive Information in Chronic Lymphocytic Leukemia

Andrea Visentin, Laura Bonaldi, Gian Matteo Rigolin, Francesca Romana Mauro et autres

Abstract INTRODUCTION. Complex karyotype (CK), defined by the presence of at least 3 chromosomal abnormalities, is a heterogeneous cytogenetic category associated with adverse prognosis in several hematologic malignancies. Recently, Rigolin et al. provided evidence that CK with major structural abnormalities (CK2) at …

it (code pays fourni par la source)

A Scoring System to Predict the Risk of Atrial Fibrillation in Chronic Lymphocytic Leukemia and Its Validation in a Cohort of Ibrutinib-Treated Patients

Andrea Visentin, Marina Deodato, Francesca Romana Mauro, Francesco Autore et autres

Abstract BACKGROUD. The B-cell receptor inhibitor ibrutinib has significantly improved treatment and overall management of chronic lymphocytic leukemia (CLL). Although several data derived from clinical trials suggest that ibrutinib increases the risk of atrial fibrillation (AF), the incidence of AF in a …

it (code pays fourni par la source)